Author

Keith H. Ansell

Observed names: K Ansell, K. Ansell, Keith Ansell

Institution: LifeArc

Observed institutions: LifeArc, Medical Research Council

OpenAlex ID: A5035686174

Subcellular Discharge of a Serine Protease Mediates Release of Invasive Malaria Parasites from Host Erythrocytes

2007 · Sharon Yeoh, Rebecca A. O'Donnell, et al. · Cell · 365

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A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission

2017 · David A. Baker, Lindsay B. Stewart, et al. · Nature Communications · 171

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High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy

2014 · M Rossi, B Rotblat, et al. · Cell Death and Disease · 134

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Optimization of primers for cloning libraries of mouse immunoglobulin genes using the polymerase chain reaction

1993 · Catherine A. Kettleborough, José Saldanha, et al. · European Journal of Immunology · 80

Inhibition of Papillomavirus Protein Function in Cervical Cancer Cells by Intrabody Targeting

2005 · Heather Griffin, Robert Elston, et al. · Journal of Molecular Biology · 79

Discovery of Plasmodium vivaxN-Myristoyltransferase Inhibitors: Screening, Synthesis, and Structural Characterization of their Binding Mode

2012 · Victor Goncalves, James A. Brannigan, et al. · Journal of Medicinal Chemistry · 77

Monocyclic β-Lactams Are Selective, Mechanism-Based Inhibitors of Rhomboid Intramembrane Proteases

2010 · Olivier A. Pierrat, Kvido Strisovsky, et al. · ACS Chemical Biology · 64

Substituted imidazopyridazines are potent and selective inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1)

2013 · Timothy M. Chapman, Simon A. Osborne, et al. · Bioorganic & Medicinal Chemistry Letters · 55

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Imidazopyridazine Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinase 1 Also Target Cyclic GMP-Dependent Protein Kinase and Heat Shock Protein 90 To Kill the Parasite at Different Stages of Intracellular Development

2015 · Judith L. Green, Robert W. Moon, et al. · Antimicrobial Agents and Chemotherapy · 53

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Optimization of an Imidazopyridazine Series of Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinase 1 (PfCDPK1)

2014 · Timothy M. Chapman, Simon A. Osborne, et al. · Journal of Medicinal Chemistry · 53

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Itch inhibition regulates chemosensitivity in vitro

2007 · T.M. Hansen, M. Rossi, et al. · Biochemical and Biophysical Research Communications · 44

Synthesis and in vitro evaluation of imidazopyridazines as novel inhibitors of the malarial kinase PfPK7

2008 · Nathalie Bouloc, Jonathan M. Large, et al. · Bioorganic & Medicinal Chemistry Letters · 41

Imidazopyridazines as potent inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1): Preparation and evaluation of pyrazole linked analogues

2013 · Jonathan M. Large, Simon A. Osborne, et al. · Bioorganic & Medicinal Chemistry Letters · 39

Isolation of tumor cell‐specific single‐chain Fv from immunized mice using phage‐antibody libraries and the re‐construction of whole antibodies from these antibody fragments

1994 · Catherine A. Kettleborough, Keith H. Ansell, et al. · European Journal of Immunology · 36

Biochemical and Antiparasitic Properties of Inhibitors of the Plasmodium falciparum Calcium-Dependent Protein Kinase PfCDPK1

2014 · Keith H. Ansell, Hayley M. Jones, et al. · Antimicrobial Agents and Chemotherapy · 34

Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG)

2018 · Denise J. Tsagris, Kristian Birchall, et al. · Bioorganic & Medicinal Chemistry Letters · 25

Potent inhibitors of malarial P. Falciparum protein kinase G: Improving the cell activity of a series of imidazopyridines

2018 · Jonathan M. Large, Kristian Birchall, et al. · Bioorganic & Medicinal Chemistry Letters · 20

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Potent bicyclic inhibitors of malarial cGMP-dependent protein kinase: approaches to combining improvements in cell potency, selectivity and structural novelty

2019 · Jonathan M. Large, Kristian Birchall, et al. · Bioorganic & Medicinal Chemistry Letters · 14

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Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors

2023 · Andrew J. Wilkinson, Nicola Ooi, et al. · Bioorganic & Medicinal Chemistry Letters · 9

Corrigendum to “Imidazopyridazines as potent inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1): Preparation and evaluation of pyrazole linked analogues” [Bioorg. Med. Chem. Lett. 23 (2013) 6019–6024]

2013 · Jonathan M. Large, Simon A. Osborne, et al. · Bioorganic & Medicinal Chemistry Letters · 1

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A Protein from the Salivary Glands of the Giant Amazon Leech with High Sequence Homology to a Nicotinic Acetylcholine Receptor Subunit

1999 · Sancha Salgueiro, Susan Potts, et al. · Zeitschrift für Naturforschung C · 1

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Works count: 21

Citation count: 1,395

H-index: 17

I10-index: 18