Get started
Author

Deanna M. Langfitt

Observed names: D. Langfitt, Deanna Langfitt, Deanna M Langfitt, Langfitt, Deanna
ORCID: 0000-0003-0941-5360
Observed ORCID: 0000-0003-0941-5360
OpenAlex ID: A5040095629
Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity
2021 · Brooke Prinzing, Caitlin C. Zebley, et al. · Science Translational Medicine · 347
Distinct Hodgkin lymphoma subtypes defined by noninvasive genomic profiling
2023 · Stefan K. Alig, Mohammad Shahrokh Esfahani, et al. · Nature · 111
PDF
CD19-CAR T cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia
2021 · Caitlin C. Zebley, Charmaine Brown, et al. · Cell Reports · 106
CAR T cells redirected to cell surface GRP78 display robust anti-acute myeloid leukemia activity and do not target hematopoietic progenitor cells
2022 · Nikhil Hebbar, Rebecca Epperly, et al. · Nature Communications · 83
PDF
A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function
2021 · Shannon Lange, Laurens G.L. Sand, et al. · Cancer Discovery · 68
Engineering naturally occurring CD7− T cells for the immunotherapy of hematological malignancies
2022 · Abdullah Freiwan, Jaquelyn T. Zoine, et al. · Blood · 66
PDF
Preferential expansion of CD8+ CD19-CAR T cells postinfusion and the role of disease burden on outcome in pediatric B-ALL
2022 · Aimee C. Talleur, Amr Qudeimat, et al. · Blood Advances · 65
Common Trajectories of Highly Effective CD19-Specific CAR T Cells Identified by Endogenous T-cell Receptor Lineages
2022 · Taylor L. Wilson, Hyunjin Kim, et al. · Cancer Discovery · 60
Safety and Anti-Leukemic Activity of CD123-CAR T Cells in Pediatric Patients with AML: Preliminary Results from a Phase 1 Trial
2022 · Swati Naik, Renee M. Madden, et al. · Blood · 54
Modular chimeric cytokine receptors with leucine zippers enhance the antitumour activity of CAR T cells via JAK/STAT signalling
2023 · Matthew Bell, Shannon Lange, et al. · Nature Biomedical Engineering · 47
PDF
Antitumor Effects of CAR T Cells Redirected to the EDB Splice Variant of Fibronectin
2020 · Jessica Wagner, Elizabeth Wickman, et al. · Cancer Immunology Research · 46
PDF
IL-18R supported CAR T cells targeting oncofetal tenascin C for the immunotherapy of pediatric sarcoma and brain tumors
2024 · Elizabeth Wickman, Shannon Lange, et al. · Journal for ImmunoTherapy of Cancer · 27
PDF
CAR T-cell Design-dependent Remodeling of the Brain Tumor Immune Microenvironment Modulates Tumor-associated Macrophages and Anti-glioma Activity
2023 · Dalia Haydar, Jorge Ibañez-Vega, et al. · Cancer Research Communications · 26
PDF
Peptide-scFv antigen recognition domains effectively confer CAR T cell multiantigen specificity
2024 · Jaquelyn T. Zoine, Kalyan Immadisetty, et al. · Cell Reports Medicine · 24
Memory T-cell enriched haploidentical transplantation with NK cell addback results in promising long-term outcomes: a phase II trial
2024 · Swati Naik, Ying Li, et al. · Journal of Hematology & Oncology · 16
CD123-CAR T Cells Manufactured in the Presence of Dasatinib Induce High Grade CRS and/or IEC-HS without Improving Efficacy in Pediatric Patients with Recurrent/Refractory Leukemia
2024 · Swati Naik, Madden Renee, et al. · Blood · 12
PDF
B7-H3 CAR T Cells Are Effective against Ependymomas but Limited by Tumor Size and Immune Response
2025 · Sanya Mehta, Siri Ippagunta, et al. · Clinical Cancer Research · 10
PDF
Integrome signatures of lentiviral gene therapy for SCID-X1 patients
2023 · Koon-Kiu Yan, Jose Condori, et al. · Science Advances · 9
Genetic alteration of SJ293TS cells and modification of serum-free media enhances lentiviral vector production
2024 · Matthew Bauler, Francesca Ferrara, et al. · Molecular Therapy — Methods & Clinical Development · 8
De novo DNA methylation programs regulate CAR T-cell exhaustion
2020 · Caitlin C Zebley, Christopher T Petersen, et al. · The Journal of Immunology · 5
Resistance to Yersinia pestis Infection Decreases with Age in B10.T(6R) Mice
2011 · Nathaniel D. Lambert, Deanna M. Langfitt, et al. · Infection and Immunity · 5
PDF
Ctim-15. Locoregional Administration of B7-h3-car T Cells Expressing 41bb Ligand for Pediatric Patients With Primary Cns Tumors: Preliminary Results From a Phase I Study
2024 · Kelsey C Bertrand, Anna Kostecka, et al. · Neuro-Oncology · 4
PDF
Autologous CD19-CAR T-Cells for the Treatment of Acute Lymphoblastic Leukemia in Pediatric and Young Adult Patients: An initial Report from an Institutional Phase I/II Study
2019 · Aimee Talleur, Amr Qudeimat, et al. · Clinical Lymphoma Myeloma & Leukemia · 3
Targeting Regnase-1 unleashes CAR T cell antitumor activity for osteosarcoma and creates a proinflammatory tumor microenvironment
2025 · Adeleye O. Adeshakin, Hao Shi, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
Modulation of cytokeratin and cytokine/chemokine expression following influenza virus infection of differentiated human tonsillar epithelial cells
2025 · S. Scott Perry, David C. Brice, et al. · Journal of Virology · 2
Works count: 157
Citation count: 1,219
H-index: 15
I10-index: 17
Year
Topic
Type