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Sarah Batey

The folding and evolution of multidomain proteins
2007 · Jung-Hoon Han, Sarah Batey, et al. · Nature Reviews Molecular Cell Biology · 412
Experimental evidence for a frustrated energy landscape in a three-helix-bundle protein family
2010 · Beth G. Wensley, Sarah Batey, et al. · Nature · 160
FS118, a Bispecific Antibody Targeting LAG-3 and PD-L1, Enhances T-Cell Activation Resulting in Potent Antitumor Activity
2020 · Matthew Kraman, Mustapha Faroudi, et al. · Clinical Cancer Research · 112
Discovery and characterization of COVA322, a clinical-stage bispecific TNF/IL-17A inhibitor for the treatment of inflammatory diseases
2015 · Michela Silacci, Wibke Lembke, et al. · mAbs · 94
Studying the folding of multidomain proteins
2008 · Sarah Batey, Adrian A. Nickson, et al. · HFSP journal · 75
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Cooperative Folding in a Multi-domain Protein
2005 · Sarah Batey, Lucy G. Randles, et al. · Journal of Molecular Biology · 72
The Folding of Spectrin Domains I: Wild-type Domains Have the Same Stability but very Different Kinetic Properties
2004 · Kathryn A. Scott, Sarah Batey, et al. · Journal of Molecular Biology · 68
Apparent cooperativity in the folding of multidomain proteins depends on the relative rates of folding of the constituent domains
2006 · Sarah Batey, Jane Clarke · Proceedings of the National Academy of Sciences · 66
FS222, a CD137/PD-L1 Tetravalent Bispecific Antibody, Exhibits Low Toxicity and Antitumor Activity in Colorectal Cancer Models
2020 · Matthew A. Lakins, Alexander Koers, et al. · Clinical Cancer Research · 65
Complex Folding Kinetics of a Multidomain Protein
2005 · Sarah Batey, Kathryn A. Scott, et al. · Biophysical Journal · 60
Linker Length Matters, Fynomer-Fc Fusion with an Optimized Linker Displaying Picomolar IL-17A Inhibition Potency
2014 · Michela Silacci, Nadja Baenziger-Tobler, et al. · Journal of Biological Chemistry · 59
Generation, characterization and structural data of chymase binding proteins based on the human Fyn kinase SH3 domain
2012 · Daniel Schlatter, Simon Brack, et al. · mAbs · 44
The Folding Pathway of a Single Domain in a Multidomain Protein is not Affected by Its Neighbouring Domain
2008 · Sarah Batey, Jane Clarke · Journal of Molecular Biology · 42
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Different Members of a Simple Three-Helix Bundle Protein Family Have Very Different Folding Rate Constants and Fold by Different Mechanisms
2009 · Beth G. Wensley, Martina Gärtner, et al. · Journal of Molecular Biology · 36
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A HER2-specific Modified Fc Fragment (Fcab) Induces Antitumor Effects Through Degradation of HER2 and Apoptosis
2015 · Kin-Mei Leung, Sarah Batey, et al. · Molecular Therapy · 35
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Distinguishing Specific and Nonspecific Interdomain Interactions in Multidomain Proteins
2007 · Lucy G. Randles, Sarah Batey, et al. · Biophysical Journal · 19
Abstract 4547: Clustering CD137 via cell-expressed PD-L1 crosslinking avoided Fc-mediated agonism and resulted in safe and potent conditional lymphocyte activation
2020 · Matthew A. Lakins, Alexander Koers, et al. · Cancer Research · 1
Abstract 1540: FS222 mAb2, a bispecific conditional agonist antibody targeting CD137 and PD-L1, induces potent lymphocyte activation and has a favorable safety profile
2019 · Matthew A. Lakins, Alexander Koers, et al. · Immunology · 1
Abstract 1540: FS222 mAb2, a bispecific conditional agonist antibody targeting CD137 and PD-L1, induces potent lymphocyte activation and has a favorable safety profile
2019 · Matthew A. Lakins, Alexander Koers, et al. · Cancer Research · 1
Abstract B123: Preclinical evaluation of FS102: A HER2-specific Fcab with a novel mechanism of action.
2013 · Sarah Batey, Kinmei Leung, et al. · Molecular Cancer Therapeutics · 1
Combined Supplementary Data from FS222, a CD137/PD-L1 Tetravalent Bispecific Antibody, Exhibits Low Toxicity and Antitumor Activity in Colorectal Cancer Models
2023 · Matthew A. Lakins, Alexander Koers, et al.
Combined Supplementary Data from FS222, a CD137/PD-L1 Tetravalent Bispecific Antibody, Exhibits Low Toxicity and Antitumor Activity in Colorectal Cancer Models
2023 · Matthew A. Lakins, Alexander Koers, et al.
Kraman et al Supplementary Data from FS118, a Bispecific Antibody Targeting LAG-3 and PD-L1, Enhances T-Cell Activation Resulting in Potent Antitumor Activity
2023 · Matthew Kraman, Mustapha Faroudi, et al.
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Data from FS118, a Bispecific Antibody Targeting LAG-3 and PD-L1, Enhances T-Cell Activation Resulting in Potent Antitumor Activity
2023 · Matthew Kraman, Mustapha Faroudi, et al.
Data from FS222, a CD137/PD-L1 Tetravalent Bispecific Antibody, Exhibits Low Toxicity and Antitumor Activity in Colorectal Cancer Models
2023 · Matthew A. Lakins, Alexander Koers, et al.
Works count: 29
Citation count: 1,423
H-index: 16
I10-index: 16
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