Author

Michael J. Morrison

Observed names: M.J. Morrison, Michael J Morrison, Michael Morrison

Observed institutions: Wesleyan University, Amgen (United States), University of Dundee, Epizyme (United States), Amgen (United Kingdom), Evotec (United Kingdom), Massachusetts Institute of Technology

ORCID: 0000-0002-8948-1773

Observed ORCID: 0000-0002-8948-1773

OpenAlex ID: A5035229359

A quantitative analysis of kinase inhibitor selectivity

2008 · Mazen W Karaman, Sanna Herrgard, et al. · Nature Biotechnology · 2,446

Evolution of a Highly Selective and Potent 2-(Pyridin-2-yl)-1,3,5-triazine Tie-2 Kinase Inhibitor

2007 · Brian L. Hodous, Stephanie D. Geuns-Meyer, et al. · Journal of Medicinal Chemistry · 92

The Renaissance of Bacillosamine and Its Derivatives: Pathway Characterization and Implications in Pathogenicity

2014 · Michael J. Morrison, Barbara Imperiali · Biochemistry · 81

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Biochemical Characterization of the O-Linked Glycosylation Pathway in Neisseria gonorrhoeae Responsible for Biosynthesis of Protein Glycans Containing N,N′-Diacetylbacillosamine

2011 · Meredith D. Hartley, Michael J. Morrison, et al. · Biochemistry · 79

Novel 2,3-Dihydro-1,4-Benzoxazines as Potent and Orally Bioavailable Inhibitors of Tumor-Driven Angiogenesis

2008 · Daniel S. La, Julie Belzile, et al. · Journal of Medicinal Chemistry · 75

Novel 2-Aminopyrimidine Carbamates as Potent and Orally Active Inhibitors of Lck: Synthesis, SAR, and in Vivo Antiinflammatory Activity

2006 · Matthew W. Martin, John Newcomb, et al. · Journal of Medicinal Chemistry · 58

Discovery of a Potent, Selective, and Orally Bioavailable Pyridinyl-Pyrimidine Phthalazine Aurora Kinase Inhibitor

2010 · Victor J. Cee, Laurie B. Schenkel, et al. · Journal of Medicinal Chemistry · 38

Identification of a peptide inhibitor for the histone methyltransferase WHSC1

2018 · Michael J. Morrison, P. Ann Boriack-Sjodin, et al. · PLoS ONE · 37

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Synthesis, structural analysis, and SAR studies of triazine derivatives as potent, selective Tie-2 inhibitors

2007 · Brian L. Hodous, Stephanie D. Geuns-Meyer, et al. · Bioorganic & Medicinal Chemistry Letters · 32

Alkynylpyrimidine Amide Derivatives as Potent, Selective, and Orally Active Inhibitors of Tie-2 Kinase

2007 · Victor J. Cee, Brian K. Albrecht, et al. · Journal of Medicinal Chemistry · 29

Biosynthesis of UDP-N,N′-diacetylbacillosamine in Acinetobacter baumannii: Biochemical characterization and correlation to existing pathways

2013 · Michael J. Morrison, Barbara Imperiali · Archives of Biochemistry and Biophysics · 22

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Targeting Bacillosamine Biosynthesis in Bacterial Pathogens: Development of Inhibitors to a Bacterial Amino-Sugar Acetyltransferase from Campylobacter jejuni

2017 · Joris W. De Schutter, James P. Morrison, et al. · Journal of Medicinal Chemistry · 19

Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors

2011 · John L. Buchanan, John R. Newcomb, et al. · Bioorganic & Medicinal Chemistry Letters · 18

Biochemical Analysis and Structure Determination of Bacterial Acetyltransferases Responsible for the Biosynthesis of UDP-N,N′-Diacetylbacillosamine

2013 · Michael J. Morrison, Barbara Imperiali · Journal of Biological Chemistry · 14

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Inverse Acyl Phosph(on)ates: Substrates or Inhibitors of β-Lactam-Recognizing Enzymes?

2001 · Michael J. Morrison, Naixin Li, et al. · Bioorganic Chemistry · 11

Monitoring GAPDH activity and inhibition with cysteine-reactive chemical probes

2022 · Sarah E. Canarelli, Brooke M. Swalm, et al. · RSC Chemical Biology · 9

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Detection of an enzyme isomechanism by means of the kinetics of covalent inhibition

2021 · S.A. Adediran, Michael J. Morrison, et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 4

Elucidation of the pathways responsible for the biosynthesis of UDP-N,N'-diacetylbacillosamine in bacterial pathogens

2013 · Michael J. Morrison · DSpace@MIT (Massachusetts Institute of Technology) · 1

Acetyltransferase domain of PglB from Neisseria gonorrhoeae FA1090

2013 · M.J. Morrison, B. Imperiali · Worldwide Protein Data Bank

Acetyltransferase domain of PglB from Neisseria gonorrhoeae FA1090 in complex with acetyl coenzyme A

2013 · M.J. Morrison, B. Imperiali · Worldwide Protein Data Bank

Discovery of a potent, highly selective Tie-2 kinase inhibitor demonstrating in vivo efficacy, based on a novel pyridyl triazine scaffold.

2006 · Brian L. Hodous, Stephanie Geuns-Meyer, et al. · Cancer Research

Works count: 21

Citation count: 3,065

H-index: 14

I10-index: 15