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T. Malia

Activation of Apoptosis in Vivo by a Hydrocarbon-Stapled BH3 Helix
2004 · Loren D. Walensky, Andrew L. Kung, et al. · Science · 1,346
Solution Structure of the Integral Human Membrane Protein VDAC-1 in Detergent Micelles
2008 · Sebastian Hiller, Robert G. Garces, et al. · Science · 666
NMR Structural Investigation of the Mitochondrial Outer Membrane Protein VDAC and Its Interaction with Antiapoptotic Bcl-xL
2006 · Thomas J. Malia, Gerhard Wagner · Biochemistry · 164
An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations
2013 · Omid Vafa, Gary L. Gilliland, et al. · Methods · 152
Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti‐tau antibody AT8
2016 · Thomas J. Malia, Alexey Teplyakov, et al. · Proteins Structure Function and Bioinformatics · 134
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Allelic variation in class I HLA determines CD8+ T cell repertoire shape and cross-reactive memory responses to SARS-CoV-2.
2022 · Joshua M Francis, Del Leistritz-Edwards, et al. · PubMed · 88
Design of novel FN3 domains with high stability by a consensus sequence approach
2012 · S. A. Jacobs, M. D. Diem, et al. · Protein Engineering Design and Selection · 81
Antibody modeling assessment II. Structures and models
2014 · Alexey Teplyakov, Jinquan Luo, et al. · Proteins Structure Function and Bioinformatics · 72
IgG2 Fc structure and the dynamic features of the IgG CH2–CH3 interface
2013 · Alexey Teplyakov, Yonghong Zhao, et al. · Molecular Immunology · 70
Structural diversity in a human antibody germline library
2016 · Alexey Teplyakov, Galina Obmolova, et al. · mAbs · 60
1-13C amino acid selective labeling in a 2H15N background for NMR studies of large proteins
2007 · Koh Takeuchi, Elise Ng, et al. · Journal of Biomolecular NMR · 55
Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure
2012 · Jinquan Luo, Galina Obmolova, et al. · Journal of Molecular Biology · 51
Promoting crystallization of antibody–antigen complexesviamicroseed matrix screening
2010 · Galina Obmolova, Thomas J. Malia, et al. · Acta Crystallographica Section D Biological Crystallography · 41
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Human Framework Adaptation of a Mouse Anti-Human IL-13 Antibody
2010 · Johan Fransson, Alexey Teplyakov, et al. · Journal of Molecular Biology · 41
NMR Distinction of Single- and Multiple-Mode Binding of Small-Molecule Protein Ligands
2006 · Mikhail Reibarkh, Thomas J. Malia, et al. · Journal of the American Chemical Society · 40
Anti-Tau Monoclonal Antibodies Derived from Soluble and Filamentous Tau Show Diverse Functional Properties in vitro and in vivo
2018 · Marc Vandermeeren, Marianne Borgers, et al. · Journal of Alzheimer s Disease · 39
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Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888
2012 · Galina Obmolova, Alexey Teplyakov, et al. · Molecular Immunology · 36
P1‐052: a Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Anti‐phospho‐tau Antibody Jnj‐63733657 in Healthy Subjects
2019 · Wendy R. Galpern, Marc Mercken, et al. · Alzheimer s & Dementia · 29
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Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections
2023 · Peter T. Buckley, Rita Chan, et al. · Cell Host & Microbe · 26
Protein crystallization with microseed matrix screening: application to human germline antibody Fabs
2014 · Galina Obmolova, Thomas J. Malia, et al. · Acta Crystallographica Section F Structural Biology Communications · 23
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Coevolution of Antibody Stability and Vκ CDR-L3 Canonical Structure
2010 · Jinquan Luo, Galina Obmolova, et al. · Journal of Molecular Biology · 23
Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody
2020 · Kristof Van Kolen, Thomas J. Malia, et al. · Journal of Alzheimer s Disease · 20
Structure of the EMMPRIN N‐terminal domain 1: Dimerization via β‐strand swapping
2009 · Jinquan Luo, Alexey Teplyakov, et al. · Proteins Structure Function and Bioinformatics · 20
Identification of individual protein–ligand NOEs in the limit of intermediate exchange
2006 · Mikhail Reibarkh, Thomas J. Malia, et al. · Journal of Biomolecular NMR · 20
Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge
2014 · Thomas J. Malia, Alexey Teplyakov, et al. · Proteins Structure Function and Bioinformatics · 16
Works count: 78
Citation count: 3,484
H-index: 21
I10-index: 35
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