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Georg Tiefenthaler

A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. Differential reactivity with subsets of immature and mature T lymphocytes.
1989 · T Hünig, H J Wallny, et al. · The Journal of Experimental Medicine · 447
Alternative pathway activation of T cells by binding of CD2 to its cell-surface ligand
1987 · T. Hünig, G. Tiefenthaler, et al. · Nature · 243
Differential thymus dependence of rat CD8 isoform expression
1992 · Nora Torres‐Nagel, Elmar Kraus, et al. · European Journal of Immunology · 124
Brain Shuttle Antibody for Alzheimer’s Disease with Attenuated Peripheral Effector Function due to an Inverted Binding Mode
2018 · Felix Weber, Bernd Bohrmann, et al. · Cell Reports · 105
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Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities
2020 · Steven X. Cho, Ina Rudloff, et al. · Nature Communications · 104
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CART: a conserved antigen receptor transmembrane motif
1994 · Kerry S. Campbell, B.Thomas Bäckström, et al. · Seminars in Immunology · 91
Prospects of bacterial and plant protein-based immunotoxins for treatment of cancer.
2014 · Ulrich H Weidle, Georg Tiefenthaler, et al. · PubMed · 79
The emerging role of new protein scaffold-based agents for treatment of cancer.
2013 · Ulrich H Weidle, Johannes Auer, et al. · PubMed · 72
The Blood-Brain Barrier Challenge for the Treatment of Brain Cancer, Secondary Brain Metastases, and Neurological Diseases.
2015 · Ulrich H Weidle, Jens Niewöhner, et al. · PubMed · 68
A Robust High Throughput Platform to Generate Functional Recombinant Monoclonal Antibodies Using Rabbit B Cells from Peripheral Blood
2014 · Stefan Seeber, Francesca Ros, et al. · PLoS ONE · 62
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Purified lymphocyte function‐associated antigen‐3 and T11 target structure are active in CD2‐mediated T cell stimulation
1987 · Georg Tiefenthaler, Thomas Hünig, et al. · European Journal of Immunology · 57
Identification and characterization of rat T cell subpopulations expressing T cell receptors α/β and γ/δ
1990 · Alexandra Lawetzky, Georg Tiefenthaler, et al. · European Journal of Immunology · 56
Proteases as activators for cytotoxic prodrugs in antitumor therapy.
2014 · Ulrich H Weidle, Georg Tiefenthaler, et al. · PubMed · 48
Targeted delivery of interferon-α to hepatitis B virus-infected cells using T-cell receptor-like antibodies
2012 · Changhua Ji, Konduru S.R. Sastry, et al. · Hepatology · 45
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The intriguing options of multispecific antibody formats for treatment of cancer.
2013 · Ulrich H Weidle, Georg Tiefenthaler, et al. · PubMed · 40
T11TS, the cell surface molecule binding to the “erythrocyte receptor” of T lymphocytes: cellular distribution, purification to homogeneity and biochemical properties
1986 · Thomas Hünig, Rita Mitnacht, et al. · European Journal of Immunology · 39
Serologic cross-reactivity of T11 target structure and lymphocyte function-associated antigen 3. Evidence for structural homology of the sheep and human ligands of CD2.
1987 · G Tiefenthaler, M L Dustin, et al. · The Journal of Immunology · 23
Potential of Protein-based Anti-metastatic Therapy with Serpins and Inter α-Trypsin Inhibitors
2018 · ULRICH H. WEIDLE, FABIAN BIRZELE, et al. · Cancer Genomics & Proteomics · 22
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T cell receptor α‐chain tail is required for protein kinase C‐mediated down‐regulation, but not for signaling
1997 · B. Thomas Bäckström, Bent Rubin, et al. · European Journal of Immunology · 21
Restricted expression of CD2 among subsets of sheep thymocytes and T lymphocytes.
1989 · G W Giegerich, W R Hein, et al. · PubMed Central · 20
The role of CD2/LFA-3 interaction in antigen- and mitogen-induced activation of human T cells
1989 · Georg Tiefenthaler, Thomas Hünlg · International Immunology · 19
Protein engineering of a stable and potent anti-inflammatory IL-37-Fc fusion with enhanced therapeutic potential
2021 · Alexander Bujotzek, Georg Tiefenthaler, et al. · Cell chemical biology · 17
The translational potential for target validation and therapy using intracellular antibodies in oncology.
2013 · Ulrich H Weidle, Daniela Maisel, et al. · PubMed · 13
T-cell Subpopulations Expressing Distinct Forms of the TCR in Normal, Athymic, and Neonatally TCR -suppressed Rats
1989 · T. Hunig, G. Tiefenthaler, et al. · Cold Spring Harbor Symposia on Quantitative Biology · 13
Maturation of CD4−8−α/β TCR+T cells induced by CD2-stimulation in vivo and in vitro
1992 · Georg Tiefenthaler, Thomas Hanke, et al. · International Immunology · 11
Works count: 39
Citation count: 1,876
H-index: 20
I10-index: 26
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