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R. Baurain

A covalent linkage between daunorubicin and proteins that is stable in serum and reversible by lysosomal hydrolases, as required for a lysosomotropic drug-carrier conjugate: in vitro and in vivo studies.
1982 · A Trouet, M Masquelier, et al. · Proceedings of the National Academy of Sciences · 234
Amino acid and dipeptide derivatives of daunorubicin. 1. Synthesis, physicochemical properties, and lysosomal digestion
1980 · Michele Masquelier, Roger Baurain, et al. · Journal of Medicinal Chemistry · 69
Extracellularly tumor-activated prodrugs for the selective chemotherapy of cancer: application to doxorubicin and preliminary in vitro and in vivo studies.
2001 · A Trouet, A Passioukov, et al. · PubMed · 68
Amino acid and dipeptide derivatives of daunorubicin. 2. Cellular pharmacology and antitumor activity of L1210 leukemic cells in vitro and in vivo
1980 · R. Baurain, M. Masquelier, et al. · Journal of Medicinal Chemistry · 53
Rapid determination of doxorubicin and its fluorescent metabolites by high pressure liquid chromatography
1979 · R. Baurain, D.Deprez-De Campeneere, et al. · Analytical Biochemistry · 47
Cellular uptake and metabolism of daunorubicin as determined by high-performance liquid chromatogaphy
1978 · Roger Baurain, Andrée Zenebergh, et al. · Journal of Chromatography A · 47
DNA-binding parameters of daunorubicin and doxorubicin in the conditions used for studying the interaction of anthracycline-DNA complexes with cells in vitro
1979 · Y.-J. Schneider, R. Baurain, et al. · Cancer Chemotherapy and Pharmacology · 44
Development of new derivatives of primaquine by association with lysosomotropic carriers.
1981 · A U Trouet, P Pirson, et al. · Europe PMC (PubMed Central) · 43
Determination of daunorubicin and its main metabolites in plasma, urine and leukaemic cells in patients with acute myeloblastic leukaemia
1980 · Christer Paul, Roger Baurain, et al. · Cancer Letters · 43
Determination of daunorubicin, doxorubicin and their fluorescent metabolites by high-pressure liquid chromatography: Plasma levels in DBA2 mice
1979 · R. Baurain, D. Deprez-De Campeneere, et al. · Cancer Chemotherapy and Pharmacology · 41
Comparative study in mice of the toxicity, pharmacology, and therapeutic activity of daunorubicin-DNA and doxorubicin-DNA complexes
1979 · D. Deprez-De Campeneere, R. Baurain, et al. · Cancer Chemotherapy and Pharmacology · 29
Photolysis of Desmosine and Isodesmosine by Ultraviolet Light
1976 · Roger BAURAIN, Jean‐François LAROCHELLE, et al. · European Journal of Biochemistry · 29
Drug Targeting in Human Cancer Chemotherapy
1984 · Y.-J. Schneider, J. Abarca, et al. · Springer eBooks · 28
High dose melphalan in children with advanced malignant disease: A pharmacokinetic study
1985 · J. Ninane, R. Baurain, et al. · Cancer Chemotherapy and Pharmacology · 25
The mechanism for cellular uptake, storage and release of daunorubicin
1980 · Curt Peterson, Roger Baurain, et al. · Biochemical Pharmacology · 24
Alkylating activity in serum, urine, and CSF following high-dose ifosfamide in children
1989 · Jacques Ninane, Roger Baurain, et al. · Cancer Chemotherapy and Pharmacology · 23
Accumulation and metabolism of new anthracycline derivatives in the heart after IV injection into mice
1982 · D. Deprez-de Campeneere, R. Baurain, et al. · Cancer Chemotherapy and Pharmacology · 23
Effect of MRC-5 fibroblast conditioned medium on breast cancer cell motility and invasion in vitro
1998 · N. Heylen, R. Baurain, et al. · Clinical & Experimental Metastasis · 22
Degradation of doxorubicin and daunorubicin in human and rabbit biological fluids
1986 · Dominique M. Maniez-Devos, Roger Baurain, et al. · Journal of Pharmaceutical and Biomedical Analysis · 20
Cellular pharmacokinetics of aclacinomycin A in cultured L1210 cells: Comparison with daunorubicin and doxorubicin
1982 · A. Zenebergh, R. Baurain, et al. · Cancer Chemotherapy and Pharmacology · 20
Human pharmacokinetics of N-L-leucyl-doxorubicin, a new anthracycline derivative, and its correlation with clinical toxicities
1992 · Pierre Canal, Jacques Robert, et al. · Clinical Pharmacology & Therapeutics · 18
Liposomes as Lysosomotropic Carriers
1978 · Christian de Duve, André Trouet, et al. · Annals of the New York Academy of Sciences · 18
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Current antimalarials and new drug developments
1984 · W Peters, W. H. G. Richards, et al. · Springer eBooks · 17
Targeting of Antitumour and Antiprotozoal Drugs by Covalent Linkage to Protein Carriers
1982 · André Trouet, Roger Baurain, et al. · Springer eBooks · 17
High-performance liquid chromatographic determination of vinblastine, 4-O-deacetylvinblastine and the potential metabolise 4-O-deacetylvinblastine-3-oic acid in biological fluids
1991 · O. van Tellingen, J.H. Beijnen, et al. · Journal of Chromatography A · 16
Works count: 60
Citation count: 1,185
H-index: 20
I10-index: 33
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