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Author

Sarah M. Leonard

Observed names: S. Leonard, S. M. Leonard, Sarah Leonard
ORCID: 0000-0003-3752-7300
Observed ORCID: 0000-0003-3752-7300
OpenAlex ID: A5050007304
Oncogenic human papillomavirus imposes an instructive pattern of DNA methylation changes which parallel the natural history of cervical HPV infection in young women
2012 · S. M. Leonard, W. Wei, et al. · Carcinogenesis · 100
Down-regulation of BLIMP1α by the EBV oncogene, LMP-1, disrupts the plasma cell differentiation program and prevents viral replication in B cells: implications for the pathogenesis of EBV-associated B-cell lymphomas
2011 · Katerina Vrzalikova, Martina Vockerodt, et al. · Blood · 100
Epigenetic and Transcriptional Changes Which Follow Epstein-Barr Virus Infection of Germinal Center B Cells and Their Relevance to the Pathogenesis of Hodgkin's Lymphoma
2011 · Sarah Leonard, Wenbin Wei, et al. · Journal of Virology · 98
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Repurposing itraconazole for the treatment of cancer
2017 · Rachel Pounds, Sarah Leonard, et al. · Oncology Letters · 69
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Adjacent Lichen Sclerosis predicts local recurrence and second field tumour in women with vulvar squamous cell carcinoma
2016 · J.K.W. Yap, R. Fox, et al. · Gynecologic Oncology · 63
Immune‐Mobilizing Monoclonal T Cell Receptors Mediate Specific and Rapid Elimination of Hepatitis B–Infected Cells
2020 · Joannah R. Fergusson, Zoë Wallace, et al. · Hepatology · 50
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Association of an intact E2 gene with higher HPV viral load, higher viral oncogene expression, and improved clinical outcome in HPV16 positive head and neck squamous cell carcinoma
2018 · Nicole V. Anayannis, Nicolas F. Schlecht, et al. · PLoS ONE · 43
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Sequential Treatment with Cytarabine and Decitabine Has an Increased Anti-Leukemia Effect Compared to Cytarabine Alone in Xenograft Models of Childhood Acute Myeloid Leukemia
2014 · Sarah M. Leonard, Tracey Perry, et al. · PLoS ONE · 33
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Arginine Methyltransferases Are Regulated by Epstein-Barr Virus in B Cells and Are Differentially Expressed in Hodgkin’s Lymphoma
2012 · Sarah Leonard, Naheema Gordon, et al. · Pathogens · 27
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Over-expression of DNMT3A predicts the risk of recurrent vulvar squamous cell carcinomas
2016 · Sarah Leonard, Merlin Pereira, et al. · Gynecologic Oncology · 26
Structure‐guided stabilization of pathogen‐derived peptide‐HLA‐E complexes using non‐natural amino acids conserves native TCR recognition
2022 · Claire Barber, Victoria Arena De Souza, et al. · European Journal of Immunology · 25
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Evidence of disrupted high-risk human papillomavirus DNA in morphologically normal cervices of older women
2016 · Sarah M. Leonard, Merlin Pereira, et al. · Scientific Reports · 22
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An HLA-E-targeted TCR bispecific molecule redirects T cell immunity against Mycobacterium tuberculosis
2024 · Rachel L. Paterson, Marco P. La Manna, et al. · Proceedings of the National Academy of Sciences · 17
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Instability of the HLA-E peptidome of HIV presents a major barrier to therapeutic targeting
2024 · Zoë Wallace, Tiaan Heunis, et al. · Molecular Therapy · 16
Hypomethylation and Over-Expression of the Beta Isoform of BLIMP1 is Induced by Epstein-Barr Virus Infection of B Cells; Potential Implications for the Pathogenesis of EBV-Associated Lymphomas
2012 · Katerina Vrzalikova, Sarah Leonard, et al. · Pathogens · 11
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Viral sequence determines HLA-E-restricted T cell recognition of hepatitis B surface antigen
2024 · Gavuthami Murugesan, Rachel L. Paterson, et al. · Nature Communications · 9
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Use of a genome-wide haploid genetic screen to identify treatment predicting factors: a proof-of-principle study in pancreatic cancer
2017 · Yuk Ting Ma, Sarah M. Leonard, et al. · Oncotarget · 5
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894 Discovery and preclinical development of a half-life-extended TCR-based bispecific T cell engager targeting a novel cancer antigen presented across multiple solid tumor indications
2026 · Dominic Hine, Samhita Rao, et al. · Journal for ImmunoTherapy of Cancer
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891 Pre-clinical development of a best-in-class bispecific T cell engager targeting a highly abundant peptide for the treatment of melanoma
2026 · Samantha Drennan, Jong Fu Wong, et al. · Journal for ImmunoTherapy of Cancer
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Abstract 3506: Clinic enabling development of a TCR-Ab half life extended T cell engager against a novel solid tumor target
2025 · Sarah Leonard, Hemza Ghadbane, et al. · Cancer Research
Abstract 7438: Mapping T cell reactivity against the human genome using machine learning uncovers target specific TCRs against novel tumour antigens
2025 · Nathaniel J. Davies, Amalia Martinez, et al. · Cancer Research
1294 Engineering a T cell receptor (TCR) into an antibody drug format provides a novel approach to half-life extended T cell engagers targeting PRAME A2 and PRAME A24
2024 · Hemza Ghadbane, Dominic Hine, et al. · Journal for ImmunoTherapy of Cancer
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1206 Profiling the dark genome of tumours provides new potential therapies for cancer patients
2024 · Nathaniel J Davies, Samantha Drennan, et al. · Journal for ImmunoTherapy of Cancer
A haploid genetic screen identifies the key determinant of response to novel combination therapy with gemcitabine and entinostat in pancreatic cancer.
2016 · Yuk Ting Ma, Sarah Leonard, et al. · Journal of Clinical Oncology
An investigation of the epigenetic and transcriptional changes which follow Epstein-Barr virus infection of germinal centre B cells
2010 · Sarah Leonard · University of Birmingham Institutional Research Archive (University of Birmingham)
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Works count: 25
Citation count: 714
H-index: 14
I10-index: 15
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