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Morihiro Mitsuya

Observed names: M. MITSUYA, M. Mitsuya, Mitsuya, M.
OpenAlex ID: A5047495331
Structural Basis for Allosteric Regulation of the Monomeric Allosteric Enzyme Human Glucokinase
2004 · Kenji Kamata, Morihiro Mitsuya, et al. · Structure · 503
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In Vitro Pharmacological Characterization of Novel Isoxazolopyridone Derivatives as Allosteric Metabotropic Glutamate Receptor 7 Antagonists
2007 · Gentaroh Suzuki, Naohiro Tsukamoto, et al. · Journal of Pharmacology and Experimental Therapeutics · 132
Imidazopyridine derivatives as potent and selective Polo-like kinase (PLK) inhibitors
2009 · Yoshiyuki Sato, Yu Onozaki, et al. · Bioorganic & Medicinal Chemistry Letters · 51
J-104129, a novel muscarinic M3 receptor antagonist with high selectivity for M3 over M2 receptors
1999 · Morihiro Mitsuya, Toshiaki Mase, et al. · Bioorganic & Medicinal Chemistry · 48
A Potent, Long-Acting, Orally Active (2R)-2-[(1R)-3,3-Difluorocyclopentyl]-2-hydroxy-2-phenylacetamide: A Novel Muscarinic M3 Receptor Antagonist with High Selectivity for M3 over M2 Receptors
2000 · Morihiro Mitsuya, Kensuke Kobayashi, et al. · Journal of Medicinal Chemistry · 46
Discovery of novel 3,6-disubstituted 2-pyridinecarboxamide derivatives as GK activators
2009 · Morihiro Mitsuya, Kenji Kamata, et al. · Bioorganic & Medicinal Chemistry Letters · 44
Identification of novel and potent 2-amino benzamide derivatives as allosteric glucokinase activators
2009 · Teruyuki Nishimura, Tomoharu Iino, et al. · Bioorganic & Medicinal Chemistry Letters · 44
Discovery and structure–activity relationships of a novel class of quinazoline glucokinase activators
2009 · Tomoharu Iino, Yasuhiro Sasaki, et al. · Bioorganic & Medicinal Chemistry Letters · 42
Isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists
2009 · Masayuki Nakamura, Hideki Kurihara, et al. · Bioorganic & Medicinal Chemistry Letters · 36
Diastereoselective Synthesis of the Acid Part of a New Muscarinic M3 Receptor Antagonist
2000 · Morihiro Mitsuya, Yoshio Ogino, et al. · Tetrahedron · 21
Stereoselective synthesis of a new muscarinic M3 receptor antagonist, J-104129
1999 · Morihiro Mitsuya, Kumiko Kawakami, et al. · Bioorganic & Medicinal Chemistry Letters · 21
TAS-119, a novel selective Aurora A and TRK inhibitor, exhibits antitumor efficacy in preclinical models with deregulated activation of the Myc, β-Catenin, and TRK pathways
2021 · Akihiro Miura, Hiroshi Sootome, et al. · Investigational New Drugs · 20
Synthesis and biological activity of J-104,118, a novel, potent inhibitor of squalene synthase
1995 · Yoshikazu Iwasawa, Masahiro Hayashi, et al. · Bioorganic & Medicinal Chemistry Letters · 20
Discovery of a muscarinic M3 receptor antagonist with high selectivity for M3 over M2 receptors among 2-[(1S,3S)-3-sulfonylaminocyclopentyl]phenylacetamide derivatives
2000 · Morihiro Mitsuya, Yoshio Ogino, et al. · Bioorganic & Medicinal Chemistry · 18
J-104,123, a novel and orally-active inhibitor of squalene synthase: Stereoselective synthesis and cholesterol lowering effects in dogs
1996 · Yoshikazu Iwasawa, Jun Shibata, et al. · Bioorganic & Medicinal Chemistry Letters · 18
Pharmacological Properties of (2R)-N-[1-(6-Aminopyridin-2-ylmethyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2- hydroxy-2-phenylacetamide: A Novel Muscarinic Antagonist with M2-Sparing Antagonistic Activity
2001 · Hiroyasu Hirose, Ikuo Aoki, et al. · Journal of Pharmacology and Experimental Therapeutics · 15
Discovery of 2-Aminothiazole-4-carboxamides, a Novel Class of Muscarinic M3 Selective Antagonists, through Solution-Phase Parallel Synthesis
2005 · Yufu Sagara, Morihiro Mitsuya, et al. · Chemical and Pharmaceutical Bulletin · 12
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Regio- and Facial-Selective Effects of Allylic Heteroatoms in 1,3-Dipolar Cycloaddition of a Nitrile Oxide
1990 · Yoshinobu Inouye, Morihiro Mitsuya, et al. · Bulletin of the Chemical Society of Japan · 9
Preparation of 2-Oxabicyclo[2.2.2]oct-5-ene, 1,4-Dimethyl-2-oxabicyclo[2.2.2]oct-5-ene, and 6-Oxabicyclo[3.2.1]oct-3-ene
1990 · Yoshinobu Inouye, Kenji Tokuhisa, et al. · Bulletin of the Chemical Society of Japan · 2
THU0058 Tas8274, a highly selective janus kinase 3 inhibitor, shows potent efficacy, but does not affect host defense, in preclinical mouse models
2018 · H. Hayashi, S. Demizu, et al. · Annals of the Rheumatic Diseases · 1
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ChemInform Abstract: Isoxazolopyridone Derivatives as Allosteric Metabotropic Glutamate Receptor 7 Antagonists.
2010 · Masayuki Nakamura, Hideki Kurihara, et al. · ChemInform
Allosteric Metabotropic Glutamate Receptor 7 Antagonists In Vitro Pharmacological Characterization of Novel Isoxazolopyridone Derivatives as
2010 · Annalisa Scimemi, Stéphanie Schorge, et al.
Discovery of 2‐Aminothiazole‐4‐carboxamides, a Novel Class of Muscarinic M3 Selective Antagonists, Through Solution‐Phase Parallel Synthesis.
2005 · Yufu Sagara, Morihiro Mitsuya, et al. · ChemInform
ChemInform Abstract: Diastereoselective Synthesis of the Acid Part of a New Muscarinic M3 Receptor Antagonist.
2001 · Morihiro Mitsuya, Yoshio Ogino, et al. · ChemInform
CCDC 134179: Experimental Crystal Structure Determination
2001 · Mitsuya, M., Kawakami, K., et al. · The Cambridge Structural Database
Works count: 32
Citation count: 1,103
H-index: 15
I10-index: 17
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