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Jiřı́ Vrba

Observed names: J Vrba, J. Vrba, Jiri Vrba, Jiřı ́ Vrba A, Jiří Vrba, Vrba, Jiří
ORCID: 0000-0002-4337-4980
Observed ORCID: 0000-0002-4337-4980
OpenAlex ID: A5069066705
Isoquercitrin: Pharmacology, toxicology, and metabolism
2014 · Kateřina Valentová, Jiří Vrba, et al. · Food and Chemical Toxicology · 478
Flavonolignan 2,3-dehydroderivatives: Preparation, antiradical and cytoprotective activity
2015 · Michaela Pyszková, Michal Biler, et al. · Free Radical Biology and Medicine · 81
Quercetin, Quercetin Glycosides and Taxifolin Differ in their Ability to Induce AhR Activation and CYP1A1 Expression in HepG2 Cells
2012 · Jiri Vrba, Vladimir Kren, et al. · Phytotherapy Research · 72
Cytotoxic activity of sanguinarine and dihydrosanguinarine in human promyelocytic leukemia HL-60 cells
2009 · Jiří Vrba, Petr Doležel, et al. · Toxicology in Vitro · 69
Chelerythrine and dihydrochelerythrine induce G1 phase arrest and bimodal cell death in human leukemia HL-60 cells
2008 · Jiří Vrba, Petr Doležel, et al. · Toxicology in Vitro · 69
Oxidative burst of Kupffer cells: target for liver injury treatment.
2002 · Jiří Vrba, Martin Modrianský · Biomedical Papers · 62
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Protopine and allocryptopine increase mRNA levels of cytochromes P450 1A in human hepatocytes and HepG2 cells independently of AhR
2011 · Jiri Vrba, Eva Vrublova, et al. · Toxicology Letters · 57
A Novel Semisynthetic Flavonoid 7-O-Galloyltaxifolin Upregulates Heme Oxygenase-1 in RAW264.7 Cells via MAPK/Nrf2 Pathway
2013 · Jiří Vrba, Radek Gažák, et al. · Journal of Medicinal Chemistry · 51
Sulfation modulates the cell uptake, antiradical activity and biological effects of flavonoids in vitro: An examination of quercetin, isoquercitrin and taxifolin
2015 · Lenka Roubalová, Kateřina Purchartová, et al. · Bioorganic & Medicinal Chemistry · 50
Induction of heme oxygenase-1 by Macleaya cordata extract and its constituent sanguinarine in RAW264.7 cells
2011 · Jiri Vrba, Eva Orolinova, et al. · Fitoterapia · 42
Effect of UVA radiation on the Nrf2 signalling pathway in human skin cells
2020 · Alena Ryšavá, Kateřina Čížková, et al. · Journal of Photochemistry and Photobiology B Biology · 41
Flavonolignan 2,3-dehydrosilydianin activates Nrf2 and upregulates NAD(P)H:quinone oxidoreductase 1 in Hepa1c1c7 cells
2017 · Lenka Roubalová, Albena T. Dinkova-Kostova, et al. · Fitoterapia · 39
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Involvement of cytochrome P450 1A in sanguinarine detoxication
2004 · Jiřı́ Vrba, Pavel Kosina, et al. · Toxicology Letters · 37
Sulfated Metabolites of Flavonolignans and 2,3-Dehydroflavonolignans: Preparation and Properties
2018 · Kateřina Valentová, Kateřina Purchartová, et al. · International Journal of Molecular Sciences · 33
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Biotransformation of flavonols and taxifolin in hepatocyte in vitro systems as determined by liquid chromatography with various stationary phases and electrospray ionization-quadrupole time-of-flight mass spectrometry
2012 · Jan Vacek, Barbora Papoušková, et al. · Journal of Chromatography B · 33
LC–MS metabolic study on quercetin and taxifolin galloyl esters using human hepatocytes as toxicity and biotransformation in vitro cell model
2013 · Jan Vacek, Barbora Papoušková, et al. · Journal of Pharmaceutical and Biomedical Analysis · 31
Palmatine activates AhR and upregulates CYP1A activity in HepG2 cells but not in human hepatocytes
2014 · Jiri Vrba, Marika Havlikova, et al. · Toxicology in Vitro · 30
Conventional protein kinase C isoenzymes undergo dephosphorylation in neutrophil-like HL-60 cells treated by chelerythrine or sanguinarine
2007 · J. Vrba, Z. Dvořák, et al. · Cell Biology and Toxicology · 30
Effect of the flavonoids quercetin and taxifolin on UVA-induced damage to human primary skin keratinocytes and fibroblasts
2021 · Alena Rajnochová Svobodová, Alena Ryšavá, et al. · Photochemical & Photobiological Sciences · 29
ABC Transporters and Their Role in the Neoadjuvant Treatment of Esophageal Cancer
2018 · David Vrana, Viktor Hlavac, et al. · International Journal of Molecular Sciences · 28
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Metabolism of flavonolignans in human hepatocytes
2018 · Jiří Vrba, Barbora Papoušková, et al. · Journal of Pharmaceutical and Biomedical Analysis · 28
Metabolism of palmatine by human hepatocytes and recombinant cytochromes P450
2014 · Jiri Vrba, Barbora Papouskova, et al. · Journal of Pharmaceutical and Biomedical Analysis · 28
Sanguinarine is a potent inhibitor of oxidative burst in DMSO-differentiated HL-60 cells by a non-redox mechanism
2003 · Jiřı́ Vrba, Jan Hrbáč, et al. · Chemico-Biological Interactions · 28
Protective effect of isoquercitrin against acute dextran sulfate sodium-induced rat colitis depends on the severity of tissue damage
2016 · Norbert Cibiček, Lenka Roubalová, et al. · Pharmacological Reports · 27
Novel flavonolignan hybrid antioxidants: From enzymatic preparation to molecular rationalization
2016 · Eva Vavříková, Vladimír Křen, et al. · European Journal of Medicinal Chemistry · 26
Works count: 56
Citation count: 1,719
H-index: 25
I10-index: 37
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