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E. Jon Jacobsen

Observed names: E J Jacobsen, E Jon Jacobsen, E. J. JACOBSEN, E. J. Jacobsen, E. Jacobsen, E. Jon. Jacobsen, E.J. Jacobsen, E.Jon Jacobsen
OpenAlex ID: A5048833502
Novel 21-amino steroids as potent inhibitors of iron-dependent lipid peroxidation.
1987 · J M Braughler, J F Pregenzer, et al. · Journal of Biological Chemistry · 465
Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6
2010 · Jill E. Chrencik, Akshay Patny, et al. · Journal of Molecular Biology · 231
Discovery ofN-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an Agonist of the α7 Nicotinic Acetylcholine Receptor, for the Potential Treatment of Cognitive Deficits in Schizophrenia: Synthesis and Structure−Activity Relationship
2006 · Donn G. Wishka, Daniel P. Walker, et al. · Journal of Medicinal Chemistry · 193
U-78517F: a potent inhibitor of lipid peroxidation with activity in experimental brain injury and ischemia.
1991 · E D Hall, J M Braughler, et al. · Journal of Pharmacology and Experimental Therapeutics · 149
The 21-aminosteroids: Potent inhibitors of lipid peroxidation for the treatment of central nervous system trauma and ischemia
1989 · J.M. Braughler, E.D. Hall, et al. · Drugs of the Future · 126
The Hepatitis B Virus Ribonuclease H Is Sensitive to Inhibitors of the Human Immunodeficiency Virus Ribonuclease H and Integrase Enzymes
2013 · John E. Tavis, Xiaohong Cheng, et al. · PLoS Pathogens · 106
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Selective inhibition of the p38α MAPK–MK2 axis inhibits inflammatory cues including inflammasome priming signals
2018 · Chun Wang, Susan Hockerman, et al. · The Journal of Experimental Medicine · 103
Design, synthesis, structure–activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists
2006 · Daniel P. Walker, Donn G. Wishka, et al. · Bioorganic & Medicinal Chemistry · 95
3-Phenyl-Substituted Imidazo[1,5-a]quinoxalin-4-ones and Imidazo[1,5-a]quinoxaline Ureas That Have High Affinity at the GABAA/Benzodiazepine Receptor Complex
1996 · E. Jon Jacobsen, Lindsay S. Stelzer, et al. · Journal of Medicinal Chemistry · 92
Novel membrane localized iron chelators as inhibitors of iron-dependent lipid peroxidation
1988 · J.Mark Braughler, Philip S. Burton, et al. · Biochemical Pharmacology · 88
Novel 21-aminosteroids that inhibit iron-dependent lipid peroxidation and protect against central nervous system trauma
1990 · E. Jon Jacobsen, John M. McCall, et al. · Journal of Medicinal Chemistry · 87
Chair topology of the palladium dichloride catalyzed Cope rearrangement of acyclic 1,5-dienes
1982 · Larry E. Overman, E. Jon Jacobsen · Journal of the American Chemical Society · 83
Synthesis applications of aza-Cope rearrangements. 12. Applications of cationic aza-Cope rearrangements for alkaloid synthesis. Stereoselective preparation of cis-3a-aryloctahydroindoles and a new short route to Amaryllidaceae alkaloids
1983 · Larry E. Overman, Leah T. Mendelson, et al. · Journal of the American Chemical Society · 73
Synthesis applications of cationic aza-Cope rearrangements. Part 18. Scope and mechanism of tandem cationic aza-Cope rearrangement-Mannich cyclization reactions
1988 · E. Jon. Jacobsen, Jeremy. Levin, et al. · Journal of the American Chemical Society · 70
Piperazine Imidazo[1,5-a]quinoxaline Ureas as High-Affinity GABAALigands of Dual Functionality
1999 · E. Jon Jacobsen, Lindsay S. Stelzer, et al. · Journal of Medicinal Chemistry · 68
High-Affinity Partial Agonist Imidazo[1,5-a]quinoxaline Amides, Carbamates, and Ureas at the γ-Aminobutyric Acid A/Benzodiazepine Receptor Complex
1996 · E. Jon Jacobsen, Ruth E. TenBrink, et al. · Journal of Medicinal Chemistry · 67
Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the α7 nicotinic acetylcholine receptor: In vitro and in vivo activity
2008 · Brad A. Acker, E. Jon Jacobsen, et al. · Bioorganic & Medicinal Chemistry Letters · 61
Synthesis of a Series of Stromelysin-Selective Thiadiazole Urea Matrix Metalloproteinase Inhibitors
1999 · E. Jon Jacobsen, Mark A. Mitchell, et al. · Journal of Medicinal Chemistry · 58
Enantioselective syntheses of (+)-α-skytanthine, (+)-δ-skytanthine and (+)-iridomyrmecin by an intramolecular magnesium-ene reaction.
1986 · Wolfgang Oppolzer, E.Jon Jacobsen · Tetrahedron Letters · 53
Asymmetric Synthesis of 2,6-Methylated Piperazines
1995 · John W. Mickelson, Kenneth L. Belonga, et al. · The Journal of Organic Chemistry · 50
Oxidative cyclization of acyclic ureas with bis(trifluoroacetoxy)iodobenzene to generate N-substituted 2-benzimidazolinones
1996 · Arthur G. Romero, William H. Darlington, et al. · Tetrahedron Letters · 44
Nonsteroidal lazaroid U78517F in models of focal and global ischemia.
1990 · E D Hall, K E Pazara, et al. · PubMed · 43
Evaluation of Aminohydantoins as a Novel Class of Antimalarial Agents
2013 · Marvin J. Meyers, Micky D. Tortorella, et al. · ACS Medicinal Chemistry Letters · 42
High-Affinity α-Aminobutyric Acid A/Benzodiazepine Ligands: Synthesis and Structure−Activity Relationship Studies of a New Series of Tetracyclic Imidazoquinoxalines
1996 · John W. Mickelson, E. Jon Jacobsen, et al. · Journal of Medicinal Chemistry · 42
2-(Aminomethyl)chromans that inhibit iron-dependent lipid peroxidation and protect against central nervous system trauma and ischemia
1992 · E. Jon Jacobsen, Fred J. VanDoornik, et al. · Journal of Medicinal Chemistry · 32
Works count: 71
Citation count: 2,962
H-index: 28
I10-index: 45
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