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Cyril Le Nouën
Observed names:
Cyril Le Nouen,
Le Nouen, Cyril
Institutions:
National Institutes of Health,
National Institute of Allergy and Infectious Diseases,
Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail
Observed institutions:
National Institutes of Health,
National Institute of Allergy and Infectious Diseases,
Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail
ORCID:
0000-0002-5719-4112
Observed ORCID:
0000-0002-5719-4112
OpenAlex ID:
A5073701561
Very virulent infectious bursal disease virus: reduced pathogenicity in a rare natural segment-B-reassorted isolate
2005
·
Cyril Le Nouën
, Gaëlle Rivallan
, et al.
·
Journal of General Virology
·
173
Respiratory Syncytial Virus Interferon Antagonist NS1 Protein Suppresses and Skews the Human T Lymphocyte Response
2011
·
Shirin Munir
, Philippa Hillyer
, et al.
·
PLoS Pathogens
·
128
PDF
Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization
2014
·
Cyril Le Nouën
, Linda G. Brock
, et al.
·
Proceedings of the National Academy of Sciences
·
124
Nonstructural Proteins 1 and 2 of Respiratory Syncytial Virus Suppress Maturation of Human Dendritic Cells
2008
·
Shirin Munir
, Cyril Le Nouen
, et al.
·
Journal of Virology
·
122
Both Genome Segments Contribute to the Pathogenicity of Very Virulent Infectious Bursal Disease Virus
2012
·
Olivier Escaffre
, Cyril Le Nouën
, et al.
·
Journal of Virology
·
117
Actin-Related Protein 2 (ARP2) and Virus-Induced Filopodia Facilitate Human Respiratory Syncytial Virus Spread
2016
·
Masfique Mehedi
, Thomas McCarty
, et al.
·
PLoS Pathogens
·
81
PDF
Different Domains of the RNA Polymerase of Infectious Bursal Disease Virus Contribute to Virulence
2012
·
Cyril Le Nouën
, Didier Toquin
, et al.
·
PLoS ONE
·
80
PDF
Infection and maturation of monocyte-derived human dendritic cells by human respiratory syncytial virus, human metapneumovirus, and human parainfluenza virus type 3
2009
·
Cyril Le Nouën
, Shirin Munir
, et al.
·
Virology
·
65
PDF
A single intranasal dose of a live-attenuated parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in hamsters
2021
·
Xueqiao Liu
, Cindy Luongo
, et al.
·
Proceedings of the National Academy of Sciences
·
62
Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in monkeys
2022
·
Cyril Le Nouën
, Christine E. Nelson
, et al.
·
Cell
·
58
PDF
Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure
2017
·
Cyril Le Nouën
, Thomas McCarty
, et al.
·
Proceedings of the National Academy of Sciences
·
49
PDF
Low CCR7-Mediated Migration of Human Monocyte Derived Dendritic Cells in Response to Human Respiratory Syncytial Virus and Human Metapneumovirus
2011
·
Cyril Le Nouën
, Philippa Hillyer
, et al.
·
PLoS Pathogens
·
43
PDF
Effects of Human Respiratory Syncytial Virus, Metapneumovirus, Parainfluenza Virus 3 and Influenza Virus on CD4+ T Cell Activation by Dendritic Cells
2010
·
Cyril Le Nouën
, Philippa Hillyer
, et al.
·
PLoS ONE
·
39
PDF
Attenuation of Human Respiratory Viruses by Synonymous Genome Recoding
2019
·
Cyril Le Nouën
, Peter L. Collins
, et al.
·
Frontiers in Immunology
·
35
PDF
Human Metapneumovirus SH and G Glycoproteins Inhibit Macropinocytosis-Mediated Entry into Human Dendritic Cells and Reduce CD4 + T Cell Activation
2014
·
Cyril Le Nouën
, Philippa Hillyer
, et al.
·
Journal of Virology
·
29
PDF
Respiratory syncytial virus infection induces a subset of types I and III interferons in human dendritic cells
2017
·
Philippa Hillyer
, Viraj P. Mane
, et al.
·
Virology
·
28
PDF
A Parainfluenza Virus Vector Expressing the Respiratory Syncytial Virus (RSV) Prefusion F Protein Is More Effective than RSV for Boosting a Primary Immunization with RSV
2020
·
Bo Liang
, Yumiko Matsuoka
, et al.
·
Journal of Virology
·
21
Intranasal respiratory syncytial virus vaccine attenuated by codon-pair deoptimization of seven open reading frames is genetically stable and elicits mucosal and systemic immunity and protection against challenge virus replication in hamsters
2024
·
Megan Levy
, Jessica W. Chen
, et al.
·
PLoS Pathogens
·
13
Optimization of the Codon Pair Usage of Human Respiratory Syncytial Virus Paradoxically Resulted in Reduced Viral Replication In Vivo and Reduced Immunogenicity
2019
·
Cyril Le Nouën
, Cindy L. Luongo
, et al.
·
Journal of Virology
·
13
Intranasal immunization with avian paramyxovirus type 3 expressing SARS-CoV-2 spike protein protects hamsters against SARS-CoV-2
2022
·
Hong-Su Park
, Yumiko Matsuoka
, et al.
·
npj Vaccines
·
12
PDF
Live-attenuated pediatric parainfluenza vaccine expressing 6P-stabilized SARS-CoV-2 spike protein is protective against SARS-CoV-2 variants in hamsters
2023
·
Xueqiao Liu
, Hong-Su Park
, et al.
·
PLoS Pathogens
·
10
PDF
Rescue of codon-pair deoptimized respiratory syncytial virus by the emergence of genomes with very large internal deletions that complemented replication
2021
·
Cyril Le Nouën
, Thomas McCarty
, et al.
·
Proceedings of the National Academy of Sciences
·
10
PDF
Mucosal prime-boost immunization with live murine pneumonia virus-vectored SARS-CoV-2 vaccine is protective in macaques
2024
·
Jaclyn A. Kaiser
, Christine E. Nelson
, et al.
·
Nature Communications
·
9
PDF
Reversion mutations in phosphoprotein P of a codon-pair-deoptimized human respiratory syncytial virus confer increased transcription, immunogenicity, and genetic stability without loss of attenuation
2021
·
Jessica W. Chen
, Lijuan Yang
, et al.
·
PLoS Pathogens
·
9
PDF
Lack of Activation Marker Induction and Chemokine Receptor Switch in Human Neonatal Myeloid Dendritic Cells in Response to Human Respiratory Syncytial Virus
2019
·
Cyril Le Nouën
, Philippa Hillyer
, et al.
·
Journal of Virology
·
8
PDF
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Works count:
38
Citation count:
1,356
H-index:
17
I10-index:
22
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