Author

Elian Dupré

Observed names: Dupre, Elian, Dupré Elian, Dupré, Elian, E. Dupre, Elian Dupre

Institutions: Centre National de la Recherche Scientifique, Inserm, Université de Lille, Institut Pasteur de Lille, Centre Hospitalier Universitaire de Lille, Approches épidémiologiques et moléculaires intégratives visant à améliorer la compréhension des maladies chroniques liées au vieillissement, Integrative Structural Biology

Observed institutions: Centre National de la Recherche Scientifique, Inserm, Université de Lille, Institut Pasteur de Lille, Centre Hospitalier Universitaire de Lille, Center for Infection and Immunity of Lille, Unité de Glycobiologie Structurale et Fonctionnelle, Approches épidémiologiques et moléculaires intégratives visant à améliorer la compréhension des maladies chroniques liées au vieillissement, Lille Neurosciences & Cognition, Integrative Structural Biology, LabEx DISTALZ, Université Lille Nord de France

ORCID: 0000-0001-5281-0337

Observed ORCID: 0000-0001-5281-0337

OpenAlex ID: A5047160661

Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment

2022 · Clément Danis, Elian Dupré, et al. · Molecular Therapy · 78

Aggregate-selective removal of pathological tau by clustering-activated degraders

2024 · Jonathan Benn, Shi Cheng, et al. · Science · 75

Periplasmic domain of the sensor-kinase BvgS reveals a new paradigm for the Venus flytrap mechanism

2010 · Julien Herrou, Coralie Bompard, et al. · Proceedings of the National Academy of Sciences · 51

Translocation path of a substrate protein through its Omp85 transporter

2014 · Catherine Baud, Jérémy Guérin, et al. · Nature Communications · 50

Virulence Regulation with Venus Flytrap Domains: Structure and Function of the Periplasmic Moiety of the Sensor-Kinase BvgS

2015 · Elian Dupré, Julien Herrou, et al. · PLoS Pathogens · 41

Single Domain Antibody Fragments as New Tools for the Detection of Neuronal Tau Protein in Cells and in Mice Studies

2019 · Elian Dupré, Clément Danis, et al. · ACS Chemical Neuroscience · 35

Balance between Coiled-Coil Stability and Dynamics Regulates Activity of BvgS Sensor Kinase in Bordetella

2016 · E. Lesne, E.-M. Krammer, et al. · mBio · 23

Characterization of the PAS domain in the sensor-kinase BvgS: mechanical role in signal transmission

2013 · Elian Dupré, Alexandre Wohlkonig, et al. · BMC Microbiology · 23

Signal Transduction by BvgS Sensor Kinase

2015 · Elian Dupré, Elodie Lesne, et al. · Journal of Biological Chemistry · 21

Novel dithiocarbamates selectively inhibit 3CL protease of SARS-CoV-2 and other coronaviruses

2023 · Lucile Brier, Haitham Hassan, et al. · European Journal of Medicinal Chemistry · 20

Coiled-Coil Antagonism Regulates Activity of Venus Flytrap-Domain-Containing Sensor Kinases of the BvgS Family

2018 · Elodie Lesne, Elian Dupré, et al. · mBio · 19

Inhibition of tau neuronal internalization using anti-tau single domain antibodies

2025 · Clément Danis, Elian Dupré, et al. · Nature Communications · 18

Magnetic resonance investigation of conformational responses of tau protein to specific phosphorylation

2023 · Alessia Lasorsa, Hamida Merzougui, et al. · Biophysical Chemistry · 15

Conformational Changes of an Interdomain Linker Mediate Mechanical Signal Transmission in Sensor Kinase BvgS

2017 · Elodie Lesne, Elian Dupré, et al. · Journal of Bacteriology · 14

Tanycytic degeneration impairs tau clearance and contributes to Alzheimer’s disease pathology

2026 · Florent Sauvé, Ricardo Martinez-Gómez, et al. · Cell Press Blue · 12

Deciphering the Structure and Formation of Amyloids in Neurodegenerative Diseases With Chemical Biology Tools

2022 · Isabelle Landrieu, Elian Dupré, et al. · Frontiers in Chemistry · 12

Nuclear Magnetic Resonance Spectroscopy Insights into Tau Structure in Solution: Impact of Post-translational Modifications

2019 · Clément Danis, Elian Dupré, et al. · Advances in experimental medicine and biology · 11

A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein

2024 · Justine Mortelecque, Orgeta Zejneli, et al. · Journal of Biological Chemistry · 10

Structural Insight into the Role of the PAS Domain for Signal Transduction in Sensor Kinase BvgS

2021 · Elian Dupré, Bernard Clantin, et al. · Journal of Bacteriology · 10

BvgS of Pathogenic Bordetellae: a Paradigm for Sensor-kinases with Venus Flytrap Perception Domains

2012 · Françoise Jacob‐Dubuisson, René Wintjens, et al. · Dépôt institutionnel de l'Université libre de Bruxelles (Université Libre de Bruxelles) · 10

Conformation and Affinity Modulations by Multiple Phosphorylation Occurring in the BIN1 SH3 Domain Binding Site of the Tau Protein Proline-Rich Region

2023 · Alessia Lasorsa, Krishnendu Bera, et al. · Biochemistry · 7

Signal transduction by BvgS sensor kinase. BINDING OF MODULATOR NICOTINATE AFFECTS THE CONFORMATION AND DYNAMICS OF THE ENTIRE PERIPLASMIC MOIETY.

2015 · Elian Dupré, Elodie Lesne, et al. · Journal of Biological Chemistry · 7

Tanycytes are degraded in Alzheimer’s Disease, disrupting the brain-to-blood efflux of Tau

2022 · Florent Sauvé, Gaëtan Ternier, et al. · medRxiv · 6

Tau profiling of brain extracellular vesicles reveals PHF6 peptide as core for pathological tau seeding in Alzheimer's disease

2026 · Marie Oosterlynck, Laura Fichter, et al. · Journal of Biomedical Science · 1

Anti-tau VHH therapy against PHF6: a safe approach to slowing the phenotype of tau pathology

2025 · Raphaelle Caillierez, Clémence Leboullenger, et al. · Alzheimer s Research & Therapy · 1

Works count: 57

Citation count: 570

H-index: 14

I10-index: 20