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Author

Elizabeth A. Middleton

Observed names: E A Middleton, E. Middleton, E.A. Middleton, Elizabeth A Middleton, Elizabeth Middleton, Middleton, Elizabeth A.
Institution: University of Utah
Observed institutions: University of Iowa, Cleveland Clinic, University of Utah, Intermountain Medical Center, National Heart, Lung, and Blood Institute, Association Clinique et Thérapeutique Infantile du Val de Marne, University of Utah Health Care
ORCID: 0000-0002-5120-8202
Observed ORCID: 0000-0002-5120-8202
OpenAlex ID: A5054832337
Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome
2020 · Elizabeth A. Middleton, Xue-Yan He, et al. · Blood · 1,460
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Platelet gene expression and function in patients with COVID-19
2020 · Bhanu Kanth Manne, Frederik Denorme, et al. · Blood · 946
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Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis
2021 · Jonathan E. Sevransky, Richard E. Rothman, et al. · JAMA · 283
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Platelets in Pulmonary Immune Responses and Inflammatory Lung Diseases
2016 · Elizabeth A. Middleton, Andrew S. Weyrich, et al. · Physiological Reviews · 190
Sepsis alters the transcriptional and translational landscape of human and murine platelets
2019 · Elizabeth A. Middleton, Jesse W. Rowley, et al. · Blood · 172
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Platelet MHC class I mediates CD8+ T-cell suppression during sepsis
2021 · Li Guo, Sikui Shen, et al. · Blood · 120
Cytokine release syndrome in COVID-19: Innate immune, vascular, and platelet pathogenic factors differ in severity of disease and sex
2020 · Aaron C Petrey, Fares Qeadan, et al. · Journal of Leukocyte Biology · 111
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Deletion of GLUT1 and GLUT3 Reveals Multiple Roles for Glucose Metabolism in Platelet and Megakaryocyte Function
2017 · Trevor P. Fidler, Robert A. Campbell, et al. · Cell Reports · 89
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COVID-19 generates hyaluronan fragments that directly induce endothelial barrier dysfunction
2021 · Kimberly A. Queisser, Rebecca A. Mellema, et al. · JCI Insight · 88
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COVID‐19 patients exhibit reduced procoagulant platelet responses
2020 · Frederik Denorme, Bhanu Kanth Manne, et al. · Journal of Thrombosis and Haemostasis · 71
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Abatacept, Cenicriviroc, or Infliximab for Treatment of Adults Hospitalized With COVID-19 Pneumonia
2023 · Jane A. O’Halloran, Emily R. Ko, et al. · JAMA · 70
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Amicus or Adversary Revisited: Platelets in Acute Lung Injury and Acute Respiratory Distress Syndrome
2018 · Elizabeth A. Middleton, Matthew T. Rondina, et al. · American Journal of Respiratory Cell and Molecular Biology · 63
The Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19
2022 · ACTIV-3/TICO Study Group, Angela J. Rogers, et al. · Annals of Internal Medicine · 60
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Glucose Metabolism Is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes
2019 · Trevor P. Fidler, Alex Marti, et al. · Diabetes · 60
Comparison of the coagulopathies associated with COVID‐19 and sepsis
2021 · Robert A. Campbell, Yohei Hisada, et al. · Research and Practice in Thrombosis and Haemostasis · 57
IFITM3 regulates fibrinogen endocytosis and platelet reactivity in nonviral sepsis
2022 · Robert A. Campbell, Bhanu Kanth Manne, et al. · Journal of Clinical Investigation · 52
PDK1 governs thromboxane generation and thrombosis in platelets by regulating activation of Raf1 in the MAPK pathway
2018 · B.K. Manne, P. Münzer, et al. · Journal of Thrombosis and Haemostasis · 48
Glucose Transporter 3 Potentiates Degranulation and Is Required for Platelet Activation
2017 · Trevor P. Fidler, Elizabeth A. Middleton, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 43
Acetaminophen for Prevention and Treatment of Organ Dysfunction in Critically Ill Patients With Sepsis
2024 · Lorraine B. Ware, Lorraine B. Ware, et al. · JAMA · 42
Association of Vitamin C, Thiamine, and Hydrocortisone Infusion With Long-term Cognitive, Psychological, and Functional Outcomes in Sepsis Survivors
2023 · Shawniqua Williams Roberson, Samuel Nwosu, et al. · JAMA Network Open · 37
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Heparanase expression and activity are increased in platelets during clinical sepsis
2021 · Alicia S. Eustes, Robert A. Campbell, et al. · Journal of Thrombosis and Haemostasis · 36
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MAPK-interacting kinase 1 regulates platelet production, activation, and thrombosis
2022 · Bhanu Kanth Manne, Robert A. Campbell, et al. · Blood · 35
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Mucosal-associated invariant T (MAIT) cells mediate protective host responses in sepsis
2020 · Shubhanshi Trivedi, Daniel Labuz, et al. · eLife · 35
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Platelets in infectious disease
2016 · Elizabeth Middleton, Matthew T. Rondina · Hematology · 30
Human platelets display dysregulated sepsis-associated autophagy, induced by altered LC3 protein-protein interaction of the Vici-protein EPG5
2021 · Hansjörg Schwertz, Jesse W. Rowley, et al. · Autophagy · 28
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Works count: 78
Citation count: 4,557
H-index: 27
I10-index: 39
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