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Pavla Perlíková

Observed names: Pavla Perlikova, Pavla Perlíková, Pavla Spáčilová, Perlikova, Pavla, Perlíková, P. (Pavla), Perlíková, Pavla
ORCID: 0000-0002-8500-0493
Observed ORCID: 0000-0002-8500-0493
OpenAlex ID: A5057286176
Pyrrolo[2,3‐ d ]pyrimidine (7‐deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides
2017 · Pavla Perlíková, Michal Hocek · Medicinal Research Reviews · 123
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Synthesis and Significant Cytostatic Activity of 7-Hetaryl-7-deazaadenosines
2011 · Aurelie Bourderioux, Petr Nauš, et al. · Journal of Medicinal Chemistry · 112
Synthesis, Cytostatic, Antimicrobial, and Anti-HCV Activity of 6-Substituted 7-(Het)aryl-7-deazapurine Ribonucleosides
2014 · Petr Nauš, Olga Caletková, et al. · Journal of Medicinal Chemistry · 71
2‐Substituted dATP Derivatives as Building Blocks for Polymerase‐Catalyzed Synthesis of DNA Modified in the Minor Groove
2016 · Ján Matyašovský, Pavla Perlíková, et al. · Angewandte Chemie International Edition · 60
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Enzymatic synthesis of base-modified RNA by T7 RNA polymerase. A systematic study and comparison of 5-substituted pyrimidine and 7-substituted 7-deazapurine nucleoside triphosphates as substrates
2018 · Nemanja Milisavljevič, Pavla Perlíková, et al. · Organic & Biomolecular Chemistry · 49
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Inhibition of non-templated nucleotide addition by DNA polymerases in primer extension using twisted intercalating nucleic acid modified templates
2015 · Pedro Güixens-Gallardo, Michal Hocek, et al. · Bioorganic & Medicinal Chemistry Letters · 32
Cyclo Sal‐phosphate Pronucleotides of Cytostatic 6‐(Het)aryl‐7‐deazapurine Ribonucleosides: Synthesis, Cytostatic Activity, and Inhibition of Adenosine Kinases
2010 · Pavla Spáčilová, Petr Nauš, et al. · ChemMedChem · 31
Polymerase Synthesis and Restriction Enzyme Cleavage of DNA Containing 7‐Substituted 7‐Deazaguanine Nucleobases
2015 · Michaela Mačková, Soňa Boháčová, et al. · ChemBioChem · 30
Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2′-C-methylribonucleosides, 2′-deoxy-2′-fluoroarabinonucleosides, arabinonucleosides and 2′-deoxyribonucleosides
2012 · Petr Nauš, Pavla Perlíková, et al. · Bioorganic & Medicinal Chemistry · 30
7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action
2016 · Pavla Perlíková, Gabriela Rylová, et al. · Molecular Cancer Therapeutics · 29
Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides
2018 · Anna Tokarenko, Barbora Lišková, et al. · Journal of Medicinal Chemistry · 28
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Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists
2022 · Zdeněk Vavřina, Pavla Perlíková, et al. · Journal of Medicinal Chemistry · 26
Phosphoramidate pronucleotides of cytostatic 6-aryl-7-deazapurine ribonucleosides
2010 · Pavla Perlíková, Radek Pohl, et al. · Bioorganic & Medicinal Chemistry · 26
Unlocked Nucleic Acids with a Pyrene‐Modified Uracil: Synthesis, Hybridization Studies, Fluorescent Properties and i‐Motif Stability
2013 · Pavla Perlíková, Kasper K. Karlsen, et al. · ChemBioChem · 24
2‐Substituted dATP Derivatives as Building Blocks for Polymerase‐Catalyzed Synthesis of DNA Modified in the Minor Groove
2016 · Ján Matyašovský, Pavla Perlíková, et al. · Angewandte Chemie · 21
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Influence of major-groove chemical modifications of DNA on transcription by bacterial RNA polymerases
2016 · Veronika Raindlová, Martina Janoušková, et al. · Nucleic Acids Research · 20
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Synthesis and Cytostatic and Antiviral Activities of 2′‐Deoxy‐2′,2′‐difluororibo‐ and 2′‐Deoxy‐2′‐fluororibonucleosides Derived from 7‐(Het)aryl‐7‐deazaadenines
2013 · Pavla Perlíková, Ludovic Eberlin, et al. · ChemMedChem · 18
6-Alkyl-, 6-aryl- or 6-hetaryl-7-deazapurine ribonucleosides as inhibitors of human or MTB adenosine kinase and potential antimycobacterial agents
2013 · Pavla Perlíková, Petr Konečný, et al. · MedChemComm · 18
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Synthesis and Cytotoxic and Antiviral Activity Profiling of All‐Four Isomeric Series of Pyrido‐Fused 7‐Deazapurine Ribonucleosides
2020 · Lucia Veselovská, Natálie Kudlová, et al. · Chemistry - A European Journal · 17
Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides
2015 · Petr Nauš, Olga Caletková, et al. · Bioorganic & Medicinal Chemistry · 17
Sugar-modified derivatives of cytostatic 6-(het)aryl-7-deazapurine nucleosides: 2′-C-methylribonucleosides, arabinonucleosides and 2′-deoxy-2′-fluoroarabinonucleosides
2011 · Petr Nauš, Pavla Perlíková, et al. · Collection of Czechoslovak Chemical Communications · 16
Synthesis of 2′-deoxy-2′-fluororibo- and 2′-deoxy-2′,2′-difluororibonucleosides derived from 6-(het)aryl-7-deazapurines
2012 · Pavla Perlíková, Neus Jornet Martínez, et al. · Tetrahedron · 14
Isomeric Naphtho‐Fused 7‐Deazapurine Nucleosides and Nucleotides: Synthesis, Biological Activity, Photophysical Properties and Enzymatic Incorporation to Nucleic Acids
2018 · Ketaki Ghosh, Pavla Perlíková, et al. · European Journal of Organic Chemistry · 13
2-Deoxyglycoside Conjugates of Lupane Triterpenoids with High Cytotoxic Activity—Synthesis, Activity, and Pharmacokinetic Profile
2019 · Pavla Perlikova, Miroslav Kvasnica, et al. · Bioconjugate Chemistry · 12
Synthesis and migrastatic activity of cytochalasin analogues lacking a macrocyclic moiety
2023 · Bedřich Formánek, Dorian Dupommier, et al. · RSC Medicinal Chemistry · 10
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Works count: 64
Citation count: 882
H-index: 18
I10-index: 25
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