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Spencer C. Peck

Observed names: S. C. Peck, SPENCER C. PECK, Spencer C Peck, Spencer C. Peck
ORCID: 0000-0002-1599-6635
Observed ORCID: 0000-0002-1599-6635
OpenAlex ID: A5056317331
A glycyl radical enzyme enables hydrogen sulfide production by the human intestinal bacterium Bilophila wadsworthia
2019 · Spencer C. Peck, Karin Denger, et al. · Proceedings of the National Academy of Sciences · 191
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A prominent glycyl radical enzyme in human gut microbiomes metabolizes trans -4-hydroxy- l -proline
2017 · B. J. Levin, Y. Y. Huang, et al. · Science · 142
Evidence that the Fosfomycin-Producing Epoxidase, HppE, Is a Non–Heme-Iron Peroxidase
2013 · Chen Wang, Wei-chen Chang, et al. · Science · 78
Phosphonate biosynthesis and catabolism: a treasure trove of unusual enzymology
2013 · Spencer C Peck, Wilfred A van der Donk · Current Opinion in Chemical Biology · 75
Structural basis for methylphosphonate biosynthesis
2017 · David A. Born, Emily C. Ulrich, et al. · Science · 56
Go it alone: four-electron oxidations by mononuclear non-heme iron enzymes
2016 · Spencer C. Peck, Wilfred A. van der Donk · JBIC Journal of Biological Inorganic Chemistry · 45
Oxygen-18 Kinetic Isotope Effects of Nonheme Iron Enzymes HEPD and MPnS Support Iron(III) Superoxide as the Hydrogen Abstraction Species
2015 · Hui Zhu, Spencer C. Peck, et al. · Journal of the American Chemical Society · 44
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O–H Activation by an Unexpected Ferryl Intermediate during Catalysis by 2-Hydroxyethylphosphonate Dioxygenase
2017 · Spencer C. Peck, Chen Wang, et al. · Journal of the American Chemical Society · 39
On the Stereochemistry of 2-Hydroxyethylphosphonate Dioxygenase
2011 · John T. Whitteck, Petra Malova, et al. · Journal of the American Chemical Society · 38
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Structure and Function of Phosphonoacetaldehyde Dehydrogenase: The Missing Link in Phosphonoacetate Formation
2013 · Vinayak Agarwal, Spencer C. Peck, et al. · Chemistry & Biology · 29
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Discovery and Biosynthesis of Phosphonate and Phosphinate Natural Products
2012 · Spencer C. Peck, Jiangtao Gao, et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 28
Mechanistic Investigation of Methylphosphonate Synthase, a Non-Heme Iron-Dependent Oxygenase
2012 · Heather A. Cooke, Spencer C. Peck, et al. · Journal of the American Chemical Society · 27
Mechanism and Substrate Recognition of 2-Hydroxyethylphosphonate Dioxygenase
2011 · Spencer C. Peck, Heather A. Cooke, et al. · Biochemistry · 26
A Common Late-Stage Intermediate in Catalysis by 2-Hydroxyethyl-phosphonate Dioxygenase and Methylphosphonate Synthase
2015 · Spencer C. Peck, Jonathan R. Chekan, et al. · Journal of the American Chemical Society · 24
Use of the dehydrophos biosynthetic enzymes to prepare antimicrobial analogs of alaphosphin
2018 · Despina J. Bougioukou, Chi P. Ting, et al. · Organic & Biomolecular Chemistry · 8
Stereochemistry of hydride transfer by group III alcohol dehydrogenases involved in phosphonate biosynthesis
2012 · Spencer C. Peck, Seung Young Kim, et al. · MedChemComm · 7
Discovery of Pyrazolopyrazines as Selective, Potent, and Mutant-Active MET Inhibitors with Intracranial Efficacy
2024 · Quinn A. Bumpers, Robert W. Pipal, et al. · Journal of Medicinal Chemistry · 5
Positive and radical
2013 · Spencer C. Peck, Wilfred A. van der Donk · Nature · 1
3065-LB: Nonclinical Profile of AMB-702, a Potent and Novel Oral GLP-1 Receptor Agonist
2026 · PATRICE A. LEE, KARIN D. BROWN, et al. · Diabetes
Mechanistic investigations of enzymes in phosphonate metabolism
2015 · Spencer C. Peck · Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)
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Works count: 22
Citation count: 863
H-index: 14
I10-index: 14
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