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Vinicius Canale

Observed name: Canale, Vinicius
ORCID: 0000-0002-2030-0268
Observed ORCID: 0000-0002-2030-0268
OpenAlex ID: A5072360573
PTPN2 Regulates Interactions Between Macrophages and Intestinal Epithelial Cells to Promote Intestinal Barrier Function
2020 · Marianne R. Spalinger, Anica Sayoc-Becerra, et al. · Gastroenterology · 146
The JAK Inhibitor Tofacitinib Rescues Intestinal Barrier Defects Caused by Disrupted Epithelial-macrophage Interactions
2020 · Marianne R Spalinger, Anica Sayoc-Becerra, et al. · Journal of Crohn s and Colitis · 79
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T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling
2021 · Ronald R. Marchelletta, Moorthy Krishnan, et al. · Journal of Clinical Investigation · 46
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Autoimmune susceptibility gene PTPN2 is required for clearance of adherent-invasive Escherichia coli by integrating bacterial uptake and lysosomal defence
2021 · Marianne Rebecca Spalinger, Ali Shawki, et al. · Gut · 24
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The autoimmune susceptibility gene, PTPN2 , restricts expansion of a novel mouse adherent-invasive E. coli
2020 · Ali Shawki, Rocio Ramirez, et al. · Gut Microbes · 22
PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice
2023 · Vinicius Canale, Marianne R. Spalinger, et al. · Cellular and Molecular Gastroenterology and Hepatology · 11
Respiratory exposure to agricultural dust extract promotes increased intestinal Tnfα expression, gut barrier dysfunction, and endotoxemia in mice
2023 · Meli’sa S. Crawford, Arzu Ulu, et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 7
PTPN2 Regulates Iron Handling Protein Expression in Inflammatory Bowel Disease Patients and Prevents Iron Deficiency in Mice
2025 · Hillmin Lei, Ali Shawki, et al. · International Journal of Molecular Sciences · 5
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PTPN2 regulates bacterial clearance in a mouse model of enteropathogenic and enterohemorrhagic E. coli infection
2023 · Marianne R. Spalinger, Vinicius Canale, et al. · JCI Insight · 5
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The PTPN2 rs1893217 IBD risk allele increases susceptibility to AIEC invasion by a JAK-STAT-CEACAM6 axis
2025 · Pritha Chatterjee, Vinicius Canale, et al. · Gut Microbes · 4
Intestinal epithelial PTPN2 limits pathobiont colonization by immune-directed antimicrobial responses
2025 · Pritha Chatterjee, Marianne R. Spalinger, et al. · Gut Microbes · 3
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Respiratory Exposure to Agriculture Dust Extract Alters Gut Commensal Species and Key Metabolites in Mice
2025 · Meli'sa S. Crawford, Arzu Ulu, et al. · Journal of Applied Toxicology · 3
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The JAK inhibitor, Tofacitinib, Corrects the Overexpression of CEACAM6 and Limits Susceptibility to AIEC Caused by Reduced Activity of the IBD Associated Gene, PTPN2
2024 · Pritha Chatterjee, Vinicius Canale, et al. · medRxiv · 1
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Constitutive Loss of Ptpn2 in Mice Causes Features of Anemia Including Iron Deficiency
2023 · Hillmin Lei, Ali Shawki, et al. · Physiology · 1
217: Ptpn2 Loss-of-function Reduces Vitamin B12 Levels in Genotyped Crohn's Disease Patients and Intestinal Brush Border Expression of the B12 Transporter, Cubilin, in Mice
2022 · Salomon M. Manz, Vinicius Canale, et al. · Gastroenterology · 1
Myeloid-Intrinsic Protein Tyrosine Phosphatase Non-Receptor Type 2 (PTPN2) Programs Hematopoietic Stem Cells Towards Pro-Inflammatory Macrophages 2309892
2026 · Meera Nair, Samuel Asiedu, et al. · The Journal of Immunology
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Identifying Donor Immune Cells in the Intestinal Mucosa of Chimeric Recipient Mice by Immunofluorescence
2026 · Vinicius Canale, Samuel Asiedu, et al. · Current Protocols
421: the Ibd-candidate Gene, Ptpn2, Is a Critical Regulator of Intestinal Goblet Cell Number, Function, and Differentiation in Mice
2025 · Vinicius Canale, Marianne Spalinger, et al. · Gastroenterology
456: Ptpn2 Phosphatase Loss-of-function Disrupts Iron Homeostasis in Crohn’s Patients and Causes Defective Iron Absorption and Features of Anemia in Mice
2025 · Hillmin Lei, Ali Shawki, et al. · Gastroenterology
Sa1777: THE IBD RISK GENE, PTPN2, REGULATES TH17 RESPONSES MEDIATED BY COMMENSAL SEGMENTED FILAMENTOUS BACTERIA, PROTECTING AGAINST PATHOBIONT COLONIZATION
2025 · Nancy Saad, Pritha Chatterjee, et al. · Gastroenterology
Regulates Iron Handling Protein Expression in Inflammatory Bowel Disease Patients and Prevents Iron Deficiency in Mice
2025 · Lei, Hillmin, Shawki, Ali, et al. · Zurich Open Repository and Archive (University of Zurich)
Loss of Intestinal Epithelial Ptpn2 Selectively Impairs Goblet Cell Differentiation During Type I Immunity Response
2025 · Vinicius Canale, Declan McCole · Gastroenterology
Loss of Intestinal Epithelial Ptpn2 Selectively Impairs Goblet Cell Differentiation During Type I Immunity Response
2025 · Vinicius Canale, Declan McCole · Inflammatory Bowel Diseases
The IBD Risk gene, PTPN2, Is Required for Commensal-associated Th17 Responses to Protect Against Pathobiont Colonization
2024 · Nancy Saad, Pritha Chatterjee, et al. · Physiology
The IBD-candidate gene, PTPN2, Regulates Goblet Cell Number and Expression of Intestinal Epithelial Cell Markers in a Regional-specific Manner in Mice
2023 · Vinicius Canale, Declan McCole · Physiology
Works count: 40
Citation count: 358
H-index: 7
I10-index: 6
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