Get started
Author

Sami Haddad

Utility of physiologically based pharmacokinetic models to drug development and rational drug discovery candidate selection
2003 · Frank-Peter Theil, Theodor W Guentert, et al. · Toxicology Letters · 201
A PBPK Modeling-Based Approach to Account for Interactions in the Health Risk Assessment of Chemical Mixtures
2001 · S. Haddad · Toxicological Sciences · 130
Relative lipid content as the sole mechanistic determinant of the adipose tissue:blood partition coefficients of highly lipophilic organic chemicals
2000 · Sami Haddad, Patrick Poulin, et al. · Chemosphere · 127
Physiological Modeling of Age-Specific Changes in the Pharmacokinetics of Organic Chemicals in Children
2003 · Karine Price, Sami Haddad, et al. · Journal of Toxicology and Environmental Health · 122
Characterization of Age-related Changes in Body Weight and Organ Weights From Birth to Adolescence in Humans
2001 · Sami Haddad, Concetta Restieri, et al. · Journal of Toxicology and Environmental Health · 115
In Vitro–In Vivo Extrapolation of Clearance: Modeling Hepatic Metabolic Clearance of Highly Bound Drugs and Comparative Assessment with Existing Calculation Methods
2011 · Patrick Poulin, Jane R. Kenny, et al. · Journal of Pharmaceutical Sciences · 110
Toxicokinetics of titanium dioxide (TiO2) nanoparticles after inhalation in rats
2016 · Igor Pujalté, Denis Dieme, et al. · Toxicology Letters · 109
Physiological Modeling of the Toxicokinetic Interactions in a Quaternary Mixture of Aromatic Hydrocarbons
1999 · Sami Haddad, Robert Tardif, et al. · Toxicology and Applied Pharmacology · 102
A Physiologically Based Pharmacokinetic Model for the Assessment of Infant Exposure to Persistent Organic Pollutants in Epidemiologic Studies
2008 · Marc-André Verner, Pierre Ayotte, et al. · Environmental Health Perspectives · 97
PDF
Development of Physiologically Based Toxicokinetic Models for Improving the Human Indoor Exposure Assessment to Water Contaminants: Trichloroethylene and Trihalomethanes
2006 · Sami Haddad, Ginette-Charest Tardif, et al. · Journal of Toxicology and Environmental Health · 93
Physiologically Based Pharmacokinetic Modeling of Persistent Organic Pollutants for Lifetime Exposure Assessment: A New Tool in Breast Cancer Epidemiologic Studies
2008 · Marc-André Verner, Michel Charbonneau, et al. · Environmental Health Perspectives · 89
PDF
Validation of a Physiological Modeling Framework for Simulating the Toxicokinetics of Chemicals in Mixtures
2000 · Sami Haddad, Ginette Charest-Tardif, et al. · Toxicology and Applied Pharmacology · 80
The Role of Extracellular Binding Proteins in the Cellular Uptake of Drugs: Impact on Quantitative In Vitro -to- In Vivo Extrapolations of Toxicity and Efficacy in Physiologically Based Pharmacokinetic-Pharmacodynamic Research
2015 · Patrick Poulin, Frank J. Burczynski, et al. · Journal of Pharmaceutical Sciences · 78
PDF
Assessment of air and water contamination by disinfection by-products at 41 indoor swimming pools
2016 · Robert Tardif, Cyril Catto, et al. · Environmental Research · 76
Physiologically-Based Pharmacokinetic (PBPK) Models in Toxicity Testing and Risk Assessment
2012 · John C. Lipscomb, Sami Haddad, et al. · Advances in experimental medicine and biology · 71
Physiological modeling and extrapolation of pharmacokinetic interactions from binary to more complex chemical mixtures.
2002 · Kannan Krishnan, Sami Haddad, et al. · Environmental Health Perspectives · 71
An overview of the literature on emerging pollutants: Chlorinated derivatives of Bisphenol A (ClxBPA)
2021 · N. Plattard, A. Dupuis, et al. · Environment International · 70
PDF
Advancing Prediction of Tissue Distribution and Volume of Distribution of Highly Lipophilic Compounds from a Simplified Tissue-Composition-Based Model as a Mechanistic Animal Alternative Method
2012 · Patrick Poulin, Sami Haddad · Journal of Pharmaceutical Sciences · 70
Toxicokinetic Modeling of Persistent Organic Pollutant Levels in Blood from Birth to 45 Months of Age in Longitudinal Birth Cohort Studies
2012 · Marc-André Verner, Dean Sonneborn, et al. · Environmental Health Perspectives · 66
Comparative Assessment of In Vitro–In Vivo Extrapolation Methods used for Predicting Hepatic Metabolic Clearance of Drugs
2012 · Patrick Poulin, Cornelis E.C.A. Hop, et al. · Journal of Pharmaceutical Sciences · 66
Alteration of infant attention and activity by polychlorinated biphenyls: Unravelling critical windows of susceptibility using physiologically based pharmacokinetic modeling
2010 · M.-A. Verner, P. Plusquellec, et al. · NeuroToxicology · 60
Toward a new paradigm for the efficient in vitro–in vivo extrapolation of metabolic clearance in humans from hepatocyte data
2013 · Patrick Poulin, Sami Haddad · Journal of Pharmaceutical Sciences · 56
Evaluating the neurotoxic effects of lactational exposure to persistent organic pollutants (POPs) in Spanish children
2012 · Mireia Gascon, Marc-André Verner, et al. · NeuroToxicology · 56
Improving the risk assessment of lipophilic persistent environmental chemicals in breast milk
2014 · Geniece M. Lehmann, Marc-André Verner, et al. · Critical Reviews in Toxicology · 52
A methodology for solving physiologically based pharmacokinetic models without the use of simulation softwares
1996 · Sami Haddad, Michael Pelekis, et al. · Toxicology Letters · 52
Works count: 125
Citation count: 3,379
H-index: 33
I10-index: 68
Year
Topic
Type