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Thomas A. Leonard
Observed names:
Leonard, Thomas,
T. Leonard,
T.A. Leonard,
Thomas A Leonard,
Thomas Leonard,
Thomas A. Leonard
show all 6
Institutions:
University of Vienna,
Max Perutz Labs,
Medical University of Vienna
Observed institutions:
University of Vienna,
National Institutes of Health,
MRC Laboratory of Molecular Biology,
Max Perutz Labs,
National Institute of Diabetes and Digestive and Kidney Diseases,
Vienna Biocenter,
Bioinformatics Institute,
Medical University of Vienna
show all 8
ORCID:
0000-0001-6853-666X
Observed ORCID:
0000-0001-6853-666X
OpenAlex ID:
A5048866718
Coiled‐coils: The long and short of it
2016
·
Linda Truebestein
, Thomas A. Leonard
·
BioEssays
·
335
PDF
Bacterial chromosome segregation: structure and DNA binding of the Soj dimer — a conserved biological switch
2005
·
Thomas A Leonard
, P Jonathan Butler
, et al.
·
The EMBO Journal
·
304
PDF
PI(3,4,5)P 3 Engagement Restricts Akt Activity to Cellular Membranes
2017
·
Michael Ebner
, Iva Lučić
, et al.
·
Molecular Cell
·
217
PDF
Crystal Structure and Allosteric Activation of Protein Kinase C βII
2011
·
Thomas A. Leonard
, Bartosz Różycki
, et al.
·
Cell
·
184
PDF
Features critical for membrane binding revealed by DivIVA crystal structure
2010
·
Maria A Oliva
, Sven Halbedel
, et al.
·
The EMBO Journal
·
128
PDF
Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation
2022
·
Aleksandra Levina
, Kaelin D. Fleming
, et al.
·
Nature Communications
·
109
PDF
Structural analysis of the chromosome segregation protein Spo0J from Thermus thermophilus
2004
·
Thomas A. Leonard
, P. Jonathan G. Butler
, et al.
·
Molecular Microbiology
·
104
Conformational sampling of membranes by Akt controls its activation and inactivation
2018
·
Iva Lučić
, Manoj K. Rathinaswamy
, et al.
·
Proceedings of the National Academy of Sciences
·
101
Structure of autoinhibited Akt1 reveals mechanism of PIP 3 -mediated activation
2021
·
Linda Truebestein
, Harald Hornegger
, et al.
·
Proceedings of the National Academy of Sciences
·
90
A critical evaluation of protein kinase regulation by activation loop autophosphorylation
2023
·
Ronja Reinhardt
, Thomas A Leonard
·
eLife
·
77
PDF
Towards understanding the molecular basis of bacterial DNA segregation
2005
·
Thomas A Leonard
, Jakob M⊘ller-Jensen
, et al.
·
Philosophical Transactions of the Royal Society B Biological Sciences
·
77
A molecular ruler regulates cytoskeletal remodelling by the Rho kinases
2015
·
Linda Truebestein
, Daniel J. Elsner
, et al.
·
Nature Communications
·
74
PDF
Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes
2010
·
Yuliang Wu
, Joshua A. Sommers
, et al.
·
Blood
·
72
Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations
2018
·
Ratna Tripathy
, Ines Leca
, et al.
·
Neuron
·
60
PDF
Regulation of protein kinases by lipids
2011
·
Thomas A Leonard
, James H Hurley
·
Current Opinion in Structural Biology
·
59
The membrane surface as a platform that organizes cellular and biochemical processes
2023
·
Thomas A. Leonard
, Martin Loose
, et al.
·
Developmental Cell
·
56
Lipid-dependent Akt-ivity: where, when, and how
2019
·
Katharina M. Siess
, Thomas A. Leonard
·
Biochemical Society Transactions
·
40
Novel Features of DAG-Activated PKC Isozymes Reveal a Conserved 3-D Architecture
2015
·
Iva Lučić
, Linda Truebestein
, et al.
·
Journal of Molecular Biology
·
37
ATP-competitive and allosteric inhibitors induce differential conformational changes at the autoinhibitory interface of Akt1
2023
·
Alexandria L. Shaw
, Matthew A.H. Parson
, et al.
·
Structure
·
24
A switch in nucleotide affinity governs activation of the Src and Tec family kinases
2017
·
Freia von Raußendorf
, Anita de Ruiter
, et al.
·
Scientific Reports
·
23
PDF
Stabilizing the eIF4G1 α-Helix Increases Its Binding Affinity with eIF4E: Implications for Peptidomimetic Design Strategies
2010
·
C.J. Brown
, J.J. Lim
, et al.
·
Journal of Molecular Biology
·
23
A ubiquitin-like domain controls protein kinase D dimerization and activation by trans-autophosphorylation
2019
·
Daniel J. Elsner
, Katharina M. Siess
, et al.
·
Journal of Biological Chemistry
·
22
Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats
2020
·
Sara Sajko
, Irina Grishkovskaya
, et al.
·
PLoS ONE
·
20
PDF
It Takes Two to Tango: Activation of Protein Kinase D by Dimerization
2020
·
Ronja Reinhardt
, Linda Truebestein
, et al.
·
BioEssays
·
20
PDF
Made to measure – keeping Rho kinase at a distance
2016
·
Linda Truebestein
, Daniel J. Elsner
, et al.
·
Small GTPases
·
19
PDF
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Works count:
66
Citation count:
2,388
H-index:
22
I10-index:
30
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