Author

Nicholas Joseph Paradis

Observed names: Nicholas J Paradis, Nicholas J. Paradis, Nicholas Paradis, Paradis, Nicholas J.

Institution: Rowan University

Observed institution: Rowan University

ORCID: 0000-0002-4402-7315

Observed ORCID: 0000-0002-4402-7315

OpenAlex ID: A5041361277

Mechanistic insight on the remdesivir binding to RNA-Dependent RNA polymerase (RdRp) of SARS-cov-2

2020 · Muhammad Arba, Setyanto Tri Wahyudi, et al. · Computers in Biology and Medicine · 46

Effects of Ionic Liquids on Metalloproteins

2021 · Aashka Y. Patel, Keertana S. Jonnalagadda, et al. · Molecules · 21

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Novel Inhibitors to MmpL3 Transporter of Mycobacterium tuberculosis by Structure-Based High-Throughput Virtual Screening and Molecular Dynamics Simulations

2024 · Hetanshi Choksi, Justin Carbone, et al. · ACS Omega · 16

Inhibition Mechanism of Anti-TB Drug SQ109: Allosteric Inhibition of TMM Translocation of Mycobacterium Tuberculosis MmpL3 Transporter

2023 · Justin Carbone, Nicholas J. Paradis, et al. · Journal of Chemical Information and Modeling · 14

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To probe the binding of TMPyP4 to c-MYC G-quadruplex with in water and in imidazolium-based ionic liquids using spectroscopy coupled with molecular dynamics simulations

2022 · Nicholas J. Paradis, Austin Clark, et al. · Journal of Molecular Liquids · 13

Thermodynamic destabilization of azurin by four different tetramethylguanidinium amino acid ionic liquids

2021 · Isabella DeStefano, Gabriella DeStefano, et al. · International Journal of Biological Macromolecules · 13

New acridone derivatives to target telomerase and oncogenes – an anticancer approach

2025 · Tiago J. S. Marques, Diana Salvador, et al. · RSC Medicinal Chemistry · 8

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Binding Mechanism of the Active Form of Molnupiravir to RdRp of SARS-CoV-2 and Designing Potential Analogues: Insights from Molecular Dynamics Simulations

2024 · Justin Carbone, Nicholas J. Paradis, et al. · ACS Omega · 8

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Unraveling the binding mechanism of the active form of Remdesivir to RdRp of SARS-CoV-2 and designing new potential analogues: Insights from molecular dynamics simulations

2022 · Muhammad Arba, Nicholas Paradis, et al. · Chemical Physics Letters · 8

Phenolic compounds as potential adenosine deaminase inhibitors: molecular docking and dynamics simulation coupled with MM-GBSA calculations

2023 · Abdullahi Ibrahim Uba, Nicholas Joseph Paradis, et al. · Amino Acids · 7

Effects of Ionic Liquids on Laccase from Trametes versicolor

2021 · Aashka Y. Patel, Austin K. Clark, et al. · Biophysica · 7

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L-shape distribution of the relative substitution rate (c/μ) observed for SARS-COV-2’s genome, inconsistent with the selectionist theory, the neutral theory and the nearly neutral theory but a near-neutral balanced selection theory: implication on “neutralist-selectionist” debate

2023 · Chun Wu, Nicholas J. Paradis, et al. · Computers in Biology and Medicine · 6

To probe the binding pathway of a selective compound (D089-0563) to c-MYC Pu24 G-quadruplex using free ligand binding simulations and Markov state model analysis

2020 · Brian Chen, Griffin Fountain, et al. · Physical Chemistry Chemical Physics · 6

Oncogenic and telomeric G-quadruplexes: Targets for porphyrin-triphenylphosphonium conjugates

2024 · Nuno M.M. Moura, Sofia Guedes, et al. · International Journal of Biological Macromolecules · 5

Probing the Activation Mechanisms of Agonist DPI-287 to Delta-Opioid Receptor and Novel Agonists Using Ensemble-Based Virtual Screening with Molecular Dynamics Simulations

2023 · Emily Dean, AnneMarie Dominique, et al. · ACS Omega · 4

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Computational analysis of natural compounds as potential phosphodiesterase type 5A inhibitors

2024 · Abdullahi Ibrahim Uba, Nicholas Joseph Paradis, et al. · Computational Biology and Chemistry · 3

Enhanced detection and molecular modeling of adaptive mutations in SARS-CoV-2 coding and non-coding regions using the c/µ test

2024 · Nicholas J Paradis, Chun Wu · Virus Evolution · 3

Substitution-Mutation Rate Ratio (c/µ) As Molecular Adaptation Test Beyond Ka/Ks: A SARS-COV-2 Case Study

2025 · Chun Wu, Nicholas J. Paradis, et al. · Journal of Molecular Evolution · 2

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Elucidating the stabilization mechanism of a K+-depleted c-MYC DNA G-quadruplex in hydrophobic imidazolium-based ionic liquids using spectroscopy coupled with molecular dynamics simulations

2024 · Nicholas J. Paradis, Austin Clark, et al. · Journal of Molecular Liquids · 1

Appraisals on the chemical characterization and biological potentials of Ranunculus constantinopolitanus extracts using chromatographic, computational, and molecular network approaches

2023 · Irina Lazarova, Gokhan Zengin, et al. · Food and Chemical Toxicology · 1

Zika Virus Molecular Evolution Explained by Near Neutral Balanced Selectionist Theory

2026 · Paradis, Nicholas J., Wu, Chun · Rowan Digitals Works (Rowan University)

Near Neutral Selectionist Theories (NNST) for SARS-CoV-2 suggested by the substitution-mutation ratio (c/µ) analysis

2026 · Chun Wu, Nicholas J. Paradis · PLoS ONE

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Elucidating HER2-directed chimeric antigen receptor (CAR) activation mechanism using homology modeling and all-atom molecular dynamics simulation

2026 · Mariya Hryb, Leah Davis, et al. · Computational and Structural Biotechnology Journal

L-Shaped Distributions of the Relative Substitution Rates (c/micro) in SARS-COV-2 with or without Molecular Clocks, Challenging Mainstream Evolutionary Theories

2024 · Chun Wu, Nicholas J. Paradis · bioRxiv (Cold Spring Harbor Laboratory)

Surfactant ionic liquids alter the stabilities of G-quadruplex DNA and RNA structures

2024 · Achismita Dutta, Austin K. Clark, et al. · Biophysical Journal

Works count: 27

Citation count: 192

H-index: 8

I10-index: 6