Author

Gloria López‐Castejón

Observed names: G Lopez-Castejn, G Lopez-Castejon, G. Lopez-Castejon, G. López-Castejón, Gloria Lopez-Castejon, Gloria Lopez-Castejón, Gloria Lopez‐Castejon, Gloria López Castejón, Gloria López-Castejón, Lopez-Castejon Gloria, Lopez-Castejon, Gloria

Institutions: Manchester Academic Health Science Centre, University of Manchester

Observed institutions: Manchester Academic Health Science Centre, University of Manchester, Manchester Collaborative Centre for Inflammation Research, Universidad de Murcia, Leipzig University

ORCID: 0000-0002-8585-3381

Observed ORCID: 0000-0002-8585-3381

OpenAlex ID: A5059071069

Understanding the mechanism of IL-1β secretion

2011 · Gloria Lopez-Castejon, David Brough · Cytokine & Growth Factor Reviews · 1,510

Cell Volume Regulation Modulates NLRP3 Inflammasome Activation

2012 · Vincent Compan, Alberto Baroja-Mazo, et al. · Immunity · 392

Nanoparticles can cause DNA damage across a cellular barrier

2009 · Gevdeep Bhabra, Aman Sood, et al. · Nature Nanotechnology · 383

Caspase-1: is IL-1 just the tip of the ICEberg?

2012 · A Denes, G Lopez-Castejon, et al. · Cell Death and Disease · 265

Canonical and Non-Canonical Activation of NLRP3 Inflammasome at the Crossroad between Immune Tolerance and Intestinal Inflammation

2017 · Carolina Pellegrini, Luca Antonioli, et al. · Frontiers in Immunology · 211

NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury

2012 · Catherine Diane Savage, Gloria Lopez-Castejon, et al. · Frontiers in Immunology · 197

Chloride regulates dynamic NLRP3-dependent ASC oligomerization and inflammasome priming

2018 · Jack P. Green, Shi Yu, et al. · Proceedings of the National Academy of Sciences · 190

The NLRP3–inflammasome as a sensor of organelle dysfunction

2020 · Paula I. Seoane, Bali Lee, et al. · The Journal of Cell Biology · 188

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation

2018 · Pablo Palazón‐Riquelme, Jonathan D Worboys, et al. · EMBO Reports · 188

Deubiquitinases Regulate the Activity of Caspase-1 and Interleukin-1β Secretion via Assembly of the Inflammasome

2012 · Gloria Lopez-Castejon, Nadia M. Luheshi, et al. · Journal of Biological Chemistry · 168

Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease

2017 · Mattia Cocco, Carolina Pellegrini, et al. · Journal of Medicinal Chemistry · 165

Microglia and macrophages differentially modulate cell death after brain injury caused by oxygen‐glucose deprivation in organotypic brain slices

2013 · Sylvie Girard, David Brough, et al. · Glia · 161

Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro

2020 · Anna Gritsenko, Shi Yu, et al. · Frontiers in Immunology · 154

Control of the inflammasome by the ubiquitin system

2019 · Gloria Lopez‐Castejon · FEBS Journal · 142

Mechanisms of NLRP3 priming in inflammaging and age related diseases

2020 · Anna Gritsenko, Jack P. Green, et al. · Cytokine & Growth Factor Reviews · 136

Interleukin-1α expression precedes IL-1β after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues

2011 · Nadia M Luheshi, Krisztina J Kovács, et al. · Journal of Neuroinflammation · 136

The activation of gilthead seabream professional phagocytes by different PAMPs underlines the behavioural diversity of the main innate immune cells of bony fish

2006 · M. Pilar Sepulcre, Gloria López-Castejón, et al. · Molecular Immunology · 135

P2X7 Receptor-Mediated Release of Cathepsins from Macrophages Is a Cytokine-Independent Mechanism Potentially Involved in Joint Diseases

2010 · Gloria Lopez-Castejon, Jill Theaker, et al. · The Journal of Immunology · 126

Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness

2011 · A. Sood, S. Salih, et al. · Nature Nanotechnology · 122

Apoptosis-Associated Speck-like Protein Containing a CARD Forms Specks but Does Not Activate Caspase-1 in the Absence of NLRP3 during Macrophage Swelling

2015 · Vincent Compan, Fátima Martín-Sánchez, et al. · The Journal of Immunology · 110

Zinc depletion regulates the processing and secretion of IL-1β

2014 · H Summersgill, H England, et al. · Cell Death and Disease · 108

Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation

2019 · Channabasavaiah B. Gurumurthy, Aidan R. O’Brien, et al. · Genome biology · 102

The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes

2019 · Victor S. Tapia, Michael J.D. Daniels, et al. · Journal of Biological Chemistry · 94

Evolution of inflammasome functions in vertebrates: Inflammasome and caspase-1 trigger fish macrophage cell death but are dispensable for the processing of IL-1β

2012 · Diego Angosto, Gloria López-Castejón, et al. · Innate Immunity · 91

Sphingosine regulates the NLRP3‐inflammasome and IL‐1β release from macrophages

2011 · Nadia M. Luheshi, James A. Giles, et al. · European Journal of Immunology · 91

Works count: 86

Citation count: 6,829

H-index: 40

I10-index: 51