Get started
Author

Jacqueline M. Tremblay

Observed names: J.M. Tremblay, Jacqueline M Tremblay, Jacqueline Tremblay
Institution: Tufts University
OpenAlex ID: A5054040744
Structure of a Multifunctional Protein
2001 · Marilyn D. Yoder, Leonard M. Thomas, et al. · Journal of Biological Chemistry · 137
Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut
2023 · Jason P. Lynch, Coral González-Prieto, et al. · Cell Host & Microbe · 128
A Novel Multivalent, Single-Domain Antibody Targeting TcdA and TcdB Prevents Fulminant Clostridium difficile Infection in Mice
2014 · Zhiyong Yang, Diane Schmidt, et al. · The Journal of Infectious Diseases · 104
PDF
A Single VHH-Based Toxin-Neutralizing Agent and an Effector Antibody Protect Mice against Challenge with Shiga Toxins 1 and 2
2013 · Jacqueline M. Tremblay, Jean Mukherjee, et al. · Infection and Immunity · 103
A Novel Strategy for Development of Recombinant Antitoxin Therapeutics Tested in a Mouse Botulism Model
2012 · Jean Mukherjee, Jacqueline M. Tremblay, et al. · PLoS ONE · 92
PDF
Camelid single domain antibodies (VHHs) as neuronal cell intrabody binding agents and inhibitors of Clostridium botulinum neurotoxin (BoNT) proteases
2010 · Jacqueline M. Tremblay, Chueh-Ling Kuo, et al. · Toxicon · 83
Stepwise Engineering of Heterodimeric Single Domain Camelid VHH Antibodies That Passively Protect Mice from Ricin Toxin
2013 · David J. Vance, Jacqueline M. Tremblay, et al. · Journal of Biological Chemistry · 72
A Tetraspecific VHH-Based Neutralizing Antibody Modifies Disease Outcome in Three Animal Models of Clostridium difficile Infection
2016 · Diane J. Schmidt, Gillian Beamer, et al. · Clinical and Vaccine Immunology · 47
PDF
Structure of PITPβ in Complex with Phosphatidylcholine: Comparison of Structure and Lipid Transfer to Other PITP Isoforms,
2005 · Paul B. Vordtriede, Chuong N. Doan, et al. · Biochemistry · 42
Structural Insights into Rational Design of Single-Domain Antibody-Based Antitoxins against Botulinum Neurotoxins
2020 · Kwok-ho Lam, Jacqueline M. Tremblay, et al. · Cell Reports · 40
PDF
A Heterodimer of a VHH (Variable Domains of Camelid Heavy Chain-only) Antibody That Inhibits Anthrax Toxin Cell Binding Linked to a VHH Antibody That Blocks Oligomer Formation Is Highly Protective in an Anthrax Spore Challenge Model
2015 · Mahtab Moayeri, Clinton E. Leysath, et al. · Journal of Biological Chemistry · 39
PDF
Prolonged Prophylactic Protection from Botulism with a Single Adenovirus Treatment Promoting Serum Expression of a VHH-Based Antitoxin Protein
2014 · Jean Mukherjee, Igor Dmitriev, et al. · PLoS ONE · 37
PDF
Mechanisms of Ricin Toxin Neutralization Revealed through Engineered Homodimeric and Heterodimeric Camelid Antibodies
2015 · Cristina Herrera, Jacqueline M. Tremblay, et al. · Journal of Biological Chemistry · 36
A Diverse Set of Single-domain Antibodies (VHHs) against the Anthrax Toxin Lethal and Edema Factors Provides a Basis for Construction of a Bispecific Agent That Protects against Anthrax Infection
2016 · Catherine E. Vrentas, Mahtab Moayeri, et al. · Journal of Biological Chemistry · 35
PDF
Limited Proteolysis of Rat Phosphatidylinositol Transfer Protein by Trypsin Cleaves the C Terminus, Enhances Binding to Lipid Vesicles, and Reduces Phospholipid Transfer Activity
1996 · Jacqueline M. Tremblay, Helmkamp M. George, et al. · Journal of Biological Chemistry · 34
Affinity-tuned mesothelin CAR T cells demonstrate enhanced targeting specificity and reduced off-tumor toxicity
2024 · Yanping Yang, Yogindra Vedvyas, et al. · JCI Insight · 32
High-Resolution Epitope Positioning of a Large Collection of Neutralizing and Nonneutralizing Single-Domain Antibodies on the Enzymatic and Binding Subunits of Ricin Toxin
2017 · David J. Vance, Jacqueline M. Tremblay, et al. · Clinical and Vaccine Immunology · 32
Camelid VHH Antibodies that Neutralize Botulinum Neurotoxin Serotype E Intoxication or Protease Function
2020 · Jacqueline M. Tremblay, Edwin Vazquez-Cintron, et al. · Toxins · 29
PDF
Single-domain antibodies pinpoint potential targets within Shigella invasion plasmid antigen D of the needle tip complex for inhibition of type III secretion
2017 · Michael L. Barta, Jonathan P. Shearer, et al. · Journal of Biological Chemistry · 28
Schistosoma mansoni host-exposed surface antigens characterized by sera and recombinant antibodies from schistosomiasis-resistant rats
2010 · Jorge Sepulveda, Jacqueline M. Tremblay, et al. · International Journal for Parasitology · 28
Identification and characterization of a new 34 kDa MORN motif-containing sporozoite surface-exposed protein, Cp-P34, unique to Cryptosporidium
2021 · Justyna J. Jaskiewicz, Jacqueline M. Tremblay, et al. · International Journal for Parasitology · 26
Schistosoma mansoni Infection of Mice, Rats and Humans Elicits a Strong Antibody Response to a Limited Number of Reduction-Sensitive Epitopes on Five Major Tegumental Membrane Proteins
2017 · Greice Krautz-Peterson, Michelle Debatis, et al. · PLoS neglected tropical diseases · 25
PDF
Adenovirus Vector Expressing Stx1/Stx2-Neutralizing Agent Protects Piglets Infected with Escherichia coli O157:H7 against Fatal Systemic Intoxication
2014 · Abhineet S. Sheoran, Igor P. Dmitriev, et al. · Infection and Immunity · 25
PDF
Both isoforms of mammalian phosphatidylinositol transfer protein are capable of binding and transporting sphingomyelin
2002 · Hong Li, Jacqueline M Tremblay, et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 24
Adenoviral Expression of a Bispecific VHH-Based Neutralizing Agent That Targets Protective Antigen Provides Prophylactic Protection from Anthrax in Mice
2016 · Mahtab Moayeri, Jacqueline M. Tremblay, et al. · Clinical and Vaccine Immunology · 22
PDF
Works count: 53
Citation count: 1,486
H-index: 24
I10-index: 34
Year
Topic
Type