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Brian J. Long

An orally available non-nucleotide STING agonist with antitumor activity
2020 · Bo-Sheng Pan, Samanthi A. Perera, et al. · Science · 674
Discovery of a Novel ERK Inhibitor with Activity in Models of Acquired Resistance to BRAF and MEK Inhibitors
2013 · Erick J. Morris, Sharda Jha, et al. · Cancer Discovery · 673
Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression
2015 · Tikvah K. Hayes, Nicole F. Neel, et al. · Cancer Cell · 264
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Preclinical Evaluation of the WEE1 Inhibitor MK-1775 as Single-Agent Anticancer Therapy
2013 · Amy D. Guertin, Jing Li, et al. · Molecular Cancer Therapeutics · 172
The Farnesyl Transferase Inhibitor (FTI) SCH66336 (lonafarnib) Inhibits Rheb Farnesylation and mTOR Signaling
2005 · Andrea D. Basso, Asra Mirza, et al. · Journal of Biological Chemistry · 162
Signaling pathways of apoptosis activated by aromatase inhibitors and antiestrogens.
2003 · Apinya Thiantanawat, Brian J Long, et al. · PubMed · 161
Aromatase and COX-2 expression in human breast cancers
2001 · A.M.H Brodie, Q Lu, et al. · The Journal of Steroid Biochemistry and Molecular Biology · 150
Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer
2022 · Wonsuk Chang, Michael D. Altman, et al. · Journal of Medicinal Chemistry · 148
Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors
2018 · Stergios J. Moschos, Ryan J. Sullivan, et al. · JCI Insight · 147
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Therapeutic Strategies Using the Aromatase Inhibitor Letrozole and Tamoxifen in a Breast Cancer Model
2004 · B. J. Long, D. Jelovac, et al. · JNCI Journal of the National Cancer Institute · 140
Activation of Mitogen-Activated Protein Kinase in Xenografts and Cells during Prolonged Treatment with Aromatase Inhibitor Letrozole
2005 · Danijela Jelovac, Gauri Sabnis, et al. · Cancer Research · 139
Novel 17-Azolyl Steroids, Potent Inhibitors of Human Cytochrome 17α-Hydroxylase-C17,20-lyase (P45017α): Potential Agents for the Treatment of Prostate Cancer
1998 · Vincent C. O. Njar, Katsuya Kato, et al. · Journal of Medicinal Chemistry · 120
The Role of Growth Factor Receptor Pathways in Human Breast Cancer Cells Adapted to Long-term Estrogen Deprivation
2005 · Gauri J. Sabnis, Danijela Jelovac, et al. · Cancer Research · 106
Intracellular aromatase and its relevance to the pharmacological efficacy of aromatase inhibitors
2001 · A.S Bhatnagar, A.M.H Brodie, et al. · The Journal of Steroid Biochemistry and Molecular Biology · 99
Aromatase and its inhibitors
1999 · Angela Brodie, Qing Lu, et al. · The Journal of Steroid Biochemistry and Molecular Biology · 90
The effect of combining aromatase inhibitors with antiestrogens on tumor growth in a nude mouse model for breast cancer
1999 · Qing Lu, Yang Liu, et al. · Breast Cancer Research and Treatment · 87
Aromatase inhibitors and their antitumor effects in model systems.
1999 · A Brodie, Q Lu, et al. · Endocrine Related Cancer · 75
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The steroidal antiestrogen ICI 182,780 is an inhibitor of cellular aromatase activity
1998 · Brian J. Long, Syreeta L. Tilghman, et al. · The Journal of Steroid Biochemistry and Molecular Biology · 74
The effects of aromatase inhibitors and antiestrogens in the nude mouse model
1998 · Qing Lu, Wei Yue, et al. · Breast Cancer Research and Treatment · 74
Pregnenolone stimulates LNCaP prostate cancer cell growth via the mutated androgen receptor
2000 · Dmitry N. Grigoryev, Brian J. Long, et al. · The Journal of Steroid Biochemistry and Molecular Biology · 72
Antiandrogenic effects of novel androgen synthesis inhibitors on hormone-dependent prostate cancer.
2000 · B J Long, D N Grigoryev, et al. · PubMed · 69
The effect of second-line antiestrogen therapy on breast tumor growth after first-line treatment with the aromatase inhibitor letrozole: long-term studies using the intratumoral aromatase postmenopausal breast cancer model.
2002 · Brian J Long, Danijela Jelovac, et al. · PubMed · 65
Genes for interleukin 7 are transcribed in leukemic cell subsets of individuals with chronic lymphocytic leukemia.
1993 · J Frishman, B Long, et al. · The Journal of Experimental Medicine · 62
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Combination of EP 4 antagonist MF-766 and anti-PD-1 promotes anti-tumor efficacy by modulating both lymphocytes and myeloid cells
2021 · Yun Wang, Long Cui, et al. · OncoImmunology · 56
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Aromatase expression in the human breast
1998 · Angela Brodie, Brian Long, et al. · Breast Cancer Research and Treatment · 54
Works count: 135
Citation count: 4,679
H-index: 33
I10-index: 48
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