Author

Ralf Brundiers

Observed names: Brundiers, R., Brundiers, Ralf, R. Brundiers

Observed institutions: MorphoSys (Germany), Max Planck Society, Max Planck Institute of Molecular Physiology, Max Planck Institute for Biophysical Chemistry

OpenAlex ID: A5072050829

Insights into the phosphoryltransfer mechanism of human thymidylate kinase gained from crystal structures of enzyme complexes along the reaction coordinate

2000 · Nils Ostermann, Ilme Schlichting, et al. · Structure · 110

Structural basis for efficient phosphorylation of 3′-azidothymidine monophosphate by Escherichia coli thymidylate kinase

1998 · Arnon Lavie, Nils Ostermann, et al. · Proceedings of the National Academy of Sciences · 88

Crystal Structure of Yeast Thymidylate Kinase Complexed with the Bisubstrate Inhibitor P1-(5‘-Adenosyl) P5-(5‘-Thymidyl) Pentaphosphate (TP5A) at 2.0 Å Resolution: Implications for Catalysis and AZT Activation,

1998 · Arnon Lavie, Manfred Konrad, et al. · Biochemistry · 69

Modifying Human Thymidylate Kinase to Potentiate Azidothymidine Activation

1999 · Ralf Brundiers, Arnon Lavie, et al. · Journal of Biological Chemistry · 62

Potentiating AZT activation: structures of wild-type and mutant human thymidylate kinase suggest reasons for the mutants’ improved kinetics with the HIV prodrug metabolite AZTMP 1 1Edited by J. Karn

2000 · Nils Ostermann, Arnon Lavie, et al. · Journal of Molecular Biology · 52

Kirrel2, a novel immunoglobulin superfamily gene expressed primarily in β cells of the pancreatic islets☆

2003 · Chao Sun, Daniel Kilburn, et al. · Genomics · 37

Recombinant Antibody Expression and Purification

2009 · Achim Knappik, Ralf Brundiers · Springer protocols handbooks/Springer protocols · 16

A novel reverse transduction adenoviral array for the functional analysis of shRNA libraries

2008 · Angelika Oehmig, Andrea Klotzbücher, et al. · BMC Genomics · 10

Expressing engineered thymidylate kinase variants in human cells to improve AZT phosphorylation and human immunodeficiency virus inhibition

2005 · Birgitta M. Wöhrl, Laurence Loubière, et al. · Journal of General Virology · 9

Human thymidylate kinase complexed with the bisubstrate inhibitor AZTP5A

2000 · N. Ostermann, A. Lavie, et al. · Worldwide Protein Data Bank

Mutant human thymidylate kinase (F105Y) complexed with AZTMP and ADP

2000 · N. Ostermann, A. Lavie, et al. · Worldwide Protein Data Bank

Wild type human thymidylate kinase complexed with AZTMP and ADP

2000 · N. Ostermann, A. Lavie, et al. · Worldwide Protein Data Bank

Human thymidylate kinase complexed with ADP, TDP and a magnesium-ion

2000 · N. Ostermann, I. Schlichting, et al. · Worldwide Protein Data Bank

Human thymidylate kinase complexed with thymidine monophosphate, adenosine diphosphate,a magnesium-ion and ALf3

2000 · N. Ostermann, I. Schlichting, et al. · Worldwide Protein Data Bank

Journal of Biological Chemistry

1999 · Brundiers, R., Lavie, A., et al. · MPG.PuRe (Max Planck Society)

Crystal Structure of Yeast Thymidylate Kinase Complexed With the Bisubstrate Inhibitor Tp5a at 2.0 a Resolution: Implications for Catalysis and Azt Activation

1998 · A. Lavie, I. Schlichting, et al. · Worldwide Protein Data Bank

Works count: 29

Citation count: 454

H-index: 9

I10-index: 8