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Robert E. Babine
Observed names:
R. BABINE,
R. Babine,
R. E. BABINE,
R.E. Babine,
Robert Babine,
Robert E Babine
show all 6
Institution:
Orphagen Pharmaceuticals (United States)
Observed institutions:
University of Wisconsin–Madison,
Eli Lilly (United States),
Pfizer (United States),
Pfizer (United Kingdom),
Princeton University,
Brown University,
Orphagen Pharmaceuticals (United States),
Rebexsess (United States)
show all 8
OpenAlex ID:
A5073199142
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997
·
Robert E. Babine
, Steven L. Bender
·
Chemical Reviews
·
889
Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies
1998
·
Peter S. Dragovich
, Stephen E. Webber
, et al.
·
Journal of Medicinal Chemistry
·
112
Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity Studies
1998
·
Peter S. Dragovich
, Stephen E. Webber
, et al.
·
Journal of Medicinal Chemistry
·
92
Structural and Mutational Analyses of the Molecular Interactions between the Catalytic Domain of Factor XIa and the Kunitz Protease Inhibitor Domain of Protease Nexin 2
2005
·
Duraiswamy Navaneetham
, Lei Jin
, et al.
·
Journal of Biological Chemistry
·
76
Design, Synthesis, and Biological Evaluation of Peptidomimetic Inhibitors of Factor XIa as Novel Anticoagulants
2006
·
Jian Lin
, Hongfeng Deng
, et al.
·
Journal of Medicinal Chemistry
·
74
Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an α-ketothiazole arginine
2006
·
Hongfeng Deng
, Thomas D. Bannister
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
65
The Three-dimensional Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine
2004
·
Lei Jin
, Scott Pluskey
, et al.
·
Journal of Biological Chemistry
·
64
PDF
SAR Exploration Guided by LE and Fsp 3 : Discovery of a Selective and Orally Efficacious RORγ Inhibitor
2015
·
Kazuyuki Hirata
, Masayuki Kotoku
, et al.
·
ACS Medicinal Chemistry Letters
·
62
Crystal Structures of the FXIa Catalytic Domain in Complex with Ecotin Mutants Reveal Substrate-like Interactions
2004
·
Lei Jin
, Pramod Pandey
, et al.
·
Journal of Biological Chemistry
·
61
PDF
Synthesis and in vitro biological evaluation of aryl boronic acids as potential inhibitors of factor XIa
2006
·
Tsvetelina I. Lazarova
, Lei Jin
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
59
The Effect on DNA Cleavage Potency of Tethering a Simple Cyclic Enediyne to a Netropsin Analog
1994
·
M. F. Semmelhack
, J. J. Gallagher
, et al.
·
The Journal of Organic Chemistry
·
51
Asymmetric epoxidation of divinyl carbinol: A new approach to the synthesis of 2,6-dideoxyhexoses
1986
·
Robert E. Babine
·
Tetrahedron Letters
·
44
Design, synthesis and X-ray crystallographic studies of novel FKBP-12 ligands
1995
·
Robert E. Babine
, T.M. Bleckman
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
41
Ternary complex of human ROR γ ligand‐binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment
2017
·
Masato Noguchi
, Akihiro Nomura
, et al.
·
Genes to Cells
·
31
PDF
Mutation of surface residues to promote crystallization of activated factor XI as a complex with benzamidine: an essential step for the iterative structure-based design of factor XI inhibitors
2005
·
Lei Jin
, Pramod Pandey
, et al.
·
Acta Crystallographica Section D Biological Crystallography
·
30
The use of HIV-1 protease structure in inhibitor design
1992
·
Robert E. Babine
, Nan Zhang
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
30
Revision of assignment of structure to the pyrrolodiazepinone antitumor antibiotic sibiromycin
1982
·
Kathlyn A. Parker
, Robert E. Babine
·
Journal of the American Chemical Society
·
25
Revision of the assignment of relative stereochemistry in sibirosamine: synthesis of methyl n-tosyl α-d-disirosaminopyranoside
1982
·
Kathlyn A. Parker
, Robert E. Babine
·
Tetrahedron Letters
·
19
FKBP immunophilin patents for neurological disorders
2005
·
Robert E Babine
, J Ernest Villafranca
, et al.
·
Expert Opinion on Therapeutic Patents
·
13
Conversion of human-selective PPARα agonists to human/mouse dual agonists: a molecular modeling analysis
2004
·
Minmin Wang
, Leonard L. Winneroski
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
11
Design, synthesis and X-ray crystallographic studies of [7.3.1] and [8.3.1] macrocyclic FKBP-12 ligands
1996
·
Robert E. Babine
, T.M. Bleckman
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
11
Synthesis and biological evaluation of a series of HIV-1 protease inhibitors
1993
·
Michael P. Trova
, Robert E. Babine
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
11
Approaches to the isoquinoline quinone antibiotics. Additions of an amino acid derivative to a quinone monoacetal.
1984
·
Kathlyn A. Parker
, Isaac D. Cohen
, et al.
·
Tetrahedron Letters
·
11
Discovery and SAR of JTE-151: A Novel RORγ Inhibitor for Clinical Development
2024
·
Takaki Maeba
, Kazuyuki Hirata
, et al.
·
Journal of Medicinal Chemistry
·
9
Design, structure activity and x-ray crystallographic studies of pseudosymmetrical nonpeptidyl HIV-1 protease inhibitors
1994
·
Robert E. Babine
, Nan Zhang
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
9
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Works count:
59
Citation count:
1,943
H-index:
18
I10-index:
23
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