Author

Yusuke Oka

Institution: Taisho Pharmaceutical (Japan)

Observed institutions: Taisho Pharmaceutical (Japan), Tokyo University of Pharmacy and Life Sciences, Showa Pharmaceutical University

ORCID: 0000-0002-7864-061X

Observed ORCID: 0000-0002-7864-061X

OpenAlex ID: A5040320730

Discovery and optimization of a series of 2-aminothiazole-oxazoles as potent phosphoinositide 3-kinase γ inhibitors

2012 · Yusuke Oka, Tetsuya Yabuuchi, et al. · Bioorganic & Medicinal Chemistry Letters · 26

Discovery of N-{5-[3-(3-hydroxypiperidin-1-yl)-1,2,4-oxadiazol-5-yl]-4-methyl-1,3-thiazol-2-yl}acetamide (TASP0415914) as an orally potent phosphoinositide 3-kinase γ inhibitor for the treatment of inflammatory diseases

2013 · Yusuke Oka, Tetsuya Yabuuchi, et al. · Bioorganic & Medicinal Chemistry · 21

Palladium-Catalyzed Reaction of Acylzirconocene Chloride and Stereoselective Formation of Bicyclo[3.3.0] Compounds

2002 · Yuji Hanzawa, Masaya Yabe, et al. · Organic Letters · 21

Cyclization/acylation reactions by nickel-catalyzed reactions of 1,6-ynal and 1,6-enyne derivatives with acylzirconocene chloride

2006 · Akio Saito, Yusuke Oka, et al. · Tetrahedron Letters · 20

Ring-fused pyrazole derivatives as potent inhibitors of lymphocyte-specific kinase (Lck): Structure, synthesis, and SAR

2009 · Tetsuo Takayama, Hiroki Umemiya, et al. · Bioorganic & Medicinal Chemistry Letters · 16

Discovery of Highly Potent and Selective Matrix Metalloproteinase-7 Inhibitors by Hybridizing the S1′ Subsite Binder with Short Peptides

2022 · Hideaki Tabuse, Kumi Abe-Sato, et al. · Journal of Medicinal Chemistry · 12

Structure-Based Optimization and Biological Evaluation of Potent and Selective MMP-7 Inhibitors for Kidney Fibrosis

2023 · Kumi Abe-Sato, Hideaki Tabuse, et al. · Journal of Medicinal Chemistry · 7

Acylzirconocene chloride: Formation of carbocycles by palladium-catalyzed cascade reaction

2007 · Yuji Hanzawa, Yusuke Oka, et al. · Journal of Organometallic Chemistry · 7

A CONVENIENT SYNTHESIS OF 2-MERCAPTO-OXAZOLES VIA β-KETOAZIDE AND ITS APPLICATION TO A KEY INTERMEDIATE OF PI3Kγ INHIBITORS

2013 · Yusuke Oka, Tetsuya Yabuuchi, et al. · Heterocycles · 4

Discovery of TP0628103: A Highly Potent and Selective MMP-7 Inhibitor with Reduced OATP-Mediated Clearance Designed by Shifting Isoelectric Points

2024 · Yusuke Oka, Kumi Abe-Sato, et al. · Journal of Medicinal Chemistry · 3

ChemInform Abstract: A Convenient Synthesis of 2‐Mercapto‐oxazoles via β‐Ketoazide and Its Application to a Key Intermediate of PI3Kγ Inhibitors.

2014 · Yusuke Oka, Tetsuya Yabuuchi, et al. · ChemInform

ChemInform Abstract: Acylzirconocene Chloride: Formation of Carbocycles by Palladium‐Catalyzed Cascade Reaction.

2008 · Yuji Hanzawa, Yusuke Oka, et al. · ChemInform

Cyclization/Acylation Reactions by Nickel‐Catalyzed Reactions of 1,6‐Ynal and 1,6‐Enyne Derivatives with Acylzirconocene Chloride.

2006 · Akio Saito, Yusuke Oka, et al. · ChemInform

Palladium‐Catalyzed Reaction of Acylzirconocene Chloride and Stereoselective Formation of Bicyclo[3.3.0] Compounds.

2003 · Yuji Hanzawa, Masaya Yabe, et al. · ChemInform

Works count: 14

Citation count: 137

H-index: 7

I10-index: 6