Author

Ayumu Niida

Observed names: A. Niida, Niida, A., Niida, Ayumu, 歩新居田

Observed institutions: Kyoto University, Ono Pharmaceutical (Japan), Kyoto University Hospital, Meiji Seika Pharma Co., Ltd. (Japan), Takeda (Japan), Tokushima University

ORCID: 0000-0002-6092-2678

Observed ORCID: 0000-0002-6092-2678

OpenAlex ID: A5066356014

Metastin and its variant forms suppress migration of pancreatic cancer cells

2004 · Toshihiko Masui, Ryuichiro Doi, et al. · Biochemical and Biophysical Research Communications · 138

K-Ras(G12D)-selective inhibitory peptides generated by random peptide T7 phage display technology

2017 · Kotaro Sakamoto, Yusuke Kamada, et al. · Biochemical and Biophysical Research Communications · 120

Unequivocal Synthesis of (Z)-Alkene and (E)-Fluoroalkene Dipeptide Isosteres To Probe Structural Requirements of the Peptide Transporter PEPT1

2006 · Ayumu Niida, Kenji Tomita, et al. · Organic Letters · 119

Crystal Structure of a Human K-Ras G12D Mutant in Complex with GDP and the Cyclic Inhibitory Peptide KRpep-2d

2017 · Satoshi Sogabe, Yusuke Kamada, et al. · ACS Medicinal Chemistry Letters · 83

Design and synthesis of downsized metastin (45–54) analogs with maintenance of high GPR54 agonistic activity

2005 · Ayumu Niida, Zixuan Wang, et al. · Bioorganic & Medicinal Chemistry Letters · 74

Transport Characteristics of a Novel Peptide Transporter 1 Substrate, Antihypotensive Drug Midodrine, and Its Amino Acid Derivatives

2006 · Masahiro Tsuda, Tomohiro Terada, et al. · Journal of Pharmacology and Experimental Therapeutics · 62

Structure–activity relationship study on small peptidic GPR54 agonists

2006 · Kenji Tomita, Ayumu Niida, et al. · Bioorganic & Medicinal Chemistry · 53

Diastereoselective Synthesis of New ψ[(E)-CHCMe]- and ψ[(Z)-CHCMe]-type Alkene Dipeptide Isosteres by Organocopper Reagents and Application to Conformationally Restricted Cyclic RGD Peptidomimetics

2002 · Shinya Oishi, Takae Kamano, et al. · The Journal of Organic Chemistry · 53

Application of tri- and tetrasubstituted alkene dipeptide mimetics to conformational studies of cyclic RGD peptides

2005 · Shinya Oishi, Kazuhide Miyamoto, et al. · Tetrahedron · 41

Investigation of the structural requirements of K-Ras(G12D) selective inhibitory peptide KRpep-2d using alanine scans and cysteine bridging

2017 · Ayumu Niida, Shigekazu Sasaki, et al. · Bioorganic & Medicinal Chemistry Letters · 40

Stereoselective Synthesis of 3,6-Disubstituted-3,6-dihydropyridin-2-ones as Potential Diketopiperazine Mimetics Using Organocopper-Mediated anti-SN2‘ Reactions and Their Use in the Preparation of Low-Molecule CXCR4 Antagonists

2006 · Ayumu Niida, Hiroaki Tanigaki, et al. · The Journal of Organic Chemistry · 34

Fmoc‐based solid‐phase synthesis of GPR54‐agonistic pentapeptide derivatives containing alkene‐ and fluoroalkene‐dipeptide isosteres

2007 · Kenji Tomita, Tetsuo Narumi, et al. · Biopolymers · 33

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Synthesis of (Z)-Alkene and (E)-Fluoroalkene-Containing Diketopiperazine Mimetics Utilizing Organocopper-Mediated Reduction−Alkylation and Diastereoselectivity Examination Using DFT Calculations

2006 · Ayumu Niida, Makiko Mizumoto, et al. · The Journal of Organic Chemistry · 33

Efficient Synthesis of Trifluoromethyl and Related Trisubstituted Alkene Dipeptide Isosteres by Palladium-Catalyzed Carbonylation of Amino Acid Derived Allylic Carbonates

2008 · Eriko Inokuchi, Tetsuo Narumi, et al. · The Journal of Organic Chemistry · 32

A novel one-pot reaction involving organocopper-mediated reduction/transmetalation/asymmetric alkylation, leading to the diastereoselective synthesis of functionalized (Z)-fluoroalkene dipeptide isosteres

2006 · Tetsuo Narumi, Ayumu Niida, et al. · Chemical Communications · 31

Stereoselective Synthesis of (Z)-Alkene-Containing Proline Dipeptide Mimetics

2006 · Yoshikazu Sasaki, Ayumu Niida, et al. · The Journal of Organic Chemistry · 28

Diastereoselective Synthesis of ψ[(E)-CMeCH]- and ψ[(E)-CMeCMe]- Type Dipeptide Isosteres Based on Organocopper-Mediated anti-SN2‘ Reaction

2002 · Shinya Oishi, Ayumu Niida, et al. · Organic Letters · 15

Facile access to (Z)-alkene-containing diketopiperazine mimetics utilizing organocopper-mediated anti-SN2′ reactions

2005 · Ayumu Niida, Shinya Oishi, et al. · Tetrahedron Letters · 14

Regio- and stereoselective ring-opening of chiral 1,3-oxazolidin-2-one derivatives by organocopper reagents provides novel access to di-, tri- and tetra-substituted alkene dipeptide isosteresElectronic supplementary information (ESI) available: synthetic procedures and characterization for 4a,b, 5a,b, 7b, 8a,b, 9a,b, 10b, 11a,b, 12b,c, 13b, 14a,b, 15, 16a,b, 17a,b, 18, 19b, 20b. See http://www.rsc.org/suppdata/p1/b2/b203482d/

2002 · Shinya Oishi, Ayumu Niida, et al. · Journal of the Chemical Society Perkin Transactions 1 · 13

Diastereoselective Synthesis of ψ[(E)-CHCMe]- and ψ[(Z)-CHCMe]-Type Dipeptide Isosteres by Organocopper-Mediated anti-SN2‘ Reaction

2002 · Shinya Oishi, Takae Kamano, et al. · Organic Letters · 13

Antiobesity Effect of a Short-Length Peptide YY Analogue after Continuous Administration in Mice

2017 · Naoki Nishizawa, Ayumu Niida, et al. · ACS Medicinal Chemistry Letters · 12

Highly potent antiobesity effect of a short-length peptide YY analog in mice

2017 · Naoki Nishizawa, Ayumu Niida, et al. · Bioorganic & Medicinal Chemistry · 11

Potent antiobesity effect of a short-length peptide YY-analogue continuously administered in mice

2017 · Naoki Nishizawa, Ayumu Niida, et al. · Bioorganic & Medicinal Chemistry Letters · 11

A Short-Length Peptide YY Analogue with Anorectic Effect in Mice

2017 · Naoki Nishizawa, Ayumu Niida, et al. · ACS Omega · 9

Antiobesity and emetic effects of a short-length peptide YY analog and its PEGylated and alkylated derivatives

2017 · Ayumu Niida, Yoko Kanematsu-Yamaki, et al. · Bioorganic & Medicinal Chemistry · 8

Works count: 51

Citation count: 1,082

H-index: 16

I10-index: 23