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Pranali Ravikumar
Observed institutions:
Fred Hutch Cancer Center,
University of Pennsylvania
ORCID:
0000-0003-3989-4251
Observed ORCID:
0000-0003-3989-4251
OpenAlex ID:
A5035894670
Ionizable Lipid Nanoparticle-Mediated mRNA Delivery for Human CAR T Cell Engineering
2020
·
Margaret M. Billingsley
, Nathan Singh
, et al.
·
Nano Letters
·
626
Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction
2020
·
Nathan Singh
, Yong Gu Lee
, et al.
·
Cancer Discovery
·
294
Safety and efficacy of rozanolixizumab in patients with generalised myasthenia gravis (MycarinG): a randomised, double-blind, placebo-controlled, adaptive phase 3 study
2023
·
Vera Bril
, Vera Bril
, et al.
·
The Lancet Neurology
·
293
Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells
2021
·
Nathan Singh
, Noelle V. Frey
, et al.
·
Nature Medicine
·
196
Deletion of the inhibitory co-receptor CTLA-4 enhances and invigorates chimeric antigen receptor T cells
2023
·
Sangya Agarwal
, M. Angela Aznar
, et al.
·
Immunity
·
185
Potentiating adoptive cell therapy using synthetic IL-9 receptors
2022
·
Anusha Kalbasi
, Mikko Siurala
, et al.
·
Nature
·
121
PDF
A Fas-4-1BB fusion protein converts a death to a pro-survival signal and enhances T cell therapy
2020
·
Shannon K. Oda
, Kristin G. Anderson
, et al.
·
The Journal of Experimental Medicine
·
61
Single Chain Variable Fragment Linker Length Regulates CAR Biology and T Cell Efficacy
2019
·
Nathan Singh
, Noelle V. Frey
, et al.
·
Blood
·
18
Abstract 5571: Disruption of cell-intrinsic checkpoint regulator CTLA-4 in CD19 directed CAR T cells provides clinical efficacy in CLL patients
2022
·
Sangya Agarwal
, Angela Aznar Gomez
, et al.
·
Cancer Research
·
3
Publisher Correction: Potentiating adoptive cell therapy using synthetic IL-9 receptors
2022
·
Anusha Kalbasi
, Mikko Siurala
, et al.
·
Nature
·
2
PDF
CAR T Cell Cytotoxicity Is Dependent on Death Receptor-Driven Apoptosis
2018
·
Nathan Singh
, Olga Shestova
, et al.
·
Blood
·
2
175 A Fas-4–1BB immunomodulatory fusion protein converts a pro-death to a pro-survival signal, enhancing T cell function and efficacy of adoptive cell therapy in murine models of AML and pancreatic cancer
2020
·
Shannon Oda
, Kristin Anderson
, et al.
·
Regular and Young Investigator Award Abstracts
·
1
Impaired tumor death receptor signaling drives resistance to CAR T cell therapy
2019
·
Nathan Singh
, Olga Shestova
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
1
PDF
Cheating death: a Fas-41BB immunomodulatory fusion protein obviates a death signal to enhance T cell function and adoptive therapy targeting leukemia and solid tumors
2018
·
Shannon K Oda
, Kristin G Anderson
, et al.
·
The Journal of Immunology
·
1
Tu1102 SINGLE ADMINISTRATION OF EP-104GI IN RESOLVE, A PHASE 1B/2 TRIAL IN EOSINOPHILIC ESOPHAGITIS, IMPROVES ENDOSCOPIC FEATURES OF INFLAMMATION AND FIBROSIS OVER 36 WEEKS
2026
·
Nirmala Gonsalves
, Nam Q. Nguyen
, et al.
·
Gastroenterology
Tu1102 SINGLE ADMINISTRATION OF EP-104GI IN RESOLVE, A PHASE 1B/2 TRIAL IN EOSINOPHILIC ESOPHAGITIS, IMPROVES ENDOSCOPIC FEATURES OF INFLAMMATION AND FIBROSIS OVER 36 WEEKS
2026
·
Nirmala Gonsalves
, Nam Q. Nguyen
, et al.
·
Gastrointestinal Endoscopy
S891 Results From Dose Escalation Cohorts 1-6 of RESOLVE, an Ongoing Phase 1b/2a Study of EP-104GI (Long-Acting Fluticasone Propionate Injectable Suspension) for Eosinophilic Esophagitis
2025
·
Amanda Malone
, James Helliwell
, et al.
·
The American Journal of Gastroenterology
Data from Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction
2023
·
Nathan Singh
, Yong Gu Lee
, et al.
Table S2 from Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction
2023
·
Nathan Singh
, Yong Gu Lee
, et al.
Figure S2 from Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction
2023
·
Nathan Singh
, Yong Gu Lee
, et al.
Figure S1 from Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction
2023
·
Nathan Singh
, Yong Gu Lee
, et al.
Figure S5 from Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction
2023
·
Nathan Singh
, Yong Gu Lee
, et al.
Table S3 from Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction
2023
·
Nathan Singh
, Yong Gu Lee
, et al.
Figure S3 from Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction
2023
·
Nathan Singh
, Yong Gu Lee
, et al.
Figure S7 from Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction
2023
·
Nathan Singh
, Yong Gu Lee
, et al.
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Works count:
43
Citation count:
1,800
H-index:
8
I10-index:
8
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