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Duane E. DeMong

Observed names: DeMong, Duane E., Demong D.E, Duane DeMong, Duane E DeMong, Duane E. Demong, Duane E. Demong*
ORCID: 0009-0007-0644-2677
Observed ORCID: 0009-0007-0644-2677
OpenAlex ID: A5038141014
MLi-2, a Potent, Selective, and Centrally Active Compound for Exploring the Therapeutic Potential and Safety of LRRK2 Kinase Inhibition
2015 · Matthew J. Fell, Christian Mirescu, et al. · Journal of Pharmacology and Experimental Therapeutics · 310
A Novel Carbohydrate-Glycosphingolipid Interaction between a β-(1–3)-Glucan Immunomodulator, PGG-glucan, and Lactosylceramide of Human Leukocytes
1998 · Janet W. Zimmerman, Johanna Lindermuth, et al. · Journal of Biological Chemistry · 223
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Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity
2017 · Jack D. Scott, Duane E. DeMong, et al. · Journal of Medicinal Chemistry · 149
Asymmetric Synthesis of (2S,3R)-Capreomycidine and the Total Synthesis of Capreomycin IB
2003 · Duane E. DeMong, Robert M. Williams · Journal of the American Chemical Society · 72
A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins
2022 · Anna Fryszkowska, Chihui An, et al. · Science · 56
The asymmetric synthesis of (2 S ,3 R )-capreomycidine
2001 · Duane E DeMong, Robert M Williams · Tetrahedron Letters · 33
Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1 H -Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease
2022 · David A. Candito, Vladimir Simov, et al. · Journal of Medicinal Chemistry · 31
Synthesis, Structure−Activity Relationship and in Vivo Antiinflammatory Efficacy of Substituted Dipiperidines as CCR2 Antagonists
2007 · Mingde Xia, Cuifen Hou, et al. · Journal of Medicinal Chemistry · 25
The Discovery ofN-((2H-Tetrazol-5-yl)methyl)-4-((R)-1-((5r,8R)-8-(tert-butyl)-3-(3,5-dichlorophenyl)-2-oxo-1,4-diazaspiro[4.5]dec-3-en-1-yl)-4,4-dimethylpentyl)benzamide (SCH 900822): A Potent and Selective Glucagon Receptor Antagonist
2014 · Duane DeMong, Xing Dai, et al. · Journal of Medicinal Chemistry · 21
Synthesis and structure–activity relationship of 7-azaindole piperidine derivatives as CCR2 antagonists
2008 · Mingde Xia, Cuifen Hou, et al. · Bioorganic & Medicinal Chemistry Letters · 16
An efficient asymmetric synthesis of (2S,3S)- and (2R,3R)-β-hydroxyornithine
2001 · Duane E DeMong, Robert M Williams · Tetrahedron Letters · 16
Asymmetric Synthesis of N ‐ tert ‐Butoxycarbonyl α‐Amino Acids. Synthesis of (5 S ,6 R )‐4‐ tert ‐Butoxycarbonyl‐5,6‐Diphenylmorpholin‐2‐one
2003 · Robert M. Williams, Peter J. Sinclair, et al. · Organic Syntheses · 15
Substituted dipiperidine alcohols as potent CCR2 antagonists
2008 · Mingde Xia, Cuifen Hou, et al. · Bioorganic & Medicinal Chemistry Letters · 14
A Novel Method for the Preparation of 4-Arylimidazolones
2013 · Duane E. DeMong, Irene Ng, et al. · Organic Letters · 12
The first asymmetric synthesis of (2S)- and (2R)-amino-3,3-dimethoxypropanoic acid
2002 · Duane E. DeMong, Robert M. Williams · Tetrahedron Letters · 12
Structure–Activity Relationship of Novel and Selective Biaryl-Chroman GPR40 AgoPAMs
2018 · Helen Y. Chen, Christopher W. Plummer, et al. · ACS Medicinal Chemistry Letters · 10
Synthesis and biological evaluation of phenyl piperidine derivatives as CCR2 antagonists
2007 · Mingde Xia, Cuifen Hou, et al. · Bioorganic & Medicinal Chemistry Letters · 10
Asymmetric Synthesis of (+)-Hypusine
2001 · Rajendra P. Jain, Brian K. Albrecht, et al. · Organic Letters · 10
Glucagon Receptor Antagonists for Type II Diabetes
2008 · Duane E. DeMong, Michael W. Miller, et al. · Annual reports in medicinal chemistry · 8
Efficient Asymmetric Synthesis of N ‐ tert ‐Butoxycarbonyl α‐Aminoacids Using 4‐ tert ‐Butoxycarbonyl‐5,6‐Diphenylmorpholin‐2‐one: ( R )‐( N ‐ tert ‐Butoxycarbonyl)Allylglycine
2003 · Robert M. Williams, Peter J. Sinclair, et al. · Organic Syntheses · 5
Chapter 15. Glucagon Receptor Antagonists in Development
2012 · Duane E. Demong*, M. W. Miller · RSC drug discovery/RSC drug discovery series · 4
Discovery of MK-1088 as a Potent A 2A /A 2B Adenosine Receptor Dual-Antagonist for Cancer Immunotherapy
2026 · Yonglian Zhang, Elisabeth Hennessy, et al. · Journal of Medicinal Chemistry · 2
Asymmetric Synthesis of (2S,3R)‐Capreomycidine and the Total Synthesis of Capreomycin IB.
2003 · Duane E. DeMong, Robert M. Williams · ChemInform · 2
Discovery of Potent and Selective Benzothiophene Difluoromethyl Phosphonate (DFMP) PTPN2/N1-Dual Inhibitors
2026 · Xiao Mei Zheng, David A. Candito, et al. · Journal of Medicinal Chemistry · 1
Nickel-Catalyzed Reductive Coupling: A Practical Approach for the Synthesis of Aryl-Substituted 1,3-Cyclobutanes in Medicinal Chemistry
2025 · Lorena Rico, Zachary G. Brill, et al. · Organic Letters · 1
Works count: 37
Citation count: 1,058
H-index: 13
I10-index: 18
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