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John G. Topliss

Observed names: J. G. TOPLISS, J. G. Topliss, J. Topliss, J.G. TOPLISS, J.G. Topliss, JOHN G. TOPLISS, John Topliss, Topliss, John G.
Observed institutions: Universidad de Panamá, Merck & Co., Inc., Rahway, NJ, USA (United States), University of Kansas, The University of Queensland, University of Michigan, Royal Perth Hospital, Addis Ababa University, KTH Royal Institute of Technology, Universidad de Navarra
ORCID: 0000-0002-8916-9405
Observed ORCID: 0000-0002-8916-9405
OpenAlex ID: A5032896348
Chance factors in studies of quantitative structure-activity relationships
1979 · John G. Topliss, Robert P. Edwards · Journal of Medicinal Chemistry · 676
Utilization of operational schemes for analog synthesis in drug design
1972 · John G. Topliss · Journal of Medicinal Chemistry · 467
Chance correlations in structure-activity studies using multiple regression analysis
1972 · John G. Topliss, Robert J. Costello · Journal of Medicinal Chemistry · 414
QSAR Model for Drug Human Oral Bioavailability
2000 · Fumitaka Yoshida, John G. Topliss · Journal of Medicinal Chemistry · 304
A manual method for applying the Hansch approach to drug design
1977 · John G. Topliss · Journal of Medicinal Chemistry · 224
New Class of Antihypertensive Agents
1961 · A. A. Rubin, F. E. Roth, et al. · Science · 124
Natural and synthetic substances related to human health (IUPAC Technical Report)
2002 · J. G. Topliss, A. M. Clark, et al. · Pure and Applied Chemistry · 65
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Unified Model for the Corneal Permeability of Related and Diverse Compounds with Respect to Their Physicochemical Properties
1996 · Fumitaka Yoshida, John G. Topliss · Journal of Pharmaceutical Sciences · 56
Correlation of antihypertensive activity with structure in a series of 2H-1,2,4-benzothiadiazine 1,1-dioxides using the substituent constant approach
1972 · John G. Topliss, Milton D. Yudis · Journal of Medicinal Chemistry · 52
1-Poly(fluoroalkyl)benzodiazepines
1973 · Martin Steinman, John G. Topliss, et al. · Journal of Medicinal Chemistry · 51
Antihypertensive Agents. III.1 3-Hydroxy-3-phenylphthalimidines
1964 · John G. Topliss, Leroy M. Konzelman, et al. · Journal of Medicinal Chemistry · 31
Some observations on classical QSAR
1993 · John G. Topliss · Perspectives in Drug Discovery and Design · 30
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117. A total synthesis of (±)-ferruginol
1957 · F. E. King, T. J. King, et al. · Journal of the Chemical Society (Resumed) · 29
Antihypertensive Agents. I. Non-diuretic 2H-1,2,4-Benzothiadiazine 1,1-Dioxides
1963 · John G. Topliss, Margaret H. Sherlock, et al. · Journal of Medicinal Chemistry · 24
Natural and Synthetic Substances Related to Human Health
2016 · J. G. Topliss, A. M. Clark, et al. · IUPAC Standards Online · 21
The Chemistry of the Natural Order Cupressales. XVI. Heartwood Constituents of Chamaecyparis nootkatensis (Lamb.) Spach. The Structure of Chamic and Chaminic Acids.
1956 · H. Erdtman, W. E. Harvey, et al. · Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · 21
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Cyclic derivatives of 3,3-diphenylalanine (Dip) (II), novel α-amino acids for peptides of biological interest
1993 · V.G. Beylin, Huai G. Chen, et al. · Tetrahedron Letters · 19
3-Substituted Dihydrobenzothiadiazine 1,1-Dioxides as Diuretic Agents1
1961 · JOHN G. TOPLISS, MARGARET H. SHERLOCK, et al. · The Journal of Organic Chemistry · 19
.pi.-Substituent constants for the 2H-1,2,4-benzothiadiazine 1,1-dioxide system
1972 · John G. Topliss, Milton D. Yudis · Journal of Medicinal Chemistry · 18
Antihypertensive Agents. II.1 3-Substituted 2H-1,2,4-Benzothiadiazine 1,1-Dioxides
1964 · John G. Topliss, Leroy M. Konzelman, et al. · Journal of Medicinal Chemistry · 17
The Chemistry of the Natural-Order Cupressales. XVIII. Nootkatene, a New Sesquiterpene Type Hydrocarbon from the Heartwood of Chamaecyparis nootkatensis (Lamb.) Spach.
1957 · H. Erdtman, J. G. Topliss, et al. · Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · 13
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Education of medicinal chemists in departments of medicinal chemistry (U.S.A.)
1998 · C. Robin Ganellin, Lester A. Mitscher, et al. · Medicinal Research Reviews · 12
Quantitative structure-activity relations in the .DELTA.6-6-substituted progesterone series. Reappraisal
1975 · John G. Topliss, Elliot L. Shapiro · Journal of Medicinal Chemistry · 12
QSAR Model for Drug Human Oral Bioavailability.
2000 · Fumitaka Yoshida, John G. Topliss · Journal of Medicinal Chemistry · 11
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The measurement of molecular diversity by receptor site interaction simulation
1998 · Camden A. Parks, Gordon M. Crippen, et al. · Journal of Computer-Aided Molecular Design · 11
Works count: 74
Citation count: 2,881
H-index: 18
I10-index: 30
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