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Author

Alexander Kleger

Observed names: A Kleger, A. Kleger, Kleger, A., Kleger, Alexander
Observed institutions: University of Bonn, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universität Ulm, Justus-Liebig-Universität Gießen, Universitätsmedizin Greifswald, LMU Klinikum, Universität Greifswald, Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung (IPK), Jena University Hospital, University Hospital Ulm, University Hospital Carl Gustav Carus, Center for Regenerative Therapies Dresden, Martin Luther University Halle-Wittenberg, Friedrich Schiller University Jena, Technische Universität Dresden, Ludwig-Maximilians-Universität München, RWTH Aachen University, Ruhr University Bochum, KU Leuven
ORCID: 0000-0003-0592-5232
Observed ORCID: 0000-0003-0592-5232
OpenAlex ID: A5055082801
SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies
2021 · Markus Hoffmann, Prerna Arora, et al. · Cell · 941
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SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas
2021 · Janis A. Müller, Rüdiger Groß, et al. · Nature Metabolism · 553
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Interpreting type 1 diabetes risk with genetics and single-cell epigenomics
2021 · Joshua Chiou, Ryan J. Geusz, et al. · Nature · 459
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Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling
2016 · Meike Hohwieler, Anett Illing, et al. · Gut · 210
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DNA damage repair as a target in pancreatic cancer: state-of-the-art and future perspectives
2020 · Lukas Perkhofer, Johann Gout, et al. · Gut · 206
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IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro
2021 · Caterina Prelli Bozzo, Rayhane Nchioua, et al. · Nature Communications · 185
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Telomerase gene mutations are associated with cirrhosis formation
2011 · Daniel Hartmann, Ujala Srivastava, et al. · Hepatology · 176
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Perioperative or only adjuvant gemcitabine plus nab-paclitaxel for resectable pancreatic cancer (NEONAX)—a randomized phase II trial of the AIO pancreatic cancer group
2022 · T. Seufferlein, W. Uhl, et al. · Annals of Oncology · 169
Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection
2021 · Lukas Wettstein, Tatjana Weil, et al. · Nature Communications · 128
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PDX-derived organoids model in vivo drug response and secrete biomarkers
2020 · Ling Huang, Bruno Bockorny, et al. · JCI Insight · 128
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Loss of ATM accelerates pancreatic cancer formation and epithelial–mesenchymal transition
2015 · Ronan Russell, Lukas Perkhofer, et al. · Nature Communications · 126
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Genotyping of circulating tumor DNA in cholangiocarcinoma reveals diagnostic and prognostic information
2019 · T. J. Ettrich, D. Schwerdel, et al. · Scientific Reports · 117
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ATM Deficiency Generating Genomic Instability Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Therapy-Induced DNA Damage
2017 · Lukas Perkhofer, Anna Schmitt, et al. · Cancer Research · 112
Modulation of Calcium-Activated Potassium Channels Induces Cardiogenesis of Pluripotent Stem Cells and Enrichment of Pacemaker-Like Cells
2010 · Alexander Kleger, Thomas Seufferlein, et al. · Circulation · 112
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Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells
2021 · Markus Breunig, Jessica Merkle, et al. · Cell stem cell · 110
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Drug Inhibition of SARS-CoV-2 Replication in Human Pluripotent Stem Cell–Derived Intestinal Organoids
2020 · Jana Krüger, Rüdiger Groß, et al. · Cellular and Molecular Gastroenterology and Hepatology · 102
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Single-cell-resolved differentiation of human induced pluripotent stem cells into pancreatic duct-like organoids on a microwell chip
2021 · Sandra Wiedenmann, Markus Breunig, et al. · Nature Biomedical Engineering · 97
Detection of Hot-Spot Mutations in Circulating Cell-Free DNA From Patients With Intraductal Papillary Mucinous Neoplasms of the Pancreas
2016 · Andreas W. Berger, Daniel Schwerdel, et al. · Gastroenterology · 93
The role of pluripotency factors to drive stemness in gastrointestinal cancer
2016 · Martin Müller, Patrick C. Hermann, et al. · Stem Cell Research · 92
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Evidence of SARS-CoV2 Entry Protein ACE2 in the Human Nose and Olfactory Bulb
2020 · M. Klingenstein, S. Klingenstein, et al. · Cells Tissues Organs · 91
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Pancreatic cancer‐derived organoids – a disease modeling tool to predict drug response
2020 · Pierre‐Olivier Frappart, Karolin Walter, et al. · United European Gastroenterology Journal · 84
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Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer
2020 · Johann Gout, Lukas Perkhofer, et al. · Gut · 81
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TBX3 Directs Cell-Fate Decision toward Mesendoderm
2013 · Clair E. Weidgang, Ronan Russell, et al. · Stem Cell Reports · 77
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Smarter drugs emerging in pancreatic cancer therapy
2014 · A. Kleger, L. Perkhofer, et al. · Annals of Oncology · 76
Human stem cell-based retina on chip as new translational model for validation of AAV retinal gene therapy vectors
2021 · Kevin Achberger, Madalena Cipriano, et al. · Stem Cell Reports · 74
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Works count: 386
Citation count: 7,485
H-index: 43
I10-index: 112
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