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Kerensa Broersen

Alzheimer’s Disease: Treatment Strategies and Their Limitations
2022 · Elodie Passeri, Kamil Elkhoury, et al. · International Journal of Molecular Sciences · 609
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Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio
2010 · Inna Kuperstein, Kerensa Broersen, et al. · The EMBO Journal · 532
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The mechanism of γ‐Secretase dysfunction in familial Alzheimer disease
2012 · Lucía Chávez‐Gutiérrez, Leen Bammens, et al. · The EMBO Journal · 495
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Structural Basis for Increased Toxicity of Pathological Aβ42:Aβ40 Ratios in Alzheimer Disease
2011 · Kris Pauwels, Thomas L. Williams, et al. · Journal of Biological Chemistry · 253
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Molecular Mechanisms and Genetics of Oxidative Stress in Alzheimer’s Disease
2019 · Federica Cioffi, Rayan Hassan Ibrahim Adam, et al. · Journal of Alzheimer s Disease · 205
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The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?
2010 · Kerensa Broersen, Frederic Rousseau, et al. · Alzheimer s Research & Therapy · 168
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A standardized and biocompatible preparation of aggregate-free amyloid beta peptide for biophysical and biological studies of Alzheimer's disease
2011 · K. Broersen, W. Jonckheere, et al. · Protein Engineering Design and Selection · 126
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Organoids-on-a-chip: microfluidic technology enables culture of organoids with enhanced tissue function and potential for disease modeling
2025 · Lito Papamichail, Lena S. Koch, et al. · Frontiers in Bioengineering and Biotechnology · 120
Amyloid precursor protein mutation E682K at the alternative β‐secretase cleavage β′‐site increases Aβ generation†
2011 · Lujia Zhou, Nathalie Brouwers, et al. · EMBO Molecular Medicine · 117
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Glycoforms of β‐lactoglobulin with improved thermostability and preserved structural packing
2004 · Kerensa Broersen, Alphons G. J. Voragen, et al. · Biotechnology and Bioengineering · 102
Transient dynamics of Aβ contribute to toxicity in Alzheimer’s disease
2014 · E. Hubin, N. A. J. van Nuland, et al. · Cellular and Molecular Life Sciences · 101
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Mechanism of arachidonic acid action on syntaxin–Munc18
2007 · Emma Connell, Frédéric Darios, et al. · EMBO Reports · 94
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Optimized Triton X-114 assisted lipopolysaccharide (LPS) removal method reveals the immunomodulatory effect of food proteins
2017 · Malgorzata Teodorowicz, Olaf Perdijk, et al. · PLoS ONE · 92
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α-Synuclein Adopts an α-Helical Conformation in the Presence of Polyunsaturated Fatty Acids To Hinder Micelle Formation
2006 · Kerensa Broersen, Daan van den Brink, et al. · Biochemistry · 92
Multiplexed blood–brain barrier organ-on-chip
2020 · M. Zakharova, M. A. Palma do Carmo, et al. · Lab on a Chip · 81
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A comparative analysis of the aggregation behavior of amyloid‐β peptide variants
2012 · Annelies Vandersteen, Ellen Hubin, et al. · FEBS Letters · 74
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Apolipoprotein E associated with reconstituted high‐density lipoprotein‐like particles is protected from aggregation
2019 · Ellen Hubin, Philip B. Verghese, et al. · FEBS Letters · 73
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A Review of Oxidative Stress Products and Related Genes in Early Alzheimer’s Disease
2021 · Federica Cioffi, Rayan Hassan Ibrahim Adam, et al. · Journal of Alzheimer s Disease · 71
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Do Sulfhydryl Groups Affect Aggregation and Gelation Properties of Ovalbumin?
2006 · Kerensa Broersen, Annemarie M. M. Van Teeffelen, et al. · Journal of Agricultural and Food Chemistry · 71
Mechanistic Insights in Glycation-Induced Protein Aggregation
2014 · Miquel Adrover, Laura Mariño, et al. · Biomacromolecules · 67
Milk Processing Affects Structure, Bioavailability and Immunogenicity of β-lactoglobulin
2020 · Kerensa Broersen · Foods · 65
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Glucosylation of β‐lactoglobulin lowers the heat capacity change of unfolding; a unique way to affect protein thermodynamics
2005 · Annemarie M.M. Van Teeffelen, Kerensa Broersen, et al. · Protein Science · 55
Cross-seeding of alpha-synuclein aggregation by amyloid fibrils of food proteins
2021 · Jonathan Vaneyck, Ine Segers-Nolten, et al. · Journal of Biological Chemistry · 50
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Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo[c]phenanthridine and berberine-based compounds on β-amyloid aggregation
2020 · Daniela Marasco, Caterina Vicidomini, et al. · Chemico-Biological Interactions · 47
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Molecular Plasticity Regulates Oligomerization and Cytotoxicity of the Multipeptide-length Amyloid-β Peptide Pool
2012 · Annelies Vandersteen, Marcelo F. Masman, et al. · Journal of Biological Chemistry · 44
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Works count: 79
Citation count: 4,284
H-index: 31
I10-index: 43
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