Author

Giorgio Gaudiano

Observed names: G Gaudiano, G. GAUDIANO, G. Gaudiano, GIORGIO GAUDIANO, Giorgio. Gaudiano

Observed institutions: University of Delhi, National Institutes of Health, University of Colorado Boulder, University of L'Aquila, United States Air Force, National Research Council, United States Air Force Academy, Politecnico di Milano

OpenAlex ID: A5043655879

Redox Pathway Leading to the Alkylation of DNA by the Anthracycline, Antitumor Drugs Adriamycin and Daunomycin

1997 · Dylan J. Taatjes, Giorgio Gaudiano, et al. · Journal of Medicinal Chemistry · 128

Alkylation of DNA by the Anthracycline, Antitumor Drugs Adriamycin and Daunomycin

1996 · Dylan J. Taatjes, Giorgio Gaudiano, et al. · Journal of Medicinal Chemistry · 85

Production of Formaldehyde and DNA−Adriamycin or DNA−Daunomycin Adducts, Initiated through Redox Chemistry of Dithiothreitol/Iron, Xanthine Oxidase/NADH/Iron, or Glutathione/Iron

1997 · Dylan J. Taatjes, Giorgio Gaudiano, et al. · Chemical Research in Toxicology · 53

Palladium(II) complexes with sulphonium ylides

1974 · Pierfrancesco Bravo, Giovanni Fronza, et al. · Journal of Organometallic Chemistry · 47

Redox chemistry of anthracycline antitumor drugs and use of captodative radicals as tools for its elucidation and control

1991 · Giorgio Gaudiano, Tad H. Koch · Chemical Research in Toxicology · 46

Lack of glutathione conjugation to adriamycin in human breast cancer MCF-7/DOX cells

2000 · Giorgio Gaudiano, Tad H Koch, et al. · Biochemical Pharmacology · 45

Intramolecular trapping of the quinone methide from reductive cleavage of daunomycin with oxygen and nitrogen nucleophiles

1990 · Giorgio Gaudiano, Massimo Frigerio, et al. · Journal of the American Chemical Society · 37

Alkylation of enamines by α-haloketoximes

1970 · P. Bravo, G. Gaudiano, et al. · Tetrahedron · 32

The Biosynthesis of the Macrolide Antibiotic Lucensomycin

1969 · D. G. MANWARING, R. W. RICKARDS, et al. · The Journal of Antibiotics · 27

PDF

The reaction of dimethylsulphonium methylide with aromatic ortho-aminocarbonyl compounds: a new synthesis of indoles

1969 · P. Bravo, G. Gaudiano, et al. · Tetrahedron Letters · 26

Doxorubicin-induced skin necrosis in the swine model: protection with a novel radical dimer.

1986 · S D Averbuch, G Gaudiano, et al. · Journal of Clinical Oncology · 21

Spectroscopic and kinetic evidence for the tautomer of 7-deoxyaklavinone as an intermediate in the reductive coupling of aclacinomycin A

1984 · Don L. Kleyer, Giorgio Gaudiano, et al. · Journal of the American Chemical Society · 21

Dimethyloxosulphonium methylide: A tool for the synthesis of five-membered heterocycles

1967 · G. Gaudiano, A. Umani-Ronchi, et al. · Tetrahedron Letters · 21

Induction of apoptosis in neoplastic cells by anthracycline antitumor drugs: nuclear and cytoplasmic triggering?

1999 · A Serafino, P Sinibaldi-Vallebona, et al. · PubMed · 20

Reaction of Anthracycline Antitumor Drugs with Reduced Glutathione. Formation of Aglycon Conjugates

1994 · Giorgio Gaudiano, Katheryn Resing, et al. · Journal of the American Chemical Society · 20

The reaction of keto-stabilized sulphonium and arsonium ylides with α-chlorooximes

1972 · P. Bravo, G. Gaudiano, et al. · Tetrahedron · 20

Experimental chemotherapy-induced skin necrosis in swine. Mechanistic studies of anthracycline antibiotic toxicity and protection with a radical dimer compound.

1988 · S D Averbuch, M Boldt, et al. · Journal of Clinical Investigation · 19

PDF

Base-induced cyclization of 2-oximinophosphonium salts. Synthesis and spectroscopic properties of 1,2,5-oxazaphosph(V)ol-2-ines

1968 · Giorgio Gaudiano, Rosanna Mondelli, et al. · The Journal of Organic Chemistry · 19

Synthesis of a capto-dative diradical and its reversible oligomerization to macrocycles of coronand structure

1984 · Giorgio Gaudiano, Karenkay Sweeney, et al. · Journal of the American Chemical Society · 18

The reaction between dimethyloxosulphonium methylide and benzonitrile oxide

1966 · A. Umani-Ronchi, P. Bravo, et al. · Tetrahedron Letters · 16

Leucodaunomycins, new intermediates in the redox chemistry of daunomycin

1991 · Donald M. Bird, Giorgio Gaudiano, et al. · Journal of the American Chemical Society · 15

Reaction of the quinonemethide from reductive glycosidic cleavage of daunomycin with molecular oxygen. Evidence for semiquinonemethide formation

1990 · Giorgio Gaudiano, Tad H. Koch · Journal of the American Chemical Society · 15

Synthesis and reactivity of captodative diradical oligomers incorporating the 3,5,5-trimethyl-2-oxomorpholin-3-yl (TM-3) unit

1988 · Olester Benson, Giorgio Gaudiano, et al. · The Journal of Organic Chemistry · 15

Formation and autocatalytic destruction of the quinone methide from reductive cleavage of Menogaril

1988 · Marybeth. Boldt, Giorgio. Gaudiano, et al. · Journal of the American Chemical Society · 15

Substituent effects on the redox chemistry of anthracycline antitumor drugs

1987 · Marybeth Boldt, Giorgio Gaudiano, et al. · The Journal of Organic Chemistry · 15

Works count: 76

Citation count: 971

H-index: 18

I10-index: 32