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Jürgen Thomale

Targeted Single-Wall Carbon Nanotube-Mediated Pt(IV) Prodrug Delivery Using Folate as a Homing Device
2008 · Shanta Dhar, Zhuang Liu, et al. · Journal of the American Chemical Society · 697
ERCC1 Isoform Expression and DNA Repair in Non–Small-Cell Lung Cancer
2013 · Luc Friboulet, Ken André Olaussen, et al. · New England Journal of Medicine · 373
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Cisplatin sensitivity of testis tumour cells is due to deficiency in interstrand-crosslink repair and low ERCC1-XPF expression
2010 · Svetlana Usanova, Andrea Piée-Staffa, et al. · Molecular Cancer · 166
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06‐Methyldeoxyguanosine in oesophageal dna among individuals at high risk of oesophageal cancer
1985 · D. Umbenhauer, C. P. Wild, et al. · International Journal of Cancer · 161
Alternative pathways for the in vivo repair of O6‐alkylguanine and O4‐alkylthymine in Escherichia coli: the adaptive response and nucleotide excision repair.
1988 · L. Samson, J. Thomale, et al. · The EMBO Journal · 136
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Overexpression of cMOAT (MRP2/ABCC2) Is Associated with Decreased Formation of Platinum-DNA Adducts and Decreased G2-Arrest in Melanoma Cells Resistant to Cisplatin
2003 · Bernd Liedert, Verena Materna, et al. · Journal of Investigative Dermatology · 129
DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression
2016 · Stephanie Hampp, Tina Kiessling, et al. · Proceedings of the National Academy of Sciences · 98
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p53 Hypersensitivity Is the Predominant Mechanism of the Unique Responsiveness of Testicular Germ Cell Tumor (TGCT) Cells to Cisplatin
2011 · Matthias Gutekunst, Moshe Oren, et al. · PLoS ONE · 97
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Differential effect of quercetin on cisplatin-induced toxicity in kidney and tumor tissues
2017 · Penélope D. Sánchez-González, Francisco J. López-Hernández, et al. · Food and Chemical Toxicology · 89
Gene expression signatures separate B-cell chronic lymphocytic leukaemia prognostic subgroups defined by ZAP-70 and CD38 expression status
2006 · A Hüttmann, L Klein-Hitpass, et al. · Leukemia · 82
Protection of platinum–DNA adduct formation and reversal of cisplatin resistance by anti‐MRP2 hammerhead ribozymes in human cancer cells
2005 · Verena Materna, Bernd Liedert, et al. · International Journal of Cancer · 82
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1,N6-etheno-2′ -deoxyadenosine and 3,N4-etheno-2′-deoxycytidine detected by monoclonal antibodies in lung and liver DNA of rats exposed to vinyl chloride
1989 · Gertrud Eberle, Alain Barbin, et al. · Carcinogenesis · 80
FTO levels affect RNA modification and the transcriptome
2012 · Tea Berulava, Matthias Ziehe, et al. · European Journal of Human Genetics · 73
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DNA excision repair profiles of normal and leukemic human lymphocytes: functional analysis at the single-cell level.
1997 · C Buschfort, M R Muller, et al. · PubMed · 71
Metformin enhances the radiosensitizing effect of cisplatin in non-small cell lung cancer cell lines with different cisplatin sensitivities
2019 · Muhammad Assad Riaz, Ali Sak, et al. · Scientific Reports · 62
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Differential contributory roles of nucleotide excision and homologous recombination repair for enhancing cisplatin sensitivity in human ovarian cancer cells
2011 · Qi-En Wang, Keisha Milum, et al. · Molecular Cancer · 62
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Combined PER2 and CRY1 expression predicts outcome in chronic lymphocytic leukemia
2009 · Lewin Eisele, Robert Prinz, et al. · European Journal Of Haematology · 62
Cisplatin-induced neuropathic pain is mediated by upregulation of N-type voltage-gated calcium channels in dorsal root ganglion neurons
2016 · Markus Leo, Linda-Isabell Schmitt, et al. · Experimental Neurology · 52
Down-regulation of DNA repair in human CD34+progenitor cells corresponds to increased drug sensitivity and apoptotic response
2002 · Claudia Buschfort-Papewalis, Thomas Moritz, et al. · Blood · 52
Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation
2014 · Ulrike Keitel, Andreas Scheel, et al. · Oncotarget · 46
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PARP1 impact on DNA repair of platinum adducts: Preclinical and clinical read-outs
2013 · Ken A. Olaussen, Julien Adam, et al. · Lung Cancer · 46
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Fast repair of O 6 -ethylguanine, but not O 6 -methylguanine, in transcribed genes prevents mutation of H- ras in rat mammary tumorigenesis induced by ethylnitrosourea in place of methylnitrosourea
1998 · Jörg Engelbergs, Jürgen Thomale, et al. · Proceedings of the National Academy of Sciences · 45
Repair of O6-ethylguanine in DNA protects rat 208F cells from tumorigenic conversion by N-ethyl-N-nitrosourea.
1990 · J Thomale, N H Huh, et al. · Proceedings of the National Academy of Sciences · 45
Multifaceted Mechanisms of Cisplatin Resistance in Long-Term Treated Urothelial Carcinoma Cell Lines
2018 · Margaretha A. Skowron, Margarita Melnikova, et al. · International Journal of Molecular Sciences · 43
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Differential formation and repair of the mutagenic DNA alkylation product O6-ethylguanine in transcribed and nontranscribed genes of the rat.
1994 · J. Thomale, K. Hochleitner, et al. · Journal of Biological Chemistry · 42
Works count: 121
Citation count: 3,961
H-index: 32
I10-index: 68
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