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Ann-Sofie Sandinge

Observed names: A. Sandinge, A.‐S. Sandinge
ORCID: 0000-0002-1322-2580
Observed ORCID: 0000-0002-1322-2580
OpenAlex ID: A5058949331
Structural and functional characterization of a specific antidote for ticagrelor
2015 · Andrew Buchanan, Philip Newton, et al. · Blood · 93
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Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein
2021 · Nigel Davies, Daniel Hovdal, et al. · Molecular Therapy — Nucleic Acids · 86
Ancestral Sequence Reconstruction of a Cytochrome P450 Family Involved in Chemical Defense Reveals the Functional Evolution of a Promiscuous, Xenobiotic-Metabolizing Enzyme in Vertebrates
2022 · Kurt L. Harris, Raine E.S. Thomson, et al. · Molecular Biology and Evolution · 35
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Hemostatic effects of the ticagrelor antidote MEDI2452 in pigs treated with ticagrelor on a background of aspirin
2017 · S. Pehrsson, K. J Johansson, et al. · Journal of Thrombosis and Haemostasis · 27
Application of Accelerator Mass Spectrometry to Characterize the Mass Balance Recovery and Disposition of AZD4831, a Novel Myeloperoxidase Inhibitor, following Administration of an Oral Radiolabeled Microtracer Dose in Humans
2023 · Chandrali Bhattacharya, Ann-Sofie Sandinge, et al. · Drug Metabolism and Disposition · 13
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Biotransformation of the Novel Myeloperoxidase Inhibitor AZD4831 in Preclinical Species and Humans
2023 · Ulrik Jurva, Lars Weidolf, et al. · Drug Metabolism and Disposition · 12
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Inhibition of SGLT2 Preserves Function and Promotes Proliferation of Human Islets Cells In Vivo in Diabetic Mice
2022 · Daniel Karlsson, Andrea Ahnmark, et al. · Biomedicines · 11
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Developing an injectable co-formulation of two antidiabetic drugs: Excipient impact on peptide aggregation and pharmacokinetic properties
2020 · Anne-Laure Lainé, Sophie Houvenagel, et al. · International Journal of Pharmaceutics · 11
Quantification of unbound concentration of ticagrelor in plasma as a proof of mechanism biomarker of the reversal agent, MEDI2452
2018 · Ann-Sofie Sandinge, Annika Janefeldt, et al. · PLoS ONE · 7
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Biocatalysis using Thermostable Cytochrome P450 Enzymes in Bacterial Membranes – Comparison of Metabolic Pathways with Human Liver Microsomes and Recombinant Human Enzymes
2024 · Ulrik Jurva, Ann-Sofie Sandinge, et al. · Drug Metabolism and Disposition · 4
A Specific Antidote for Ticagrelor
2015 · Sven Nylander, Susanne Pehrsson, et al. · Journal of the American College of Cardiology · 2
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Ticagrelor antidote candidate Fab 72 in complex with ticagrelor
2015 · A. Buchanan, P. Newton, et al. · Worldwide Protein Data Bank
Works count: 12
Citation count: 301
H-index: 8
I10-index: 8
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