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Ole Andreas Andersen

Observed names: O.A. Andersen, Ole A Andersen, Ole A. Andersen, Ole Andersen, Ole A. Andersen
ORCID: 0000-0002-0408-645X
Observed ORCID: 0000-0002-0408-645X
OpenAlex ID: A5055079299
Methylxanthine Drugs Are Chitinase Inhibitors: Investigation of Inhibition and Binding Modes
2005 · Francesco V. Rao, Ole A. Andersen, et al. · Chemistry & Biology · 122
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Crystal Structure of the Ternary Complex of the Catalytic Domain of Human Phenylalanine Hydroxylase with Tetrahydrobiopterin and 3-(2-Thienyl)-l-alanine, and its Implications for the Mechanism of Catalysis and Substrate Activation
2002 · Ole Andreas Andersen, Torgeir Flatmark, et al. · Journal of Molecular Biology · 114
High resolution crystal structures of the catalytic domain of human phenylalanine hydroxylase in its catalytically active Fe(II) form and binary complex with tetrahydrobiopterin
2001 · Ole Andreas Andersen, Torgeir Flatmark, et al. · Journal of Molecular Biology · 108
Trypsin specificity as elucidated by LIE calculations, X‐ray structures, and association constant measurements
2004 · Hanna‐Kirsti Schrøder Leiros, Bjørn Olav Brandsdal, et al. · Protein Science · 96
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2.0Å Resolution Crystal Structures of the Ternary Complexes of Human Phenylalanine Hydroxylase Catalytic Domain with Tetrahydrobiopterin and 3-(2-Thienyl)-l-alanine or l-Norleucine: Substrate Specificity and Molecular Motions Related to Substrate Binding
2003 · Ole Andreas Andersen, Anne J Stokka, et al. · Journal of Molecular Biology · 96
Natural product family 18 chitinase inhibitors
2005 · Ole A. Andersen, Mark J. Dixon, et al. · Natural Product Reports · 84
Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB
2016 · Michael F. Mesleh, Jason B. Cross, et al. · Bioorganic & Medicinal Chemistry Letters · 73
Discovery and Structure–Activity Relationship of Potent and Selective Covalent Inhibitors of Transglutaminase 2 for Huntington’s Disease
2012 · Michael E. Prime, Ole A. Andersen, et al. · Journal of Medicinal Chemistry · 70
Structure-Based Dissection of the Natural Product Cyclopentapeptide Chitinase Inhibitor Argifin
2008 · Ole A. Andersen, Amit Nathubhai, et al. · Chemistry & Biology · 68
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The multiple roles of computational chemistry in fragment-based drug design
2009 · Richard Law, Oliver Barker, et al. · Journal of Computer-Aided Molecular Design · 60
Screening-based Discovery and Structural Dissection of a Novel Family 18 Chitinase Inhibitor
2006 · Alexander W. Schüttelkopf, Ole A. Andersen, et al. · Journal of Biological Chemistry · 57
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Crystal Structure of Alkaline Phosphatase from the Antarctic Bacterium TAB5
2006 · Ellen Wang, Dimitris Koutsioulis, et al. · Journal of Molecular Biology · 50
Analyzing Airway Inflammation with Chemical Biology: Dissection of Acidic Mammalian Chitinase Function with a Selective Drug-like Inhibitor
2011 · Tara E. Sutherland, Ole A. Andersen, et al. · Chemistry & Biology · 48
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Discovery of Pyrazolopyridones as a Novel Class of Gyrase B Inhibitors Using Structure Guided Design
2016 · Jason B. Cross, Jing Zhang, et al. · ACS Medicinal Chemistry Letters · 46
Structural basis for enzymatic excision of N1‐methyladenine and N3‐methylcytosine from DNA
2007 · Ingar Leiros, Marivi P Nabong, et al. · The EMBO Journal · 43
An efficient synthesis of argifin: A natural product chitinase inhibitor with chemotherapeutic potential
2005 · Mark J. Dixon, Ole A. Andersen, et al. · Bioorganic & Medicinal Chemistry Letters · 42
Solid-phase synthesis of cyclic peptide chitinase inhibitors: SAR of the argifin scaffold
2008 · Mark J. Dixon, Amit Nathubhai, et al. · Organic & Biomolecular Chemistry · 35
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High-resolution structures of three new trypsin–squash-inhibitor complexes: a detailed comparison with other trypsins and their complexes
1999 · Ronny Helland, Gunnar I. Berglund, et al. · Acta Crystallographica Section D Biological Crystallography · 35
Cross-linking of protein crystals as an aid in the generation of binary protein–ligand crystal complexes, exemplified by the human PDE10a–papaverine structure
2009 · Ole Andreas Andersen, Dorian Leo Schönfeld, et al. · Acta Crystallographica Section D Biological Crystallography · 29
Bisdionin C—A Rationally Designed, Submicromolar Inhibitor of Family 18 Chitinases
2011 · Alexander W. Schüttelkopf, Ole A. Andersen, et al. · ACS Medicinal Chemistry Letters · 25
First Synthesis of Argadin: A Nanomolar Inhibitor of Family‐18 Chitinases
2006 · Mark J. Dixon, Ole A. Andersen, et al. · European Journal of Organic Chemistry · 25
Studies on the regulatory properties of the pterin cofactor and dopamine bound at the active site of human phenylalanine hydroxylase
2003 · Therese Solstad, Anne J. Stokka, et al. · European Journal of Biochemistry · 25
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Structure-based discovery of LpxC inhibitors
2017 · Jing Zhang, Audrey Chan, et al. · Bioorganic & Medicinal Chemistry Letters · 24
Discovery of Novel UDP- N -Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa
2021 · M. Dominic Ryan, Alastair L. Parkes, et al. · Journal of Medicinal Chemistry · 23
Deamidation of labile asparagine residues in the autoregulatory sequence of human phenylalanine hydroxylase
2003 · Therese Solstad, Raquel N. Carvalho, et al. · European Journal of Biochemistry · 20
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Works count: 59
Citation count: 1,430
H-index: 23
I10-index: 25
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