Author

Emanuela Nizi

Observed name: E. Nizi

Institution: IRBM

Observed institutions: University of Siena, University of Messina, Merck & Co., Inc., Rahway, NJ, USA (United States), University of Würzburg, Christian-Albrechts-Universität zu Kiel, IRBM

ORCID: 0000-0003-3715-2174

Observed ORCID: 0000-0003-3715-2174

OpenAlex ID: A5033705171

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

2008 · Vincenzo Summa, Alessia Petrocchi, et al. · Journal of Medicinal Chemistry · 652

Development of Peptidomimetics with a Vinyl Sulfone Warhead as Irreversible Falcipain-2 Inhibitors

2008 · Roberta Ettari, Emanuela Nizi, et al. · Journal of Medicinal Chemistry · 223

Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor

2012 · Steven Harper, John A. McCauley, et al. · ACS Medicinal Chemistry Letters · 208

Dihydroxypyrimidine-4-carboxamides as Novel Potent and Selective HIV Integrase Inhibitors

2007 · Paola Pace, M. Emilia Di Francesco, et al. · Journal of Medicinal Chemistry · 80

Novel Peptidomimetics Containing a Vinyl Ester Moiety as Highly Potent and Selective Falcipain-2 Inhibitors

2009 · Roberta Ettari, Nicola Micale, et al. · Journal of Medicinal Chemistry · 75

Discovery and Synthesis of HIV Integrase Inhibitors: Development of Potent and Orally Bioavailable N-Methyl Pyrimidones

2007 · Cristina Gardelli, Emanuela Nizi, et al. · Journal of Medicinal Chemistry · 67

The monoethyl ester of meconic acid is an active site inhibitor of HCV NS5B RNA-dependent RNA polymerase

2004 · Paola Pace, Emanuela Nizi, et al. · Bioorganic & Medicinal Chemistry Letters · 56

Design and Synthesis of Bicyclic Pyrimidinones as Potent and Orally Bioavailable HIV-1 Integrase Inhibitors

2008 · Ester Muraglia, Olaf Kinzel, et al. · Journal of Medicinal Chemistry · 53

Nonpeptidic Vinyl and Allyl Phosphonates as Falcipain‐2 Inhibitors

2008 · Roberta Ettari, Emanuela Nizi, et al. · ChemMedChem · 47

Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs

2016 · Jesus M. Ontoria, Giacomo Paonessa, et al. · ACS Medicinal Chemistry Letters · 42

Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production

2017 · Alessandra Guidi, Cristiana Lalli, et al. · PLoS neglected tropical diseases · 35

Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides

2018 · Alberto Bresciani, Jesus M. Ontoria, et al. · ACS Medicinal Chemistry Letters · 32

Peptidomimetic nitrile inhibitors of malarial protease falcipain-2 with high selectivity against human cathepsins

2018 · Emanuela Nizi, Alessio Sferrazza, et al. · Bioorganic & Medicinal Chemistry Letters · 27

Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production

2018 · Alessandra Guidi, Fulvio Saccoccia, et al. · Parasites & Vectors · 24

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Synthesis of a hexahydropyrimido[1,2-a]azepine-2-carboxamide derivative useful as an HIV integrase inhibitor

2007 · Marco Ferrara, Benedetta Crescenzi, et al. · Tetrahedron Letters · 20

Novel Macrocyclic Inhibitors of Hepatitis C NS3/4A Protease Featuring a 2-Amino-1,3-thiazole as a P4 Carbamate Replacement

2009 · M. Emilia Di Francesco, Gabriella Dessole, et al. · Journal of Medicinal Chemistry · 19

Capped dipeptide α-Ketoacid inhibitors of the HCV NS3 protease

2002 · Emanuela Nizi, Uwe Koch, et al. · Bioorganic & Medicinal Chemistry Letters · 18

Solid phase synthesis of 2,6-disubstituted-4(3H)-pyrimidinones targeting HIV-1 reverse transcriptase

1998 · Emanuela Nizi, Maurizio Botta, et al. · Tetrahedron Letters · 18

Capped dipeptide phenethylamide inhibitors of the HCV NS3 protease

2004 · Emanuela Nizi, Uwe Koch, et al. · Bioorganic & Medicinal Chemistry Letters · 14

Dihydroxy-pyrimidine and N-methylpyrimidone HIV-integrase inhibitors: Improving cell based activity by the quaternarization of a chiral center

2009 · Emanuela Nizi, Maria Vittoria Orsale, et al. · Bioorganic & Medicinal Chemistry Letters · 12

Studies of metabolism and disposition of potent human immunodeficiency virus (HIV) integrase inhibitors using19F-NMR spectroscopy

2007 · E. Monteagudo, S. Pesci, et al. · Xenobiotica · 9

Phenyldihydroxypyrimidines as HCV NS5B RNA Dependent RNA Polymerase Inhibitors. Part I: Amides and Ureas

2005 · B. Crescenzi, M. Poma, et al. · Letters in Drug Design & Discovery · 7

Discovery of 4-((1-(1H-imidazol-2-yl)alkoxy)methyl)pyridines as a new class of Trypanosoma cruzi growth inhibitors

2020 · Simona Ponzi, Alberto Bresciani, et al. · Bioorganic & Medicinal Chemistry Letters · 1

ChemInform Abstract: Synthesis of a Hexahydropyrimido[1,2‐a]azepine‐2‐carboxamide Derivative (I) Useful as an HIV Integrase Inhibitor.

2008 · Marco Ferrara, Benedetta Crescenzi, et al. · ChemInform · 1

Discovery and Optimization of an mRNA Display Cyclic Peptide inhibitor of the IL1b/IL1R Interaction

2026 · Stefania Colarusso, Francesca Pavone, et al. · European Peptide Symposium (EPS)

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Works count: 25

Citation count: 1,740

H-index: 18

I10-index: 20