Author

Elizabeth A. Witten

Observed names: Elizabeth Witten, Witten, Elizabeth

Institution: Dana-Farber Cancer Institute

Observed institutions: Harvard University, Dana-Farber Cancer Institute

ORCID: 0000-0002-9267-4066

Observed ORCID: 0000-0002-9267-4066

OpenAlex ID: A5039708346

Regulation of the Saccharomyces cerevisiae HOG1 Mitogen-Activated Protein Kinase by the PTP2 and PTP3 Protein Tyrosine Phosphatases

1997 · Susannah M. Wurgler-Murphy, Tatsuya Maeda, et al. · Molecular and Cellular Biology · 265

Regulation of MTK1/MEKK4 Kinase Activity by Its N-Terminal Autoinhibitory Domain and GADD45 Binding

2002 · Hiroaki Mita, Junichiro Tsutsui, et al. · Molecular and Cellular Biology · 154

PDF

Requirement of STE50 for Osmostress-Induced Activation of the STE11 Mitogen-Activated Protein Kinase Kinase Kinase in the High-Osmolarity Glycerol Response Pathway

1998 · Francesc Posas, Elizabeth A. Witten, et al. · Molecular and Cellular Biology · 137

A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation

2021 · Gregory Lazarian, Shanye Yin, et al. · Cancer Cell · 55

PDF

CD40L-Tri, a novel formulation of recombinant human CD40L that effectively activates B cells

2012 · Masayasu Naito, Ursula Hainz, et al. · Cancer Immunology Immunotherapy · 38

PDF

Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma

2022 · Patrick C. Lee, Susan Klaeger, et al. · Journal of Clinical Investigation · 36

PDF

In Vivo Modeling of CLL Transformation to Richter Syndrome Reveals Convergent Evolutionary Paths and Therapeutic Vulnerabilities

2022 · Elisa ten Hacken, Tomasz Sewastianik, et al. · Blood Cancer Discovery · 29

The heterogeneity of human antibody responses to vaccinia virus revealed through use of focused protein arrays

2009 · Jonathan S. Duke-Cohan, Kristin Wollenick, et al. · Vaccine · 25

Activation of Notch and Myc Signaling via B-cell–Restricted Depletion of Dnmt3a Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia

2021 · Anat Biran, Shanye Yin, et al. · Cancer Research · 21

Loss-of-function lesions impact B-cell development and fitness but are insufficient to drive CLL in mouse models

2022 · Elisa ten Hacken, Shanye Yin, et al. · Blood Advances · 5

PDF

RPS15 and TP53 Co-Mutation Drives B Cell Malignancy through Altered Translation and MYC Activation in a Murine Model

2020 · Catherine Gutierrez, Tamara Ouspenskaia, et al. · Blood · 4

Immuno-Genetic Changes Underlie Response to Immune Checkpoint Blockade Therapy in Richter's Syndrome Mouse Models

2022 · Elisa Ten Hacken, Gabriela Brunsting Hoffmann, et al. · Blood · 3

Mutant ribosomal protein RPS15 drives B cell malignancy through oxidative stress and genomic instability

2026 · Catherine Gutierrez, Marwan Kwok, et al. · Nature Communications · 2

Impaired Response to Oxidative DNA Damage Underlies Genomic Instability in B-Cell Leukemia Driven By RPS15 Mutation

2024 · Marwan Kwok, Catherine Gutierrez, et al. · Blood · 2

Dissecting Richter's Syndrome in a Multiplexed CRISPR-Based Mouse Model Reveals Key Changes in MYC, Interferon and BCR Signaling Underlying Transformation

2021 · Elisa Ten Hacken, Shanye Yin, et al. · Blood · 2

Multiplexed CRISPR In Vivo Editing of CLL Loss-of-Function Lesions Models Transformation of Chronic Lymphocytic Leukemia into Richter's Syndrome

2020 · Elisa Ten Hacken, Tomasz Sewastianik, et al. · Blood · 1

B Cell Restricted Expression of Mutated IKZF3 modulates BCR Signaling and Homing Pathways in a Mouse Model of CLL

2019 · Gregory Lazarian, Shanye Yin, et al. · Blood · 1

Supplementary Figures from In Vivo Modeling of CLL Transformation to Richter Syndrome Reveals Convergent Evolutionary Paths and Therapeutic Vulnerabilities

2025 · Elisa ten Hacken, Tomasz Sewastianik, et al.

Supplementary Tables from In Vivo Modeling of CLL Transformation to Richter Syndrome Reveals Convergent Evolutionary Paths and Therapeutic Vulnerabilities

2025 · Elisa ten Hacken, Tomasz Sewastianik, et al.

Data from In Vivo Modeling of CLL Transformation to Richter Syndrome Reveals Convergent Evolutionary Paths and Therapeutic Vulnerabilities