Author

Nikolai Klena

Observed names: Klena N, Klena, Nikolai, N. Klena, N. T. Klena, NT Klena, Nikolai T Klena, Nikolai T. Klena, Nikolai Thomas Klena, Nikolai T. Klena, Nikolas Klena

Institution: Human Technopole

Observed institutions: University of Geneva, University of California, Los Angeles, University of Pittsburgh, Great Ormond Street Hospital, Great Ormond Street Hospital for Children NHS Foundation Trust, Centre Hospitalier Universitaire de Grenoble, Yale University, Human Technopole, Juniata College, University of Bayreuth

ORCID: 0000-0002-2631-2294

Observed ORCID: 0000-0002-2631-2294

OpenAlex ID: A5064888394

Global genetic analysis in mice unveils central role for cilia in congenital heart disease

2015 · You Li, Nikolai T. Klena, et al. · Nature · 432

DYX1C1 is required for axonemal dynein assembly and ciliary motility

2013 · UK10K, Aarti Tarkar, et al. · Nature Genetics · 279

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The complex genetics of hypoplastic left heart syndrome

2017 · Xiaoqin Liu, Hisato Yagi, et al. · Nature Genetics · 224

CCDC151 Mutations Cause Primary Ciliary Dyskinesia by Disruption of the Outer Dynein Arm Docking Complex Formation

2014 · Rim Hjeij, Alexandros Onoufriadis, et al. · The American Journal of Human Genetics · 173

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A helical inner scaffold provides a structural basis for centriole cohesion

2020 · Maeva Le Guennec, Nikolai Klena, et al. · Science Advances · 165

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Discovery of four recessive developmental disorders using probabilistic genotype and phenotype matching among 4,125 families

2015 · the DDD study, Nadia Akawi, et al. · Nature Genetics · 155

Structural Biology of Cilia and Intraflagellar Transport

2022 · Nikolai Klena, Gaia Pigino · Annual Review of Cell and Developmental Biology · 138

In situ architecture of the ciliary base reveals the stepwise assembly of intraflagellar transport trains

2022 · Hugo van den Hoek, Nikolai Klena, et al. · Science · 137

Overview of the centriole architecture

2020 · Maeva LeGuennec, Nikolai Klena, et al. · Current Opinion in Structural Biology · 111

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Visualizing the native cellular organization by coupling cryofixation with expansion microscopy (Cryo-ExM)

2022 · Marine H. Laporte, Nikolai Klena, et al. · Nature Methods · 109

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MMP21 is mutated in human heterotaxy and is required for normal left-right asymmetry in vertebrates

2015 · Anne Guimier, George C Gabriel, et al. · Nature Genetics · 95

Genetic link between renal birth defects and congenital heart disease

2016 · Jovenal T. San Agustin, Nikolai Klena, et al. · Nature Communications · 82

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Cilia and Ciliopathies in Congenital Heart Disease

2017 · Nikolai T. Klena, Brian C. Gibbs, et al. · Cold Spring Harbor Perspectives in Biology · 75

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Architecture of the centriole cartwheel‐containing region revealed by cryo‐electron tomography

2020 · Nikolai Klena, Maeva Le Guennec, et al. · The EMBO Journal · 65

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Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

2018 · Bram P. Prins, Timothy J. Mead, et al. · Genome biology · 62

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Serialized on-grid lift-in sectioning for tomography (SOLIST) enables a biopsy at the nanoscale

2024 · Ho Thuy Dung Nguyen, Gaia Perone, et al. · Nature Methods · 61

ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning

2015 · Peter G. Czarnecki, George C. Gabriel, et al. · Nature Communications · 54

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Cyclic Di-GMP Phosphodiesterases RmdA and RmdB Are Involved in Regulating Colony Morphology and Development in Streptomyces coelicolor

2012 · T. D. Hull, M.-H. Ryu, et al. · Journal of Bacteriology · 43

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Assessment of ciliary phenotype in primary ciliary dyskinesia by micro-optical coherence tomography

2017 · George M. Solomon, Richard Francis, et al. · JCI Insight · 41

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Respiratory motile cilia dysfunction in a patient with cranioectodermal dysplasia

2015 · You Li, Andrea S. Garrod, et al. · American Journal of Medical Genetics Part A · 40

Structure, interaction and nervous connectivity of beta cell primary cilia

2024 · Andreas Müller, Nikolai Klena, et al. · Nature Communications · 32

Role of cilia in structural birth defects: Insights from ciliopathy mutant mouse models

2014 · Rama Rao Damerla, George C. Gabriel, et al. · Birth Defects Research Part C Embryo Today Reviews · 30

Kinesin-1 activity recorded in living cells with a precipitating dye

2021 · Simona Angerani, Eric Lindberg, et al. · Nature Communications · 29

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Biliary-Atresia-Associated Mannosidase-1-Alpha-2 Gene Regulates Biliary and Ciliary Morphogenesis and Laterality

2020 · Juhoon So, Mylarappa Ningappa, et al. · Frontiers in Physiology · 27

Protofilament-specific nanopatterns of tubulin post-translational modifications regulate the mechanics of ciliary beating

2024 · Gonzalo Alvarez Viar, Nikolai Klena, et al. · Current Biology · 25

Works count: 58

Citation count: 2,786

H-index: 25

I10-index: 28