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Lakshmi Narasimham

Physico-chemical characterization of some beta blockers and anti-diabetic drugs - potentiometric and spectrophotometric pKa determination in different co-solvents
2011 · Lakshmi Narasimham, Vasant Dnyandeo Barhate · European Journal of Chemistry · 25
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Discovery of isoquinolinone and naphthyridinone-based inhibitors of poly(ADP-ribose) polymerase-1 (PARP1) as anticancer agents: Structure activity relationship and preclinical characterization
2020 · Navnath P. Karche, Mandar Bhonde, et al. · Bioorganic & Medicinal Chemistry · 15
Discovery of a Potent and Selective PI3Kδ Inhibitor (S)-2,4-Diamino-6-((1-(7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenyl-4H-quinolizin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile with Improved Pharmacokinetic Profile and Superior Efficacy in Hematological Cancer Models
2020 · Manojkumar R. Shukla, Sukanya Patra, et al. · Journal of Medicinal Chemistry · 13
Discovery and Characterization of Potent Pan-Genotypic HCV NS5A Inhibitors Containing Novel Tricyclic Central Core Leading to Clinical Candidate
2019 · Vidya Ramdas, Rashmi Talwar, et al. · Journal of Medicinal Chemistry · 12
Discovery of a Novel Potent and Selective Calcium Release-Activated Calcium Channel Inhibitor: 2,6-Difluoro-N-(2′-methyl-3′-(4-methyl-5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)-[1,1′-biphenyl]-4-yl)benzamide. Structure–Activity Relationship and Preclinical Characterization
2021 · Nilesh Raghunath Khedkar, Nageswara Rao Irlapatti, et al. · Journal of Medicinal Chemistry · 9
Discovery of LNP1892: A Precision Calcimimetic for the Treatment of Secondary Hyperparathyroidism
2023 · Manojkumar R. Shukla, Gayathri Sadasivam, et al. · Journal of Medicinal Chemistry · 7
Discovery and pre-clinical characterization of a selective PI3Kδ inhibitor, LL-00071210 in rheumatoid arthritis
2022 · Vijay Kanoje, Dilip Pandey, et al. · European Journal of Pharmacology · 6
Integrated Analytical Strategy for Determination of Nitrite and N-Nitrosoquinapril in Pharmaceutical Systems Using HPLC and LC–MS/MS
2026 · Prakash Ashok Deshinge, Srinivasarao Vaddadi, et al. · International Journal of Drug Delivery Technology
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Works count: 8
Citation count: 87
H-index: 6
I10-index: 4
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