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Tahir N. Sheikh

CHIR-124, a Novel Potent Inhibitor of Chk1, Potentiates the Cytotoxicity of Topoisomerase I Poisons In vitro and In vivo
2007 · Archie N. Tse, Katherine G. Rendahl, et al. · Clinical Cancer Research · 147
Chk1 inhibition after replicative stress activates a double strand break response mediated by ATM and DNA-dependent protein kinase
2010 · Samuel McNeely, Chiara Conti, et al. · Cell Cycle · 98
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Drug Synergy Screen and Network Modeling in Dedifferentiated Liposarcoma Identifies CDK4 and IGF1R as Synergistic Drug Targets
2013 · Martin L. Miller, Evan J. Molinelli, et al. · Science Signaling · 86
A Phase 1 Dose-Escalation Study of Irinotecan in Combination with 17-Allylamino-17-Demethoxygeldanamycin in Patients with Solid Tumors
2008 · Archie N. Tse, David S. Klimstra, et al. · Clinical Cancer Research · 59
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90-kDa Heat Shock Protein Inhibition Abrogates the Topoisomerase I Poison-Induced G2/M Checkpoint in p53-Null Tumor Cells by Depleting Chk1 and Wee1
2008 · Archie N. Tse, Tahir N. Sheikh, et al. · Molecular Pharmacology · 44
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Targeted inhibition of glutaminase as a potential new approach for the treatment of NF1 associated soft tissue malignancies
2017 · Tahir N. Sheikh, Parag P. Patwardhan, et al. · Oncotarget · 30
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PTEN regulates sensitivity of melanoma cells to RO4929097, the γ-secretase inhibitor.
2013 · Jayasree S Nair, Tahir Sheikh, et al. · PubMed · 30
Growth Inhibition and Induction of Innate Immune Signaling of Chondrosarcomas with Epigenetic Inhibitors
2021 · Tahir N. Sheikh, Xiao Chen, et al. · Molecular Cancer Therapeutics · 19
A phase 2 study of belinostat and SGI-110 (guadecitabine) for the treatment of unresectable and metastatic conventional chondrosarcoma.
2021 · Jay Oza, Shing Mirn Lee, et al. · Journal of Clinical Oncology · 6
Abstract 5066: Combination treatment with SAHA and 5-Azacytidine (Decitabine) induces apoptosis and suppresses tumor growth in preclinical models of chondrosarcoma
2017 · Tahir Sheikh, Parag Patwardhan, et al. · Cancer Research · 3
ETCTN/NCI 10330: A phase 2 study of belinostat with SGI-110 (guadecitabine) or ASTX727 (decitabine/cedazuridine) for the treatment of unresectable and metastatic conventional chondrosarcoma.
2023 · Kristine Peregrino Lacuna, Shing M Lee, et al. · Journal of Clinical Oncology · 2
Abstract A30: Preclinical study of a combination of mocetinostat (HDAC inhibitor) and 5-AZA-dC (decitabine) in chondrosarcoma
2018 · Tahir N. Sheikh, Parag Patwardhan, et al. · Clinical Cancer Research · 2
Abstract 19: Neurofibromatosis type 1 (NF1) status determines sensitivity of soft tissue sarcoma and melanoma cell lines to glutaminase inhibitors
2016 · Tahir N. Sheikh, Parag P. Patwardhan, et al. · Cancer Research · 2
Abstract 4450: CB839, an orally bioavailable glutaminase inhibitor, shows potent antitumor activity in vitro against models of soft tissue sarcoma and chondrosarcoma
2015 · Tahir N. Sheikh, Parag P. Patwardhan, et al. · Cancer Research · 2
Abstract 6174: ATX-101, a peptide drug targeting PCNA, enhances the effect of gemcitabine in liposarcoma and leiomyosarcoma
2023 · Elgilda Musi, Tahir Sheikh, et al. · Cancer Research · 1
Abstract 248: Targeting compensatory metabolic pathways: Novel approaches to overcome resistance to glutaminase inhibition in NF1 driven malignant peripheral nerve sheath tumors
2020 · Tahir N. Sheikh, Chao Lu, et al. · Cancer Research · 1
Abstract 4977: Development of small molecule inhibitors of protein interaction with glycosaminoglycans
2023 · Tahir N. Sheikh, Elgilda Musi, et al. · Cancer Research
Data from Growth Inhibition and Induction of Innate Immune Signaling of Chondrosarcomas with Epigenetic Inhibitors
2023 · Tahir N. Sheikh, Xiao Chen, et al.
Supplementary Data from Growth Inhibition and Induction of Innate Immune Signaling of Chondrosarcomas with Epigenetic Inhibitors
2023 · Tahir N. Sheikh, Xiao Chen, et al.
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Supplementary Data from Growth Inhibition and Induction of Innate Immune Signaling of Chondrosarcomas with Epigenetic Inhibitors
2023 · Tahir N. Sheikh, Xiao Chen, et al.
Data from Growth Inhibition and Induction of Innate Immune Signaling of Chondrosarcomas with Epigenetic Inhibitors
2023 · Tahir N. Sheikh, Xiao Chen, et al.
Supplementary Data from A Phase 1 Dose-Escalation Study of Irinotecan in Combination with 17-Allylamino-17-Demethoxygeldanamycin in Patients with Solid Tumors
2023 · Archie N. Tse, David S. Klimstra, et al.
Supplementary Material 2 from CHIR-124, a Novel Potent Inhibitor of Chk1, Potentiates the Cytotoxicity of Topoisomerase I Poisons In vitro and In vivo
2023 · Archie N. Tse, Katherine G. Rendahl, et al.
Supplementary Material 3 from CHIR-124, a Novel Potent Inhibitor of Chk1, Potentiates the Cytotoxicity of Topoisomerase I Poisons In vitro and In vivo
2023 · Archie N. Tse, Katherine G. Rendahl, et al.
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Supplementary Material 1 from CHIR-124, a Novel Potent Inhibitor of Chk1, Potentiates the Cytotoxicity of Topoisomerase I Poisons In vitro and In vivo
2023 · Archie N. Tse, Katherine G. Rendahl, et al.
Works count: 43
Citation count: 532
H-index: 8
I10-index: 8
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