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Neal Green

2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition
2016 · Soojay Banerjee, Alberto Bartesaghi, et al. · Science · 344
Pharmacologic Inhibition of Tpl2 Blocks Inflammatory Responses in Primary Human Monocytes, Synoviocytes, and Blood
2007 · J. Perry Hall, Yahya Kurdi, et al. · Journal of Biological Chemistry · 79
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Inhibition of Tpl2 kinase and TNFα production with quinoline-3-carbonitriles for the treatment of rheumatoid arthritis
2006 · Yonghan Hu, Neal Green, et al. · Bioorganic & Medicinal Chemistry Letters · 64
Inhibition of Tpl2 kinase and TNF-α production with 1,7-naphthyridine-3-carbonitriles: Synthesis and structure–activity relationships
2005 · Lori Krim Gavrin, Neal Green, et al. · Bioorganic & Medicinal Chemistry Letters · 51
Inhibitors of Tumor Progression Loci-2 (Tpl2) Kinase and Tumor Necrosis Factor α (TNF-α) Production: Selectivity and in Vivo Antiinflammatory Activity of Novel 8-Substituted-4-anilino-6-aminoquinoline-3-carbonitriles
2007 · Neal Green, Yonghan Hu, et al. · Journal of Medicinal Chemistry · 46
Selective inhibitors of tumor progression loci-2 (Tpl2) kinase with potent inhibition of TNF-α production in human whole blood
2009 · Junjun Wu, Neal Green, et al. · Bioorganic & Medicinal Chemistry Letters · 42
Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway
2015 · Celeste Alverez, Stacie L. Bulfer, et al. · ACS Medicinal Chemistry Letters · 33
Benzhydrylquinazolinediones: Novel cytosolic phospholipase A2α inhibitors with improved physicochemical properties
2009 · Steven J. Kirincich, Jason Xiang, et al. · Bioorganic & Medicinal Chemistry · 31
Identification of a novel class of selective Tpl2 kinase inhibitors: 4-Alkylamino-[1,7]naphthyridine-3-carbonitriles
2007 · Neelu Kaila, Neal Green, et al. · Bioorganic & Medicinal Chemistry · 27
Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97
2018 · Matthew G. LaPorte, James C. Burnett, et al. · ACS Medicinal Chemistry Letters · 26
A rat pharmacokinetic/pharmacodynamic model for assessment of lipopolysaccharide-induced tumor necrosis factor-alpha production
2007 · Qin Wang, Yuhua Zhang, et al. · Journal of Pharmacological and Toxicological Methods · 18
Optimization of 1,2,4-Triazole-Based p97 Inhibitors for the Treatment of Cancer
2023 · Matthew G. LaPorte, Celeste Alverez, et al. · ACS Medicinal Chemistry Letters · 12
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Inhibition of Tpl2 Kinase and TNF‐α Production with 1,7‐Naphthyridine‐3‐carbonitriles: Synthesis and Structure—Activity Relationships.
2006 · Neal Green, et al. et al. · ChemInform · 8
Antitumor Efficacy of 1,2,4-Triazole-Based VCP/p97 Allosteric Inhibitors
2025 · Neal Green, Matthew G. LaPorte, et al. · Journal of Medicinal Chemistry · 7
Optimization of ether and aniline based inhibitors of lactate dehydrogenase
2021 · Plamen P. Christov, Kwangho Kim, et al. · Bioorganic & Medicinal Chemistry Letters · 5
Works count: 15
Citation count: 793
H-index: 12
I10-index: 12
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