Author

Reina Nagase

Observed names: Nagase, Reina, R Nagase, R. Nagase, Reina NAGASE

Observed institutions: Daiichi-Sankyo (Japan), Institute of Medical Science, The University of Tokyo, The University of Tokyo

OpenAlex ID: A5041201931

Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation

2018 · Reina Nagase, Daichi Inoue, et al. · The Journal of Experimental Medicine · 160

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SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS

2014 · D Inoue, J Kitaura, et al. · Leukemia · 92

A novel ASXL1–OGT axis plays roles in H3K4 methylation and tumor suppression in myeloid malignancies

2018 · Daichi Inoue, Takeshi Fujino, et al. · Leukemia · 81

Truncation mutants of ASXL1 observed in myeloid malignancies are expressed at detectable protein levels

2015 · Daichi Inoue, Masaki Matsumoto, et al. · Experimental Hematology · 78

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Biological implications of somatic DDX41 p.R525H mutation in acute myeloid leukemia

2016 · Moe Kadono, Akinori Kanai, et al. · Experimental Hematology · 70

A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1

2023 · Masashi Numata, Noriyasu Haginoya, et al. · Cancer Cell International · 35

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ASXL1 and SETBP1 mutations promote leukaemogenesis by repressing TGFβ pathway genes through histone deacetylation

2018 · Makoto Saika, Daichi Inoue, et al. · Scientific Reports · 34

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The molecular basis of myeloid malignancies

2014 · Toshio KITAMURA, Daichi INOUE, et al. · Proceedings of the Japan Academy Series B · 26

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A C-terminal mutant of CCAAT-enhancer-binding protein α (C/EBPα-Cm) downregulates Csf1r, a potent accelerator in the progression of acute myeloid leukemia with C/EBPα-Cm

2014 · Katsuhiro Togami, Jiro Kitaura, et al. · Experimental Hematology · 11

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High expression of ABCG2 induced by EZH2 disruption has pivotal roles in MDS pathogenesis

2017 · K C Kawabata, Y Hayashi, et al. · Leukemia · 8

Novel working hypothesis for pathogenesis of hematological malignancies: combination of mutations-induced cellular phenotypes determines the disease (cMIP-DD)

2015 · Toshio Kitamura, Naoko Watanabe-Okochi, et al. · The Journal of Biochemistry · 7

SETBP1 Mutations Drive Leukemic Transformation in ASXL1-Mutated MDS

2014 · Daichi Inoue, Hirotaka Matsui, et al. · Blood · 6

[Molecular basis of hematological malignancies].

2014 · Toshio Kitamura, Daichi Inoue, et al. · PubMed · 3

140 the Stability of Epigenetic Factor Asxl1 Is Regulated Through Ubiquitination and Usp7-mediated Deubiquitination

2015 · D. Inoue, R. Nagase, et al. · Leukemia Research · 1

Abstract 1132: Development and characterization of a novel orally bioavailable menin-MLL inhibitor for treatment of acute leukemia patients with MLL-rearrangement or NPM1 mutation

2021 · Masashi Numata, Machiko Shiroishi, et al. · Cancer Research

Mutant ASXL1 activates Akt/mTOR signaling and alters physiological aging of hematopoietic stem cells

2019 · Takeshi Fujino, Susumu Goyama, et al.

Analysis of MDS mice model induced by ASXL1 and RUNX1 mutants

2016 · Reina Nagase, Daichi Inoue, et al. · Experimental Hematology

Novel roles of ASXL1 in epigenetic regulation

2015 · Daichi Inoue, Sayuri Horikawa, et al. · Experimental Hematology

Works count: 21

Citation count: 612

H-index: 9

I10-index: 9