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Greg R. Harlow

Analysis of human cytochrome P450 3A4 cooperativity: Construction and characterization of a site-directed mutant that displays hyperbolic steroid hydroxylation kinetics
1998 · Greg R. Harlow, James R. Halpert · Proceedings of the National Academy of Sciences · 228
Identification of High Affinity Binding Sites for LexA which Define New DNA Damage-inducible Genes in Escherichia coli
1994 · L.Kevin Lewis, Greg R. Harlow, et al. · Journal of Molecular Biology · 206
Alanine-scanning Mutagenesis of a Putative Substrate Recognition Site in Human Cytochrome P450 3A4
1997 · Greg R. Harlow, James R. Halpert · Journal of Biological Chemistry · 146
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Structure−Function Relationships of Human Liver Cytochromes P450 3A: Aflatoxin B1 Metabolism as a Probe
1998 · Huifen Wang, Ryan Dick, et al. · Biochemistry · 120
Analysis of Four Residues within Substrate Recognition Site 4 of Human Cytochrome P450 3A4: Role in Steroid Hydroxylase Activity and α-Naphthoflavone Stimulation
1998 · Tammy L. Domanski, Juping Liu, et al. · Archives of Biochemistry and Biophysics · 115
Dual Role of Human Cytochrome P450 3A4 Residue Phe-304 in Substrate Specificity and Cooperativity
2000 · Tammy L. Domanski, You-Ai He, et al. · Journal of Pharmacology and Experimental Therapeutics · 108
Isolation of uvh1, an Arabidopsis mutant hypersensitive to ultraviolet light and ionizing radiation.
1994 · G R Harlow, M E Jenkins, et al. · The Plant Cell · 95
Arabidopsis mutants deficient in T-DNA integration.
1995 · R V Sonti, M Chiurazzi, et al. · Proceedings of the National Academy of Sciences · 90
Isolation, Heterologous Expression and Functional Characterization of a Novel Cytochrome P450 3A Enzyme from a Canine Liver cDNA Library
1997 · David J. Fraser, René Feyereisen, et al. · Journal of Pharmacology and Experimental Therapeutics · 62
2,2‘,3,3‘,6,6‘-Hexachlorobiphenyl Hydroxylation by Active Site Mutants of Cytochrome P450 2B1 and 2B11
1999 · Stephen C. Waller, You Ai He, et al. · Chemical Research in Toxicology · 61
Radiation-sensitive mutants of Arabidopsis thaliana.
1995 · M E Jenkins, G R Harlow, et al. · Genetics · 57
Site-directed mutagenesis of putative substrate recognition sites in cytochrome P450 2B11: importance of amino acid residues 114, 290, and 363 for substrate specificity.
1994 · J A Hasler, G R Harlow, et al. · Molecular Pharmacology · 49
Mutagenesis Study of Asp-290 in Cytochrome P450 2B11 Using a Fusion Protein with Rat NADPH-Cytochrome P450 Reductase
1996 · Greg R. Harlow, James R. Halpert · Archives of Biochemistry and Biophysics · 31
Functional interaction between amino-acid residues 242 and 290 in cytochromes P-450 2B1 and 2B11
1997 · Greg R Harlow, You Ai He, et al. · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · 28
Discovery of the first non-ATP competitive IGF-1R kinase inhibitors: Advantages in comparison with competitive inhibitors
2011 · Dominique Lesuisse, Jacques Mauger, et al. · Bioorganic & Medicinal Chemistry Letters · 23
Use of the Steroid Derivative RPR 106541 in Combination with Site-Directed Mutagenesis for Enhanced Cytochrome P-450 3A4 Structure/Function Analysis
1999 · Jeffrey C. Stevens, Tammy L. Domanski, et al. · Journal of Pharmacology and Experimental Therapeutics · 18
Structural Determinants of Progesterone Hydroxylation by Cytochrome P450 2B5: The Role of Nonsubstrate Recognition Site Residues
1998 · You Qun He, Greg R. Harlow, et al. · Archives of Biochemistry and Biophysics · 18
Use of Chimeric Enzymes and Site-Directed Mutagenesis for Identification of Three Key Residues Responsible for Differences in Steroid Hydroxylation between Canine Cytochromes P-450 3A12 and 3A26
1999 · David J Fraser, You Qun He, et al. · Molecular Pharmacology · 13
Escherichia coli expression and substrate specificities of canine cytochrome P450 3A12 and rabbit cytochrome P450 3A6.
1996 · S L Born, D J Fraser, et al. · Journal of Pharmacology and Experimental Therapeutics · 12
Characterization of the progesterone 21-hydroxylase activity of canine cytochrome P450 PBD-2/P450 2B11 through reconstitution, heterologous expression, and site-directed mutagenesis.
1995 · S L Born, G H John, et al. · Drug Metabolism and Disposition · 12
Isolation of uvh1, an Arabidopsis Mutant Hypersensitive to Ultraviolet Light and Ionizing Radiation
1994 · Greg R. Harlow, Michael E. Jenkins, et al. · The Plant Cell · 4
On-Bead and Solution Screening Approaches for Genomically Derived Targets: Discovery of Surrogate Ligands and Substrates Using Combinatorial Chemistry Libraries
2003 · David S. Thorpe, Gérard Rossé, et al. · Humana Press eBooks · 2
Isolation and characterization of ultraviolet light hypersensitive mutants of Arabidopsis thaliana.
1993 · Greg R. Harlow · UA Campus Repository (The University of Arizona)
Works count: 27
Citation count: 1,498
H-index: 17
I10-index: 20
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