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Chuck T. Chen

Observed names: Chuck Chen, Chuck T Chen, Chuck Tzu‐Huan Chen
ORCID: 0000-0002-1099-4198
Observed ORCID: 0000-0002-1099-4198
OpenAlex ID: A5040539181
Diffusion of docosahexaenoic and eicosapentaenoic acids through the blood–brain barrier: An in situ cerebral perfusion study
2009 · Melissa Ouellet, Vincent Emond, et al. · Neurochemistry International · 227
Regulation of brain polyunsaturated fatty acid uptake and turnover
2008 · Chuck T. Chen, Joshua T. Green, et al. · Prostaglandins Leukotrienes and Essential Fatty Acids · 171
Rapid β-oxidation of eicosapentaenoic acid in mouse brain: An in situ study
2009 · Chuck T. Chen, Zhen Liu, et al. · Prostaglandins Leukotrienes and Essential Fatty Acids · 161
Plasma non-esterified docosahexaenoic acid is the major pool supplying the brain
2015 · Chuck T. Chen, Alex P. Kitson, et al. · Scientific Reports · 135
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β-oxidation and rapid metabolism, but not uptake regulate brain eicosapentaenoic acid levels
2014 · Chuck T. Chen, Richard P. Bazinet · Prostaglandins Leukotrienes and Essential Fatty Acids · 110
Wnt signaling activates MFSD2A to suppress vascular endothelial transcytosis and maintain blood-retinal barrier
2020 · Zhongxiao Wang, Chi-Hsiu Liu, et al. · Science Advances · 107
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Effect of dietary docosahexaenoic acid (DHA) in phospholipids or triglycerides on brain DHA uptake and accretion
2016 · Alex P. Kitson, Adam H. Metherel, et al. · The Journal of Nutritional Biochemistry · 106
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The low levels of eicosapentaenoic acid in rat brain phospholipids are maintained via multiple redundant mechanisms
2013 · Chuck T. Chen, Anthony F. Domenichiello, et al. · Journal of Lipid Research · 105
Whole body synthesis rates of DHA from α-linolenic acid are greater than brain DHA accretion and uptake rates in adult rats
2013 · Anthony F. Domenichiello, Chuck T. Chen, et al. · Journal of Lipid Research · 103
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The low density lipoprotein receptor is not necessary for maintaining mouse brain polyunsaturated fatty acid concentrations
2007 · Chuck T. Chen, David W.L. Ma, et al. · Journal of Lipid Research · 98
Rapid de-esterification and loss of eicosapentaenoic acid from rat brain phospholipids: an intracerebroventricular study
2010 · Chuck T. Chen, Zhen Liu, et al. · Journal of Neurochemistry · 97
Dyslipidemia in retinal metabolic disorders
2019 · Zhongjie Fu, Chuck T Chen, et al. · EMBO Molecular Medicine · 92
Brain eicosapentaenoic acid metabolism as a lead for novel therapeutics in major depression
2019 · Richard P. Bazinet, Adam H. Metherel, et al. · Brain Behavior and Immunity · 77
The effect of linoleic acid on the whole body synthesis rates of polyunsaturated fatty acids from α-linolenic acid and linoleic acid in free-living rats
2015 · Anthony F. Domenichiello, Alex P. Kitson, et al. · The Journal of Nutritional Biochemistry · 55
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Genetic Ablation of CD36 Does not Alter Mouse Brain Polyunsaturated Fatty Acid Concentrations
2010 · Byung Jun Song, Adrienne Elbert, et al. · Lipids · 51
Chronic dietary n-6 PUFA deprivation leads to conservation of arachidonic acid and more rapid loss of DHA in rat brain phospholipids
2014 · Lauren E. Lin, Chuck T. Chen, et al. · Journal of Lipid Research · 48
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The very low density lipoprotein receptor is not necessary for maintaining brain polyunsaturated fatty acid concentrations
2010 · Tupur Rahman, Ameer Y. Taha, et al. · Prostaglandins Leukotrienes and Essential Fatty Acids · 43
Omega-3/Omega-6 Long-Chain Fatty Acid Imbalance in Phase I Retinopathy of Prematurity
2022 · Zhongjie Fu, Wenjun Yan, et al. · Nutrients · 32
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Inhibiting Mitochondrial β -Oxidation Selectively Reduces Levels of Nonenzymatic Oxidative Polyunsaturated Fatty Acid Metabolites in the Brain
2013 · Chuck T Chen, Marc-Olivier Trépanier, et al. · Journal of Cerebral Blood Flow & Metabolism · 31
Whole-Body Docosahexaenoic Acid Synthesis-Secretion Rates in Rats Are Constant across a Large Range of Dietary α-Linolenic Acid Intakes
2016 · Anthony F Domenichiello, Alex P Kitson, et al. · Journal of Nutrition · 30
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Oleic acid‐bound FABP7 drives glioma cell proliferation through regulation of nuclear lipid droplet formation
2022 · Banlanjo Abdulaziz Umaru, Yoshiteru Kagawa, et al. · FEBS Journal · 27
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Phospholipid class-specific brain enrichment in response to lysophosphatidylcholine docosahexaenoic acid infusion
2017 · Raphaël Chouinard-Watkins, Chuck T. Chen, et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 25
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Dietary intake of unsaturated fatty acids modulates physiological properties of entorhinal cortex neurons in mice
2012 · Dany Arsenault, Carl Julien, et al. · Journal of Neurochemistry · 25
Intraperitoneal administration of docosahexaenoic acid for 14days increases serum unesterified DHA and seizure latency in the maximal pentylenetetrazol model
2014 · Marc-Olivier Trépanier, Joonbum Lim, et al. · Epilepsy & Behavior · 24
Protein arginine methyltransferase 8 modulates mitochondrial bioenergetics and neuroinflammation after hypoxic stress
2021 · Alexandre Couto E Silva, Celeste Y. Wu, et al. · Journal of Neurochemistry · 23
Works count: 60
Citation count: 2,219
H-index: 24
I10-index: 35
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