Get started
Author

Georg Damm

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME
2013 · Patricio Godoy, Nicola J. Hewitt, et al. · Archives of Toxicology · 1,277
PDF
Multilineage communication regulates human liver bud development from pluripotency
2017 · J. Gray Camp, Keisuke Sekine, et al. · Nature · 617
Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis
2020 · Susanne Gaul, Aleksandra Leszczynska, et al. · Journal of Hepatology · 552
Cell sources for in vitro human liver cell culture models
2016 · Katrin Zeilinger, Nora Freyer, et al. · Experimental Biology and Medicine · 227
Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells
2015 · Patricio Godoy, Wolfgang Schmidt-Heck, et al. · Journal of Hepatology · 174
PDF
Toxicogenomics directory of chemically exposed human hepatocytes
2014 · Marianna Grinberg, Regina M. Stöber, et al. · Archives of Toxicology · 144
Manufactured nanomaterials: categorization and approaches to hazard assessment
2014 · Thomas Gebel, Heidi Foth, et al. · Archives of Toxicology · 138
Hepatic 3D cultures but not 2D cultures preserve specific transporter activity for acetaminophen-induced hepatotoxicity
2013 · L. Schyschka, J. J. Martínez Sánchez, et al. · Archives of Toxicology · 127
Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations
2019 · Wiebke Albrecht, Franziska Kappenberg, et al. · Archives of Toxicology · 111
PDF
Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue
2016 · Patricio Godoy, Agata Widera, et al. · Archives of Toxicology · 103
PDF
Featured Article: Isolation, characterization, and cultivation of human hepatocytes and non-parenchymal liver cells
2014 · Elisa Pfeiffer, Victoria Kegel, et al. · Experimental Biology and Medicine · 103
Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control
2018 · Mario Brosch, Kathrin Kattler, et al. · Nature Communications · 98
PDF
Protocol for Isolation of Primary Human Hepatocytes and Corresponding Major Populations of Non-parenchymal Liver Cells
2016 · Victoria Kegel, Daniela Deharde, et al. · Journal of Visualized Experiments · 93
PDF
Direct Transcriptional Regulation of Human Hepatic Cytochrome P450 3A4 (CYP3A4) by Peroxisome Proliferator–Activated Receptor Alpha (PPARα)
2013 · Maria Thomas, Oliver Burk, et al. · Molecular Pharmacology · 92
A Systematic Comparison of the Impact of Inflammatory Signaling on Absorption, Distribution, Metabolism, and Excretion Gene Expression and Activity in Primary Human Hepatocytes and HepaRG Cells
2014 · Marcus Klein, Maria Thomas, et al. · Drug Metabolism and Disposition · 91
Involvement of sphingosine 1-phosphate in palmitate-induced insulin resistance of hepatocytes via the S1P2 receptor subtype
2013 · Susann Fayyaz, Janin Henkel, et al. · Diabetologia · 90
PDF
Critical evaluation of human health risks due to hydraulic fracturing in natural gas and petroleum production
2020 · Klaus-Michael Wollin, G. Damm, et al. · Archives of Toxicology · 75
PDF
High exposure to inorganic arsenic by food: the need for risk reduction
2015 · Ursula Gundert-Remy, Georg Damm, et al. · Archives of Toxicology · 74
Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling
2014 · Katarzyna Mleczko-Sanecka, Franziska Roche, et al. · Blood · 74
Diploid hepatocytes drive physiological liver renewal in adult humans
2022 · Paula Heinke, Fabian Rost, et al. · Cell Systems · 73
PDF
Metabolism of remimazolam in primary human hepatocytes during continuous long-term infusion in a 3-D bioreactor system
2019 · Nora Freyer, Fanny Knöspel, et al. · Drug Design Development and Therapy · 71
PDF
Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes
2016 · Benjamin A. Kandel, Maria Thomas, et al. · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · 70
Induction of active demethylation and 5hmC formation by 5-azacytidine is TET2 dependent and suggests new treatment strategies against hepatocellular carcinoma
2015 · Sahar Olsadat Sajadian, Sabrina Ehnert, et al. · Clinical Epigenetics · 66
PDF
Aromatic hydroxylation is a major metabolic pathway of the mycotoxin zearalenone in vitro
2009 · Erika Pfeiffer, Andreas Hildebrand, et al. · Molecular Nutrition & Food Research · 63
Resolving the Combinatorial Complexity of Smad Protein Complex Formation and Its Link to Gene Expression
2017 · Philippe Lucarelli, Marcel Schilling, et al. · Cell Systems · 60
PDF
Works count: 141
Citation count: 5,936
H-index: 36
I10-index: 63
Year
Topic
Type