Author

Marella D. Canny

Observed names: Canny, Marella, Canny, Marella D., M. Canny, M.D. Canny, Marella Canny, Marella D Canny, Marella D. Canny

Institution: Texas Tech University

Observed institutions: Texas Tech University, University of Iowa, Mount Sinai Hospital, University of Minnesota, University of Toronto, University of Colorado Boulder, Lunenfeld-Tanenbaum Research Institute, Cancer Prevention and Research Institute of Texas, National Institute of General Medical Sciences

ORCID: 0000-0002-9884-5575

Observed ORCID: 0000-0002-9884-5575

OpenAlex ID: A5073714088

A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice

2013 · Cristina Escribano-Díaz, Alexandre Orthwein, et al. · Molecular Cell · 901

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53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark

2013 · Amélie Fradet-Turcotte, Marella D. Canny, et al. · Nature · 683

Mitosis Inhibits DNA Double-Strand Break Repair to Guard Against Telomere Fusions

2014 · Alexandre Orthwein, Amélie Fradet-Turcotte, et al. · Science · 319

Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR–Cas9 genome-editing efficiency

2017 · Marella D Canny, Nathalie Moatti, et al. · Nature Biotechnology · 271

A therapeutic aptamer inhibits angiogenesis by specifically targeting the heparin binding domain of VEGF 165

2005 · Joon-Hwa Lee, Marella D. Canny, et al. · Proceedings of the National Academy of Sciences · 242

Potent and Selective Inhibitors of the Inositol-requiring Enzyme 1 Endoribonuclease

2011 · Kori Volkmann, Julie L. Lucas, et al. · Journal of Biological Chemistry · 214

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Fast Cleavage Kinetics of a Natural Hammerhead Ribozyme

2004 · Marella D. Canny, Fiona M. Jucker, et al. · Journal of the American Chemical Society · 204

The MMS22L-TONSL Complex Mediates Recovery from Replication Stress and Homologous Recombination

2010 · Lara O'Donnell, Stephanie Panier, et al. · Molecular Cell · 149

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Structure and mechanism of action of the hydroxy–aryl–aldehyde class of IRE1 endoribonuclease inhibitors

2014 · Mario Sanches, Nicole M. Duffy, et al. · Nature Communications · 134

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Nucleosome Acidic Patch Promotes RNF168- and RING1B/BMI1-Dependent H2AX and H2A Ubiquitination and DNA Damage Signaling

2014 · Justin W. Leung, Poonam Agarwal, et al. · PLoS Genetics · 91

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Solution structure of tRNAVal from refinement of homology model against residual dipolar coupling and SAXS data

2008 · Alexander Grishaev, Jinfa Ying, et al. · Journal of Biomolecular NMR · 73

Metal ion specificities for folding and cleavage activity in the Schistosoma hammerhead ribozyme

2008 · Jennifer L. Boots, Marella D. Canny, et al. · RNA · 70

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The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage

2017 · Julianne Kitevski-LeBlanc, Amélie Fradet-Turcotte, et al. · eLife · 56

Efficient Ligation of the Schistosoma Hammerhead Ribozyme

2007 · Marella D. Canny, Fiona M. Jucker, et al. · Biochemistry · 53

A Survey of Reported Disease-Related Mutations in the MRE11-RAD50-NBS1 Complex

2020 · Samiur Rahman, Marella D. Canny, et al. · Cells · 35

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A dynamic allosteric pathway underlies Rad50 ABC ATPase function in DNA repair

2018 · Zachary K. Boswell, Samiur Rahman, et al. · Scientific Reports · 25

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Adjacent mutations in the archaeal Rad50 ABC ATPase D-loop disrupt allosteric regulation of ATP hydrolysis through different mechanisms

2019 · Zachary K Boswell, Marella D Canny, et al. · Nucleic Acids Research · 15

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Mutation of Conserved Mre11 Residues Alter Protein Dynamics to Separate Nuclease Functions

2020 · Samiur Rahman, Mahtab Beikzadeh, et al. · Journal of Molecular Biology · 14

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Dynamic conformations of the P. furiosus MR-DNA complex link Mre11 nuclease activity to DNA-stimulated Rad50 ATP hydrolysis

2025 · Marella D. Canny, Mahtab Beikzadeh, et al. · Communications Biology · 7

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LRET-derived HADDOCK structural models describe the conformational heterogeneity required for DNA cleavage by the Mre11-Rad50 DNA damage repair complex

2022 · Marella D. Canny, Michael P. Latham · eLife · 6

Three segment ligation of a 104 kDa multi-domain protein by SrtA and OaAEP1

2022 · Stephan B. Azatian, Marella D. Canny, et al. · Journal of Biomolecular NMR · 4

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A genetically encoded inhibitor of 53BP1 to stimulate homology-based gene editing

2016 · Marella D. Canny, Leo C.K. Wan, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 3

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DNA Modulates Structural Transitions and Oligomerization Kinetics of the Functional Amyloid CRES

2025 · Ritika Kukreja, Marella D. Canny, et al. · Journal of the American Chemical Society · 1

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Saccharomyces cerevisiae Xrs2 Binds DNA Through Its FHA Domain

2025 · Ajeak Vigneswaran, Marella D. Canny, et al. · Journal of Molecular Biology · 1

Author response: The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage

2017 · Julianne Kitevski-LeBlanc, Amélie Fradet-Turcotte, et al. · 1

Works count: 50

Citation count: 3,572

H-index: 16

I10-index: 18