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Natalie J. Spillman

Observed names: NATALIE SPILLMAN, Natalie J Spillman, Natalie Jane Spillman, Natalie Spillman, Natalie J. Spillman, Spillman, Natalie Jane
Observed institutions: Australian National University, Howard Hughes Medical Institute, Harvard University, The University of Melbourne, Washington University in St. Louis, National Health and Medical Research Council
ORCID: 0000-0002-3454-1636
Observed ORCID: 0000-0002-3454-1636
OpenAlex ID: A5057005686
Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome
2018 · Jessica L. Bridgford, Stanley C. Xie, et al. · Nature Communications · 308
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Na+ Regulation in the Malaria Parasite Plasmodium falciparum Involves the Cation ATPase PfATP4 and Is a Target of the Spiroindolone Antimalarials
2013 · Natalie J. Spillman, Richard J.W. Allen, et al. · Cell Host & Microbe · 257
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(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium
2014 · María Belén Jiménez-Díaz, Daniel Ebert, et al. · Proceedings of the National Academy of Sciences · 256
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Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum
2014 · Akhil B. Vaidya, Joanne M. Morrisey, et al. · Nature Communications · 137
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The malaria parasite cation ATPase PfATP4 and its role in the mechanism of action of a new arsenal of antimalarial drugs
2015 · Natalie Jane Spillman, Kiaran Kirk · International Journal for Parasitology Drugs and Drug Resistance · 125
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Protein Export into Malaria Parasite–Infected Erythrocytes: Mechanisms and Functional Consequences
2015 · Natalie J. Spillman, Josh R. Beck, et al. · Annual Review of Biochemistry · 118
Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking
2019 · Kit Kennedy, Simon A. Cobbold, et al. · PLoS Biology · 112
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Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box
2021 · Janette Reader, Mariëtte E. van der Watt, et al. · Nature Communications · 97
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Target Validation and Identification of Novel Boronate Inhibitors of the Plasmodium falciparum Proteasome
2018 · Stanley C. Xie, David L. Gillett, et al. · Journal of Medicinal Chemistry · 71
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The chaperonin TRiC forms an oligomeric complex in the malaria parasite cytosol
2017 · Natalie J. Spillman, Josh R. Beck, et al. · Cellular Microbiology · 62
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The structure of the PA28–20S proteasome complex from Plasmodium falciparum and implications for proteostasis
2019 · Stanley C. Xie, Riley D. Metcalfe, et al. · Nature Microbiology · 44
Acid extrusion from the intraerythrocytic malaria parasite is not via a Na+/H+ exchanger
2008 · Natalie J. Spillman, Richard J.W. Allen, et al. · Molecular and Biochemical Parasitology · 39
Na+ extrusion imposes an acid load on the intraerythrocytic malaria parasite
2013 · Natalie J. Spillman, Richard J.W. Allen, et al. · Molecular and Biochemical Parasitology · 32
Exported Epoxide Hydrolases Modulate Erythrocyte Vasoactive Lipids during Plasmodium falciparum Infection
2016 · Natalie J. Spillman, Varun K. Dalmia, et al. · mBio · 30
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Violacein-Induced Chaperone System Collapse Underlies Multistage Antiplasmodial Activity
2021 · Tatyana Almeida Tavella, Noeli Soares Melo da Silva, et al. · ACS Infectious Diseases · 18
A single point mutation in the Plasmodium falciparum FtsH1 metalloprotease confers actinonin resistance
2020 · Christopher D Goodman, Taher Uddin, et al. · eLife · 11
Author response: A single point mutation in the Plasmodium falciparum FtsH1 metalloprotease confers actinonin resistance
2020 · Christopher D Goodman, Taher Uddin, et al. · eLife · 1
pH Regulation
2013 · Natalie Jane Spillman, Leann Tilley · Springer eBooks · 1
Na⁺ regulation in the intraerythrocytic malaria parasite
2011 · Spillman, Natalie Jane · ANU Open Research (Australian National University) · 1
Na+-dependent acid efflux from P. falciparum: PfNHE or residual nigericin?
2009 · Natalie J. Spillman, Richard J.W. Allen, et al. · Molecular and Biochemical Parasitology · 1
pH Regulation
2025 · Natalie Jane Spillman, Leann Tilley · Springer eBooks
The structure of the Plasmodium falciparum 20S proteasome in complex with the PA28 activator
2019 · Riley D. Metcalfe, Stanley C. Xie, et al. · Acta Crystallographica Section A Foundations and Advances
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Cryo-em of the Malaria Parasite Pa28/20s Proteasome Complex Reveals an Unusual Activation Mechanism With Implications for Artemisinin Sensitivity
2019 · Stanley C. Xie, Michael D. W. Griffin, et al. · Protein Science
Reply to “Misclassification of PfEH1 and PfEH2 as Epoxide Hydrolases”
2017 · Daniel E. Goldberg, Natalie J. Spillman · mBio
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pH regulation in P. falciparum
2013 · Natalie J. Spillman, Leann Tilley
Works count: 27
Citation count: 1,721
H-index: 15
I10-index: 16
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