Author

Charly Ryan Good

Observed names: Charly R Good, Charly R. Good, Good, Charly R.

Institutions: University of Pennsylvania Health System, University of Pennsylvania

Observed institutions: University of Pennsylvania Health System, University of Pennsylvania, Temple University

ORCID: 0000-0002-9934-9696

Observed ORCID: 0000-0002-9934-9696

OpenAlex ID: A5043619159

An NK-like CAR T cell transition in CAR T cell dysfunction

2021 · Charly R. Good, M. Angela Aznar, et al. · Cell · 396

Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction

2020 · Nathan Singh, Yong Gu Lee, et al. · Cancer Discovery · 294

Deletion of the inhibitory co-receptor CTLA-4 enhances and invigorates chimeric antigen receptor T cells

2023 · Sangya Agarwal, M. Angela Aznar, et al. · Immunity · 185

TET1-Mediated Hypomethylation Activates Oncogenic Signaling in Triple-Negative Breast Cancer

2018 · Charly Ryan Good, Shoghag Panjarian, et al. · Cancer Research · 157

p53 mediates target gene association with nuclear speckles for amplified RNA expression

2021 · Katherine A. Alexander, Allison Coté, et al. · Molecular Cell · 111

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A novel isoform of TET1 that lacks a CXXC domain is overexpressed in cancer

2017 · Charly R. Good, Jozef Madzo, et al. · Nucleic Acids Research · 73

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Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer

2022 · Mihir Rajurkar, Aparna R. Parikh, et al. · Cancer Discovery · 61

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Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer.

2022 · Mihir Rajurkar, Aparna R Parikh, et al. · PubMed · 31

TOX2 coordinates with TET2 to positively regulate central memory differentiation in human CAR T cells

2023 · Sierra M. Collins, Katherine A. Alexander, et al. · Science Advances · 30

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Clinical and molecular dissection of CAR T cell resistance in pancreatic cancer

2025 · M. Angela Aznar, Charly R. Good, et al. · Cell Reports Medicine · 24

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Histone acetylation in an Alzheimer’s disease cell model promotes homeostatic amyloid-reducing pathways

2024 · Daniel C. Xu, Hanna Sas-Nowosielska, et al. · Acta Neuropathologica Communications · 22

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Deciphering the role of histone modifications in memory and exhausted CD8 T cells

2025 · Hua Huang, Amy E. Baxter, et al. · Scientific Reports · 15

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Comparison of genotoxic versus nongenotoxic stabilization of p53 provides insight into parallel stress-responsive transcriptional networks

2019 · Allison N. Catizone, Charly Ryan Good, et al. · Cell Cycle · 11

Demethylator phenotypes in acute myeloid leukemia

2018 · Andrew D. Kelly, Jozef Madzo, et al. · Leukemia · 11

Chromatin repression by PRC2 results in reduced gene expression driving key features of CD8 T cell exhaustion

2025 · Parisa Samareh, Paula Agudelo-Garcia, et al. · The Journal of Immunology · 1

237 Enhancing mesothelin-directed CAR T cell therapy for unresectable or metastatic pancreatic adenocarcinoma

2024 · M Angela Aznar Gomez, Charly R Good, et al. · Regular and Young Investigator Award Abstracts · 1

Abstract 60: Induction of T cell dysfunction and NK-like T cell differentiation in vitro and in patients after CAR T cell treatment

2021 · Charly R. Good, Shunichiro Kuramitsu, et al. · Cancer Research · 1

Impaired tumor death receptor signaling drives resistance to CAR T cell therapy

2019 · Nathan Singh, Olga Shestova, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1

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Abstract 2659: A novel isoform of TET1 that lacks a CXXC domain is overexpressed in cancer

2016 · Charly R. Good, Jozef Madzo, et al. · Cancer Research · 1

Histone acetylation in an Alzheimer’s disease cell model promotes homeostatic amyloid-reducing pathways

2023 · Daniel C. Xu, Hanna Sas-Nowosielska, et al. · bioRxiv (Cold Spring Harbor Laboratory)

Data from Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer