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Richard J. Sové

Observed names: R.J. Sove, Richard J Sove, Richard J Sové, Richard J. Sove, Richard Sove, Sove, Richard J.
ORCID: 0000-0003-1491-616X
Observed ORCID: 0000-0003-1491-616X
OpenAlex ID: A5048835954
Rapid desiccation hardening changes the cuticular hydrocarbon profile of Drosophila melanogaster
2014 · Joseph R. Stinziano, Richard J. Sové, et al. · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · 89
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Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model
2022 · Alvaro Ruiz-Martinez, Chang Gong, et al. · PLoS Computational Biology · 62
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A mechanistic integrative computational model of macrophage polarization: Implications in human pathophysiology
2019 · Chen Zhao, Adam C. Mirando, et al. · PLoS Computational Biology · 60
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QSP‐IO: A Quantitative Systems Pharmacology Toolbox for Mechanistic Multiscale Modeling for Immuno‐Oncology Applications
2020 · Richard J. Sové, Mohammad Jafarnejad, et al. · CPT Pharmacometrics & Systems Pharmacology · 57
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Quantitative systems pharmacology model predictions for efficacy of atezolizumab and nab-paclitaxel in triple-negative breast cancer
2021 · Hanwen Wang, Huilin Ma, et al. · Journal for ImmunoTherapy of Cancer · 53
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Combination therapy with T cell engager and PD-L1 blockade enhances the antitumor potency of T cells as predicted by a QSP model
2020 · Huilin Ma, Hanwen Wang, et al. · Journal for ImmunoTherapy of Cancer · 51
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Conducting a Virtual Clinical Trial in HER2-Negative Breast Cancer Using a Quantitative Systems Pharmacology Model With an Epigenetic Modulator and Immune Checkpoint Inhibitors
2020 · Hanwen Wang, Richard J. Sové, et al. · Frontiers in Bioengineering and Biotechnology · 51
Virtual clinical trials of anti-PD-1 and anti-CTLA-4 immunotherapy in advanced hepatocellular carcinoma using a quantitative systems pharmacology model
2022 · Richard J Sové, Babita K Verma, et al. · Journal for ImmunoTherapy of Cancer · 48
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A Quantitative Systems Pharmacology Model of T Cell Engager Applied to Solid Tumor
2020 · Huilin Ma, Hanwen Wang, et al. · The AAPS Journal · 47
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A data-driven computational model enables integrative and mechanistic characterization of dynamic macrophage polarization
2021 · Chen Zhao, Thalyta X. Medeiros, et al. · iScience · 44
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Mechanistically detailed systems biology modeling of the HGF/Met pathway in hepatocellular carcinoma
2019 · Mohammad Jafarnejad, Richard J. Sové, et al. · npj Systems Biology and Applications · 29
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Spectroscopy detects skeletal muscle microvascular dysfunction during onset of sepsis in a rat fecal peritonitis model
2022 · Paulina M. Kowalewska, Justin E. Kowalewski, et al. · Scientific Reports · 14
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Localized Oxygen Exchange Platform for Intravital Video Microscopy Investigations of Microvascular Oxygen Regulation
2021 · Richard J. Sové, Stephanie Milkovich, et al. · Frontiers in Physiology · 11
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A computational model of the effect of capillary density variability on oxygen transport, glucose uptake, and insulin sensitivity in prediabetes
2016 · Richard J. Sové, Daniel Goldman, et al. · Microcirculation · 10
A Computational Model of a Microfluidic Device to Measure the Dynamics of Oxygen-Dependent ATP Release from Erythrocytes
2013 · Richard J. Sove, Nour Ghonaim, et al. · PLoS ONE · 10
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Finite Element Model of Oxygen Transport for the Design of Geometrically Complex Microfluidic Devices Used in Biological Studies
2016 · Richard J. Sové, Graham M. Fraser, et al. · PLoS ONE · 7
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Development of thin-film micro-outlets for spatially constraining local PO2 perturbations to capillaries in vivo
2025 · Meghan E. Kiley, Richard J. Sové, et al. · Frontiers in Physiology · 2
Optical method to determine in vivo capillary hematocrit, hemoglobin concentration, and 3‐D network geometry in skeletal muscle
2022 · Jaryd R. Christie, Isaac Kong, et al. · Microcirculation · 2
Development and validation of a novel microfluidic device for the manipulation of skeletal muscle microvascular blood flow in vivo
2021 · Gaylene M. Russell McEvoy, Hamza Shogan, et al. · Microcirculation · 2
Integrated Transcriptomic and Proteomic Analyses Reveal Role of the Hexosamine Biosynthetic Pathway in Invasion and Metastasis of Hepatocellular Carcinoma
2020 · C. Lam, M.A. Barbhuiya, et al. · International Journal of Radiation Oncology*Biology*Physics
Simulations of Combination Therapy in Hepatocellular Carcinoma Using a Quantitative Systems Pharmacology Model
2020 · Richard J. Sove, Mohammad Jafarnejad, et al. · The FASEB Journal
Computational Model to Predict Tissue Concentration of Drugs Delivered via Intravital Fluid Exchange Devices
2020 · Richard J. Sové, Gaylene M. Russell McEvoy, et al. · The FASEB Journal
Using digital inpainting to estimate incident light intensity for the calculation of red blood cell oxygen saturation from microscopy images
2018 · Richard J. Sové, Nicole E. Drakos, et al. · Journal of Biophotonics
Methods for the Investigation of Microvascular Control of Oxygen Distribution
2018 · Richard J. Sové · Scholarship@Western (Western University)
Oxygen Considerations in the Design of Microfluidics for Studying Oxygen Dependent ATP Release from Erythrocytes
2016 · Richard J Sove, Daniel Goldman, et al. · The FASEB Journal
Works count: 28
Citation count: 649
H-index: 12
I10-index: 15
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